MMP16

Official Full Name

matrix metallopeptidase 16 (membrane-inserted)
Overview

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq, Oct 2010]
Synonyms

MMP16; matrix metallopeptidase 16 (membrane-inserted); MMP-X2; C8orf57; MT-MMP2; MT-MMP3; MT3-MMP; matrix metalloproteinase-16; MMP-16; MT3MMP; MTMMP3; MT-MMP 3; Putative transmembrane protein C8orf57; membrane-type matrix metalloproteinase 3; membrane-type-3 matrix metalloproteinase;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Homo sapiens (Human)
Human
Rat
Rattus norvegicus (Rat)

Source

E.coli
E.coli expression system
HEK293
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MMP16-7089H	Recombinant Human MMP16 protein, His & T7-tagged	E.coli	His&T7	Ala351~Asn557	Inquiry
Human	MMP16-608H	Recombinant Human MMP16, Catalytic Domain	E.coli	Non		Inquiry
Human	MMP16-712H	Recombinant Human MMP16 protein, His-tagged	E.coli	His	33-400 aa	Inquiry
Rat	MMP16-3714R	Recombinant Rat MMP16 Protein	Mammalian Cell	His		Inquiry
Rat	MMP16-3370R	Recombinant Rat MMP16 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Rat	MMP16-3370R-B	Recombinant Rat MMP16 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Homo sapiens (Human)	RFL25871HF	Recombinant Full Length Human Matrix Metalloproteinase-16(Mmp16) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (120-607)	Inquiry
Rattus norvegicus (Rat)	RFL7251RF	Recombinant Full Length Rat Matrix Metalloproteinase-16(Mmp16) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (120-607)	Inquiry
Chicken	MMP16-6751C	Recombinant Chicken MMP16	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

MMP16 involved in several pathways and played different roles in them. We selected most pathways MMP16 participated on our site, such as MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMP16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
MicroRNAs in cancer	ABCB1;PDCD4;CYP24A1;KIF23;Abcb1b;MDM2;PTEN;NFKB1;PDGFB

MMP16 has several biochemical functions, for example, calcium ion binding, enzyme activator activity, metalloendopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MMP16 itself. We selected most functions MMP16 had, and list some proteins which have the same functions with MMP16. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	MGP;CALML3;ACTN2B;CANX;PCDH1GB9;PADI4;CABS1;S100V2;EFHA2
enzyme activator activity	GLC8;ARL1;CLPSL1;GM1679;MMP16;DBNL;MGST2;CTAGE5;SEC14L2
metalloendopeptidase activity	MIPEP;ECEL1;MMP2;HE1A;MMP17;HE1B;MMP9;C6AST3;ADAM8
zinc ion binding	RNF141;AJUBA;ZMAT4;MSRB3;CA7;TRIM43A;ZCCHC8;TRIM35-21;LHX3

MMP16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMP16 here. Most of them are supplied by our site. Hope this information will be useful for your research of MMP16.

Gorasp2