|Official Full Name||matrix metallopeptidase 10 (stromelysin 2)|
|Background||Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]|
|Synonyms||MMP10; matrix metallopeptidase 10 (stromelysin 2); SL-2; STMY2; stromelysin-2; MMP-10; transin 2; transin-2; stromelysin 2; matrix metalloprotease 10; matrix metalloproteinase-10; matrix metalloproteinase 10 (stromelysin 2)|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
mmp10 involved in several pathways and played different roles in them. We selected most pathways mmp10 participated on our site, such as Activation of Matrix Metalloproteinases, Collagen degradation, Degradation of the extracellular matrix, which may be useful for your reference. Also, other proteins which involved in the same pathway with mmp10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Activation of Matrix Metalloproteinases||TPSAB1; MMP8; MMP13; TIMP2B; CTSL2; MGC174857; CTRB1; MMP15; MGC174155; MMP17|
|Collagen degradation||ADAM10; CTS7; MGC174857; TLDC2; MMP10; EMID2; CTSL1; CTSLL; COL25A1; MMP15|
|Degradation of the extracellular matrix||ADAM15; CTSK; MGC174155; TLL1; ADAMTS8; COL9A3; TPSAB1; CTSB; TIMP2A; KLK7|
|Extracellular matrix organization||PCOLCE2; DST; COL16A1; LTBP3; MMP13; COL28A1; TPSAB1; FMOD; TLDC2; PCOLCE2B|
|Matrix Metalloproteinases||MMP24; MMP19; MMP8; TIMP4; MMP15; MMP23B; MMP26; MMP25; TIMP2; MMP12|
mmp10 has several biochemical functions, for example, calcium ion binding, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by mmp10 itself. We selected most functions mmp10 had, and list some proteins which have the same functions with mmp10. You can find most of the proteins on our site.
|calcium ion binding||PCDHB12; ICN; CAPN3; SNCB; PCDH15; PCDH2AB1; PRF1; FLG; MMP15; PLA2G10|
|metalloendopeptidase activity||PAPPA; ADAM8A; PAPPAB; ADAM5; MMP2; ADAMTS4; OMA1; ECEL1; HE1B; ADAMTS18|
|zinc ion binding||BAZ1A; ZMAT4; RAG1; NR3C2; SEC23A; LMX1BB; P2RX1; LIMK1A; CBL; RING1|
mmp10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with mmp10 here. Most of them are supplied by our site. Hope this information will be useful for your research of mmp10.