"TNFRSF1A" Related Products

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Recombinant Human Tumor Necrosis Factor Receptor Type 1, His Tag

Cat. No.: TNFRSF1A-4172H
Product Overview: TNFR1 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 161 amino acids fragment (41-201) having a molecular weight of 22.68kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. The TNFR1, His Tag is purified by proprietary chromatographic techniques.
Description: TNFR1 belongs to the TNF-receptor superfamily. TNFR1 is a receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. There are 2 types of soluble TNF receptors: sTNFR-I and sTNFR-II, which act to neutralize the biological activities of TNF alpha and TNF beta. The levels of these soluble receptors seem to increase as a result of shedding of the extracellular domains of the membrane bound receptors. TNF-a, TNFR1 and TNFR2 have roles in cellular differentiation. TNFR1 and TNFR2 function in cell type-specific renal injury.
Source: Human
Host: Escherichia Coli.
Form: TNFR1 His Tag protein is supplied in 1xPBS, 50% glycerol.
Purity: Greater than 95.0% as determined by SDS-PAGE.
Physical Appearance: Sterile Filtered clear solution.
Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Gene Name: TNFRSF1A tumor necrosis factor receptor superfamily, member 1A [ Homo sapiens ]
Official Symbol: TNFRSF1A
Synonyms: TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A; FPF; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55; MGC19588; tumor necrosis factor binding protein 1; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor type 1; tumor necrosis factor-alpha receptor
Gene ID: 7132
mRNA Refseq: NM_001065
Protein Refseq: NP_001056
MIM: 191190
UniProt ID: P19438
Chromosome Location: 12p13.2
Pathway: Adipocytokine signaling pathway; Alzheimer"s disease; Amyotrophic lateral sclerosis (ALS); Apoptosis; Cytokine-cytokine receptor interaction; MAPK signaling pathway; MAPK signaling pathway; Apoptosis
Function: protein complex binding; receptor activity; tumor necrosis factor receptor activity

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