Recombinant Human C6 Protein, GST-Tagged

• Cat.No.: C6-0098H
• Product Overview: Human C6 full-length ORF (AAH35723, 23 a.a. - 934 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 125.84 kDa
• AA Sequence: FCDHYAWTQWTSCSKTCNSGTQSRH RQIVVDKYYQENFCEQICSKQETRE CNWQRCPINCLLGDFGPWSDCDPCI EKQSKVRSVLRPSQFGGQPCTEPLV AFQPCIPSKLCKIEEADCKNKFRCD SGRCIARKLECNGENDCGDNSDERD CGRTKAVCTRKYNPIPSVQLMGNGF HFLAGEPRGEVLDNSFTGGICKTVK SSRTSNPYRVPANLENVGFEVQTAE DDLKTDFYKDLTSLGHNENQQGSFS SQGGSSFSVPIFYSSKRSENINHNS AFKQAIQASHKKDSSFIRIHKVMKV LNFTTKAKDLHLSDVFLKALNHLPL EYNSALYSRIFDDFGTHYFTSGSLG GVYDLLYQFSSEELKNSGLTEEEAK HCVRIETKKRVLFAKKTKVEHRCTT NKLSEKHEGSFIQGAEKSISLIRGG RSEYGAALAWEKGSSGLEEKTFSEW LESVKENPAVIDFELAPIVDLVRNI PCAVTKRNNLRKALQEYAAKFDPCQ CAPCPNNGRPTLSGTECLCVCQSGT YGENCEKQSPDYKSNAVDGQWGCWS SWSTCDATYKRSRTRECNNPAPQRG GKRCEGEKRQEEDCTFSIMENNGQP CINDDEEMKEVDLPEIEADSGCPQP VPPENGFIRNEKQLYLVGEDVEISC LTGFETVGYQYFRCLPDGTWRQGDV ECQRTECIKPVVQEVLTITPFQRLY RIGESIELTCPKGFVVAGPSRYTCQ GNSWTPPISNSLTCEKDTLTKLKGH CQLGQKQSGSECICMSPEEDCSHHS EDLCVFDTDSNDYFTSPACKFLAEK CLNNQQLHFLHIGSCQDGRQLEWGL ERTRLSSNSTKKESCGYDTCYDWEK CSASTSKCVCLLPPQCFKGGNQLYC VKMGSSTSEKTLNICEVGTIRCANR KMEILHPGKCLA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: C6 complement component 6 [ Homo sapiens ]
• Official Symbol: C6
• Synonyms: C6; complement component 6; complement component C6
• Gene ID: 729
• mRNA Refseq: NM_000065
• Protein Refseq: NP_000056
• MIM: 217050
• UniProt ID: P13671