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Recombinant Human C6 protein, His/T7-tagged

Cat.No. : C6-10552H
Product Overview : Recombinant Human C6(Gln682~Ala934) fused with His/T7 tag at N-terminal was expressed in E. coli.
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Description : This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.
Source : E. coli
Species : Human
Tag : His/T7
Form : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Molecular Mass : 31.9kDa
Protein length : Gln682~Ala934
AA Sequence : MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- QYFRCLPDG TWRQGDVECQ RTECIKPVVQ EVLTITPFQR LYRIGESIEL TCPKGFVVAG PSRYTCQGNS WTPPISNSLT CEKDTLTKLK GHCQLGQKQS GSECICMSPE EDCSHHSEDL CVFDTDSNDY FTSPACKFLA EKCLNNQQLH FLHIGSCQDG RQLEWGLERT RLSSNSTKKE SCGYDTCYDW EKCSASTSKC VCLLPPQCFK GGNQLYCVKM GSSTSEKTLN ICEVGTIRCA NRKMEILHPG KCLA
Endotoxin : <1.0eu per 1µg (determined by the lal>
Purity : >95%
Applications : SDS-PAGE; WB; ELISA; IP.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : C6 complement component 6 [ Homo sapiens ]
Official Symbol : C6
Synonyms : C6; complement component 6; complement component C6;
Gene ID : 729
mRNA Refseq : NM_000065
Protein Refseq : NP_000056
MIM : 217050
UniProt ID : P13671
Chromosome Location : 5p13
Pathway : Complement Activation, Classical Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem;
Function : protein binding;

Products Types

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C6-0098H Recombinant Human C6 Protein, GST-Tagged +Inquiry
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◆ Native Protein
C6-101H Native Human C6 Protein +Inquiry
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◆ Lysates
C6-1647HCL Recombinant Human C6 cell lysate +Inquiry

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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