MMP24

  • Official Full Name

    matrix metallopeptidase 24 (membrane-inserted)

  • Overview

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. [provided by RefSeq, Jul 2008]
  • Synonyms

    MMP24; matrix metallopeptidase 24 (membrane-inserted); MMP25; MMP-24; MT5MMP; MTMMP5; MT-MMP5; MT5-MMP; MT-MMP 5; matrix metalloproteinase-24; membrane-type 5 matrix metalloproteinase; membrane-type matrix metalloproteinase 5; membrane-type-5 matrix metalloproteinase; matrix metalloproteinase 24 (membrane-inserted);

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|Myc
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MMP24-610H Recombinant Human MMP24, Catalytic Domain, His-tagged E.coli His
Human MMP24-3942H Recombinant Human MMP24 Protein (Ile429-Gln642), N-His tagged E.coli N-His Ile429-Gln642
Mouse MMP24-9920M Recombinant Mouse MMP24 Protein Mammalian Cell His
Mouse MMP24-5604M-B Recombinant Mouse MMP24 Protein Pre-coupled Magnetic Beads HEK293
Mouse MMP24-2455M Recombinant Mouse MMP24 Protein (42-575 aa), His-Myc-tagged E.coli His/Myc 42-575 aa
Mouse MMP24-5604M Recombinant Mouse MMP24 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MMP24-3717R Recombinant Rat MMP24 Protein Mammalian Cell His
Rat MMP24-3373R-B Recombinant Rat MMP24 Protein Pre-coupled Magnetic Beads HEK293
Rat MMP24-3373R Recombinant Rat MMP24 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

MMP24 involved in several pathways and played different roles in them. We selected most pathways MMP24 participated on our site, such as Activation of Matrix Metalloproteinases, Degradation of the extracellular matrix, Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMP24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activation of Matrix MetalloproteinasesMMP17;MMP13;MMP10;TIMP2;MMP24;MGC174155;TIMP2B;TIMP2A;CTRB1
Degradation of the extracellular matrixADAMTS4;ELANE;COL19A1;TPSAB1;CAPNS1;MMP15;CTSL2;LOC100686744;COL23A1
Extracellular matrix organizationADAMTS8;LAMB1B;COL11A1B;ABHD1;LRP4;COL15A1B;BMP1A;KLK7;P3H2
Matrix MetalloproteinasesMMP23B;BSG;MMP15;MMP28;MMP27;MMP8;MMP19;MMP20;MMP26

MMP24 has several biochemical functions, for example, cadherin binding, calcium ion binding, enzyme activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MMP24 itself. We selected most functions MMP24 had, and list some proteins which have the same functions with MMP24. You can find most of the proteins on our site.

Function Related Protein
cadherin bindingOLFM4;CD2AP;CTNNA2;JUPA;NDRG1;TRPC4;FXYD5;TBC1D2;CDK5R1
calcium ion bindingFBN1;AIF1;ESYT2;CALML5;SYTL4;VSNL1A;MACF1;PVALB8;DGKA
enzyme activator activityDCP1A;PITRM1;PRKCD;PRKCE;DBNL;HSPB2;SEC14L2;SFTPBB;MGST2
metalloendopeptidase activityADAM9;PAPPAA;THOP1;ADAM32;MEP1A.1;ADAM5P;ADAM8;C6AST3;MMP14B
zinc ion bindingNRAP;KDM5B;KDM2AA;SKI;TRIM109;KAT6B;LONRF2;MIB2;ADAMTS15

MMP24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMP24 here. Most of them are supplied by our site. Hope this information will be useful for your research of MMP24.

Gorasp2

Gene Family

MMPs

Research Area

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