Recombinant Human MMP3 Protein, His-tagged
Cat.No. : | MMP3-2450H |
Product Overview : | Recombinant Human MMP3 Protein (Arg101-Cys477) with a N-His tag was expressed in E. coli. |
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Description : | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 46.4 kDa Accurate Molecular Mass: 50 kDa |
Protein length : | Arg101-Cys477 |
Endotoxin : | <1.0 EU per 1µg (determined by the LAL method). |
Purity : | > 90% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) [ Homo sapiens (human) ] |
Official Symbol : | MMP3 |
Synonyms : | MMP3; matrix metallopeptidase 3 (stromelysin 1, progelatinase); matrix metalloproteinase 3 (stromelysin 1, progelatinase), STMY, STMY1; stromelysin-1; transin-1; proteoglycanase; matrix metalloproteinase-3; matrix metalloproteinase 3 (stromelysin 1, progelatinase); SL-1; STMY; STR1; CHDS6; MMP-3; STMY1; MGC126102; MGC126103; MGC126104; |
Gene ID : | 4314 |
mRNA Refseq : | NM_002422 |
Protein Refseq : | NP_002413 |
MIM : | 185250 |
UniProt ID : | P08254 |
Products Types
◆ Recombinant Protein | ||
Mmp3-10594M | Recombinant Mouse Mmp3 Protein, His (Fc)-Avi-tagged | +Inquiry |
MMP3-2449H | Recombinant Human MMP3 Protein, His-tagged | +Inquiry |
MMP3-240H | Recombinant Human MMP3 Protein, His-tagged(C-ter) | +Inquiry |
Mmp3-7422R | Recombinant Rat Mmp3 protein, His-tagged | +Inquiry |
MMP3-1123H | Recombinant Human MMP3 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
MMP3-26C | Native Clostridium histolyticum Collagenase Type 3 Protein | +Inquiry |
◆ Lysates | ||
MMP3-4273HCL | Recombinant Human MMP3 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2213 | MMP-3 Activity Fluorometric Assay Kit | +Inquiry |
Kit-0589 | MMP-3 Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMMP3 breaks down extracellular matrix components, aiding in tissue remodeling and repair.
MMP3 facilitates cancer metastasis by altering the tumor microenvironment and promoting invasion.
Changes in MMP3 activity can accelerate skin aging and contribute to dermatological conditions.
MMP3 influences cardiovascular health by affecting arterial wall remodeling and stability.
MMP3 contributes to arthritis progression by degrading joint cartilage and connective tissues.
MMP3 modulates inflammation, impacting tissue inflammation and repair processes.
MMP3 plays a role in wound healing by remodeling damaged tissues and aiding in repair.
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