Recombinant Human Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase), GST-Tagged
Cat.No. : | MMP3-1383H |
Product Overview : | MMP-3 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain fused to a GST tag containing 228 amino acids (251-478) and having a total molecular mass of 51kDa. MMP-3 is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | MMP3-1383H |
Description : | MMP-3 enzyme is also known as Stromelysin-1or as Transin-1 which hydrolyzes natural collagen at physiological pH and temperature. It dissolves the intervertebral nucleus pulposus and annulus fibrosus of Herniated Lumbar Intervertebral Disk . MMP-3 hydrolyzes components of the extracellular matrix like proteoglycan, laminin, fibronectin, gelatin and collagen types III, IV and IX. It also activates pro-MMP-9 and pro-MMP-8 and superactivates plasmin activated MMP-1. MMP-3 is secreted as a latent proenzyme and is activated by a variety of proteinases, e.g. plasmin, trypsin, chymotrypsin, cathepsin G or human neutrophil elastase. MMP-3 was found to be capable of activating the precursor of IL1-beta. |
Source : | Human |
Host : | Escherichia Coli. |
Form : | MMP-3 is supplied in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol. |
Physical Appearance : | Sterile Filtered clear solution. |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
Gene Name : | MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) [ Homo sapiens ] |
Official Symbol : | MMP3 |
Synonyms : | MMP3; matrix metallopeptidase 3 (stromelysin 1, progelatinase); SL-1; STMY; STR1; CHDS6; MMP-3; STMY1; MGC126102; MGC126103; MGC126104; stromelysin-1; transin-1; proteoglycanase; OTTHUMP00000045949; matrix metalloproteinase-3; matrix metalloproteinase 3 (stromelysin 1, progelatinase); Stromelysin-1; Matrix metalloproteinase-3; Transin-1; EC 3.4.24 |
Gene ID : | 4314 |
mRNA Refseq : | NM_002422 |
Protein Refseq : | NP_002413 |
MIM : | 185250 |
UniProt ID : | P08254 |
Chromosome Location : | 11q22.3 |
Pathway : | Matrix Metalloproteinases; Rheumatoid arthritis; p75(NTR)-mediated signaling |
Function : | calcium ion binding; metalloendopeptidase activity; peptidase activity; protein complex binding; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
MMP3-1420H | Recombinant Human MMP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mmp3-10594M | Recombinant Mouse Mmp3 Protein, His (Fc)-Avi-tagged | +Inquiry |
MMP3-555H | Recombinant Human MMP3 Protein, MYC/DDK-tagged | +Inquiry |
MMP3-2450H | Recombinant Human MMP3 Protein, His-tagged | +Inquiry |
MMP3-2449H | Recombinant Human MMP3 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
MMP3-26C | Collagenase Type 3 Protein | +Inquiry |
◆ Lysates | ||
MMP3-4273HCL | Recombinant Human MMP3 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0589 | MMP-3 Activity Assay Kit | +Inquiry |
Kit-2213 | MMP-3 Activity Fluorometric Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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