MMP16

  • Official Full Name

    matrix metallopeptidase 16 (membrane-inserted)

  • Overview

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq, Oct 2010]
  • Synonyms

    MMP16; matrix metallopeptidase 16 (membrane-inserted); MMP-X2; C8orf57; MT-MMP2; MT-MMP3; MT3-MMP; matrix metalloproteinase-16; MMP-16; MT3MMP; MTMMP3; MT-MMP 3; Putative transmembrane protein C8orf57; membrane-type matrix metalloproteinase 3; membrane-type-3 matrix metalloproteinase;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MMP16-7089H Recombinant Human MMP16 protein, His & T7-tagged E.coli His/T7 Ala351~Asn557 (Accession # P51512)
Human MMP16-608H Recombinant Human MMP16, Catalytic Domain E.coli N/A
Human MMP16-712H Recombinant Human MMP16 protein, His-tagged E.coli His 33-400 aa
Rat MMP16-3714R Recombinant Rat MMP16 Protein Mammalian Cell His
Rat MMP16-3370R Recombinant Rat MMP16 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MMP16-3370R-B Recombinant Rat MMP16 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL25871HF Recombinant Full Length Human Matrix Metalloproteinase-16(Mmp16) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (120-607)
Rattus norvegicus (Rat) RFL7251RF Recombinant Full Length Rat Matrix Metalloproteinase-16(Mmp16) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (120-607)
Chicken MMP16-6751C Recombinant Chicken MMP16 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

MMP16 involved in several pathways and played different roles in them. We selected most pathways MMP16 participated on our site, such as MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMP16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MicroRNAs in cancerPTEN;Pdgfa&Pdgfb;SLC45A3;TTC6;KIF23;SHC4;MAP2K1;PDGFRA;ZFPM2

MMP16 has several biochemical functions, for example, calcium ion binding, enzyme activator activity, metalloendopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MMP16 itself. We selected most functions MMP16 had, and list some proteins which have the same functions with MMP16. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingEDEM2;RASGRP3;SYT5B;ANXA1A;PCDH7;PEF1;PLA2G4B;MMP17;NOX5
enzyme activator activitySEC14L2;APOA5;SLX4;CASP9;SFTPBB;ASAP2;TRIM23;GM749;ALDH1A2
metalloendopeptidase activityPAPPAA;HE1A;MMP2;ADAM33;MMP9;ECE1;ADAM10A;ECE2;MMP1A
zinc ion bindingPIAS2;ADAMTS9;TRIM69;VDRB;RNF19A;RNF40;S100A13;LMO4B;BTR12

MMP16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMP16 here. Most of them are supplied by our site. Hope this information will be useful for your research of MMP16.

Gorasp2

Gene Family

MMPs

Research Area

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