MMP26

Official Full Name

matrix metallopeptidase 26
Overview

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. [provided by RefSeq, Jul 2008]
Synonyms

MMP26; matrix metallopeptidase 26; matrix metalloproteinase-26; MMP-26; endometase; matrilysin 2; matrilysin-2; matrix metalloproteinase 26;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MMP26-338H	Recombinant Human MMP26 protein(Thr90-Pro261)	E.coli	Non	Thr90-Pro261	Inquiry
Human	MMP26-4274HCL	Recombinant Human MMP26 293 Cell Lysate	HEK293	Non		Inquiry
Human	MMP26-5430H	Recombinant Human MMP26 Protein, GST-tagged	Wheat Germ	GST		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

MMP26 involved in several pathways and played different roles in them. We selected most pathways MMP26 participated on our site, such as Matrix Metalloproteinases, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMP26 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Matrix Metalloproteinases	BSG;MMP26;MMP17;MMP8;MMP12;MMP27;TIMP4;MMP23B;MMP25

MMP26 has several biochemical functions, for example, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MMP26 itself. We selected most functions MMP26 had, and list some proteins which have the same functions with MMP26. You can find most of the proteins on our site.

Function	Related Protein
metalloendopeptidase activity	MMEL1;ADAM5P;ASTL;ADAM9;MME;ADAMTS1;MMP25;ADAMTS3;ADAMDEC1
zinc ion binding	NR1D2B;ZEB1;WBP4;PHF17;ZFP598;MMP16;MORC3;BBOX1;AEBP1

MMP26 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMP26 here. Most of them are supplied by our site. Hope this information will be useful for your research of MMP26.