mmp7
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  • Official Full Name
  • matrix metallopeptidase 7 (matrilysin, uterine)
  • Background
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Synonyms
  • MMP7; matrix metallopeptidase 7 (matrilysin, uterine); MMP-7; MPSL1; PUMP-1; matrilysin; matrin; pump-1 protease; uterine matrilysin; uterine metalloproteinase; matrix metalloproteinase-7; matrix metalloproteinase 7 (matrilysin, uterine); MAT
Cat.#:MMP7-5435HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MMP7 Protein, GST-tagged
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Cat.#:MMP7-40HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MMP7
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Cat.#:MMP7-47HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MMP7 protein, His-tagged
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Cat.#:MMP7-810HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human MMP7, Fc tagged
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Cat.#:MMP7-94Tag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant ProMatrix Metalloproteinase-7
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Cat.#:Mmp7-203MTag:
Source (Host):NSO cellsSpecies:Mouse
Product nameRecombinant Mouse Mmp7
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Cat.#:Mmp7-748MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Mmp7 protein, His-tagged
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Cat.#:MMP7-3718RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MMP7 Protein
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Cat.#:Mmp7-749RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Mmp7 protein, His & T7-tagged
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Cat.#:MMP7-1425CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MMP7
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Cat.#:MMP7-28205THTag:
Source (Host):Species:Human
Product nameNative Human MMP7
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Cat.#:MMP7-2883HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human MMP7 cell lysate
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Involved Pathway

MMP7 involved in several pathways and played different roles in them. We selected most pathways MMP7 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMP7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Wnt signaling pathway
FZD8B; NFATC4; WNT9B; NLK1; FZD9B; SKP1; CACYBP; PRKCBA; SENP2; WNT1

Protein Function

MMP7 has several biochemical functions, for example, heparin binding, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MMP7 itself. We selected most functions MMP7 had, and list some proteins which have the same functions with MMP7. You can find most of the proteins on our site.
Function
Related Protein
Function heparin binding
Related Protein PTPRF; FGF9; SLIT3; GPNMB; THBS3; MPO; MSTN; RSPO3; CFH; CCL2
Function metalloendopeptidase activity
Related Protein MMP9; MEP1A.1; AFG3L2; ADAMTS13; ADAM23; MMP14; PITRM1; TLL1; YBEY; IDE
Function zinc ion binding
Related Protein BTY; KMT2A; HDAC4; ZCCHC11; MT1E; ZNRF2A; PGLYRP6; NR2E3; RNF13; NR2C1

Interacting Protein

MMP7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMP7 here. Most of them are supplied by our site. Hope this information will be useful for your research of MMP7.
ELN; FASLG

MMP7 Related Articles

Kim, GE; Lee, JS; et al. Expression of matrix metalloproteinases and their inhibitors in different immunohistochemical-based molecular subtypes of breast cancer. BMC CANCER 14:-(2014).
Mitsui, H; Suarez-Farinas, M; et al. Gene Expression Profiling of the Leading Edge of Cutaneous Squamous Cell Carcinoma: IL-24-Driven MMP-7. JOURNAL OF INVESTIGATIVE DERMATOLOGY 134:1418-1427(2014).

MMP7 Related Gene Family

MMPs