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MMP10

  • Official Full Name

    matrix metallopeptidase 10 (stromelysin 2)

  • Overview

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Synonyms

    MMP10; matrix metallopeptidase 10 (stromelysin 2); SL-2; STMY2; stromelysin-2; MMP-10; transin 2; transin-2; stromelysin 2; matrix metalloprotease 10; matrix metalloproteinase-10; matrix metalloproteinase 10 (stromelysin 2);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rabbit
  • Rat
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mouse myeloma cell line NS0
  • Wheat Germ
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MMP10-01H Active Recombinant Human MMP10 Protein Mouse myeloma cell line NS0
Human MMP10-440H Recombinant Human matrix metallopeptidase 10 (stromelysin 2), His-tagged E.coli His
Human MMP10-156H Recombinant Human matrix MMP10 (Stromelysin 2), Catalytic Domain E.coli N/A
Human MMP10-5041H Recombinant Human MMP10, His-tagged E.coli His
Human MMP10-4282HCL Recombinant Human MMP10 293 Cell Lysate HEK293 N/A
Human MMP10-1457H Recombinant Human MMP10 Protein (99-476 aa), His-tagged Yeast His 99-476 aa
Human MMP10-6406HF Recombinant Full Length Human MMP10 Protein, GST-tagged In Vitro Cell Free System GST 476 amino acids
Human MMP10-5415H Recombinant Human MMP10 Protein, GST-tagged Wheat Germ GST
Human MMP10-4573H Recombinant Human MMP10 Protein (Tyr18-Cys476), N-His tagged E.coli N-His Tyr18-Cys476
Human MMP10-4572H Recombinant Human MMP10 Protein (18-476), His tagged E.coli His 18-476
Mouse Mmp10-727M Recombinant Mouse Mmp10 protein, His & T7-tagged E.coli His/T7 Glu154~Ser472 (Accession # O55123)
Rat MMP10-3710R Recombinant Rat MMP10 Protein Mammalian Cell His
Rat Mmp10-728R Recombinant Rat Mmp10 protein, His & T7-tagged E.coli His/T7 Glu154~Thr465 (Accession # P07152)
Rat MMP10-3366R-B Recombinant Rat MMP10 Protein Pre-coupled Magnetic Beads HEK293
Rat MMP10-3366R Recombinant Rat MMP10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rabbit MMP10-1118R Recombinant Rabbit MMP10 Protein, His-tagged E.coli N-His Asn21-Ala283
Chicken MMP10-5355C Recombinant Chicken MMP10 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

MMP10 involved in several pathways and played different roles in them. We selected most pathways MMP10 participated on our site, such as Activation of Matrix Metalloproteinases, Collagen degradation, Degradation of the extracellular matrix, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMP10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activation of Matrix MetalloproteinasesMMP13;TIMP2;MMP17;CTSLL;CTSL2;CMA1;MMP10;MMP8;CTSG
Collagen degradationCOL13A1;ADAM9;MMP19;ADAM10;MMP11;CTSB;MGC174155;MMP12;EMID2
Degradation of the extracellular matrixTLL1;LOC100686744;ADAM9;CTSL2;TIMP2B;COL17A1;MGC174857;BMP1;CTSD
Extracellular matrix organizationEFEMP1;COL8A1A;PPIB;LOC100686744;CMA1;ADAMTS5;MGC174155;DAG1;DMP1
Matrix MetalloproteinasesMMP8;MMP11;MMP26;MMP12;MMP15;MMP28;MMP20;MMP27;MMP25

MMP10 has several biochemical functions, for example, calcium ion binding, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MMP10 itself. We selected most functions MMP10 had, and list some proteins which have the same functions with MMP10. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingNUCB2;CDH1;PCDH2AA15;PRKCSH;PCDH2AB8;GUCA1C;OC90;FSTL1A;CALML3
metalloendopeptidase activityPAPPA;UQCRC2B;ADAMTS3;ECEL1;ADAM5P;GM12824;ADAM8;ADAMDEC1;ADAMTS8
zinc ion bindingUQCRC1;POLR2I;AGBL4;MAN2C1;NHLRC1;ZFP385C;DTX1;MMP3;EP300

MMP10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMP10 here. Most of them are supplied by our site. Hope this information will be useful for your research of MMP10.

Gene Family

MMPs

Research Area

Related articles

Yeo, ASL; Azhar, NA; et al. Lack of Clinical Manifestations in Asymptomatic Dengue Infection Is Attributed to Broad Down-Regulation and Selective Up-Regulation of Host Defence Response Genes. PLOS ONE 9:-(2014).
Bernal-Lopez, MR; Garrido-Sanchez, L; et al. Antioxidized LDL Antibodies Are Associated With Different Metabolic Pathways in Patients With Atherosclerotic Plaque and Type 2 Diabetes. DIABETES CARE 36:1006-1011(2013).
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