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Official Full Name matrix metallopeptidase 24 (membrane-inserted)
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. [provided by RefSeq, Jul 2008]
Synonyms MMP24; matrix metallopeptidase 24 (membrane-inserted); MMP25; MMP-24; MT5MMP; MTMMP5; MT-MMP5; MT5-MMP; MT-MMP 5; matrix metalloproteinase-24; membrane-type 5 matrix metalloproteinase; membrane-type matrix metalloproteinase 5; membrane-type-5 matrix metalloproteinase; matrix metalloproteinase 24 (membrane-inserted);
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • Myc
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MMP24-610H Recombinant Human MMP24, Catalytic Domain, His-tagged E.coli His
    Mouse MMP24-2455M Recombinant Mouse MMP24 Protein (42-575 aa), His-Myc-tagged E.coli His/Myc
    Mouse MMP24-9920M Recombinant Mouse MMP24 Protein Mammalian Cell His
    Rat MMP24-3717R Recombinant Rat MMP24 Protein Mammalian Cell His

    mmp24 involved in several pathways and played different roles in them. We selected most pathways mmp24 participated on our site, such as Activation of Matrix Metalloproteinases, Degradation of the extracellular matrix, Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with mmp24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of Matrix Metalloproteinases MMP13; TIMP2; CMA1; FURINB; CTSG; MMP17; TIMP2B; CTSK; MGC174155; MMP10
    Degradation of the extracellular matrix ADAM15; ADAMTS1; TLL1; MMP8; ADAMTS4; CTSL1; FURINA; COL25A1; CTSS; ACAN
    Extracellular matrix organization TLDC2; CEACAM8; PCOLCE2; COL28A1; LAMB1B; MMP17; TIMP2B; MATN4; LOXL4; COL17A1
    Matrix Metalloproteinases MMP28; MMP26; MMP10; MMP17; MMP12; TIMP4; MMP19; MMP23B; MMP25; MMP27

    mmp24 has several biochemical functions, for example, cadherin binding, calcium ion binding, enzyme activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by mmp24 itself. We selected most functions mmp24 had, and list some proteins which have the same functions with mmp24. You can find most of the proteins on our site.

    Function Related Protein
    cadherin binding PSEN1; PROM1; CTNNA2; MMP24; P2RX4; Fert2; FXYD5; OLFM4; CD2AP; AKAP5
    calcium ion binding MEX3B; EEF2K; EFHA1; PRSS3; SRR; GCA; FKBP9; THBS4A; C1rb; SLC25A25B
    enzyme activator activity DBNL; PSAPL1; CASP9; PRKCD; ALOX5AP; ARL1; DCP1B; DNMT3L; SAE1; GM1679
    metalloendopeptidase activity MIPEP; ADAM32; MMP1A; BMP1A; ADAM8A; ECE2; C6AST1; PITRM1; OSGEPL1; UQCRC1
    zinc ion binding MT1; CPDB; NEURL1AA; ADAMTS9; ZCCHC2; TRIM3B; MDM2; SYVN1; BAZ2A; SRSF7B

    mmp24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with mmp24 here. Most of them are supplied by our site. Hope this information will be useful for your research of mmp24.


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