Tnfrsf12a Protein


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Official Full Name tumor necrosis factor receptor superfamily, member 12A
Background Fibroblast growth factor-inducible 14 (Fn14) is the receptor for Tweak, a member of the TNF receptor family. It was first described as a weak inducer of apoptosis in some cell types. It is thought to promote angiogenesis and the proliferation of endothelial cells as well as modulating cellular adhesion to matrix proteins. Fn14 is highly expressed in glioma and some cancer cases of breast, pancreas, and liver. Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins
Synonyms TNFRSF12A; tumor necrosis factor receptor superfamily, member 12A; tumor necrosis factor receptor superfamily member 12A; CD266; FN14; TweakR; tweak-receptor; FGF-inducible 14; type I transmembrane protein Fn14; fibroblast growth factor-inducible immediate-early response protein 14; tumor necrosis factor receptor superfamily, member 12
    • Species :
    • Human
    • Mouse
    • Rhesus monkey
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Human Cells
    • Tag :
    • Fc
    • Fc-His(C-ter)
    • hIgG1
    • hIgG4
    • His
    • GST
    • N/A
    • N-His&GST
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TNFRSF12A-221H Active Recombinant Human TNFRSF12A Protein, Fc-tagged HEK293 Fc Inquiry
    Human TNFRSF12A-41H Active Recombinant Human Fn-14, Fc-tagged HEK293 Fc Inquiry
    Human TNFRSF12A-709H Active Recombinant Human TNFRSF12A, Fc-tagged, Biotinylated Human Cell Fc Inquiry
    Mouse Tnfrsf12a-42M Active Recombinant Mouse Fn-14, Fc-tagged HEK293 Fc Inquiry
    Human TNFRSF12A-2125H Recombinant Human TNFRSF12A, Fc Chimera HEK293 Fc Inquiry
    Human TNFRSF12A-30125TH Recombinant Human TNFRSF12A, Fc-tagged HEK293 Fc Inquiry
    Human TNFRSF12A-30127TH Recombinant Human TNFRSF12A, Fc-tagged E.coli Fc Inquiry
    Human TNFRSF12A-582H Recombinant Human TNFRSF12A protein E.coli N/A Inquiry
    Human TNFRSF12A-7734H Recombinant Human TNFRSF12A protein, His & GST-tagged E.coli His/GST Inquiry
    Mouse Tnfrsf12a-2085M Recombinant Mouse Tnfrsf12a, Fc Chimera HEK293 Fc Inquiry
    Rhesus monkey TNFRSF12A-1645R Recombinant Rhesus Monkey TNFRSF12A Protein HEK293 N/A Inquiry
    Rhesus monkey TNFRSF12A-1646R Recombinant Rhesus Monkey TNFRSF12A Protein, hIgG1-tagged HEK293 hIgG1 Inquiry
    Rhesus monkey TNFRSF12A-1647R Recombinant Rhesus Monkey TNFRSF12A Protein, hIgG4-tagged HEK293 hIgG4 Inquiry
    Human TNFRSF12A-1560HCL Recombinant Human TNFRSF12A cell lysate Human Cell N/A Inquiry
    Human TNFRSF12A-151H Recombinant Human TNFRSF12A Protein, DYKDDDDK-tagged Human Cells DYKDDDDK Inquiry
    Human TNFRSF12A-312H Recombinant Active Human TNFRSF12A Protein (ECD), Fc-His-tagged(C-ter) HEK293 Fc-His(C-ter) Inquiry
    Human TNFRSF12A-441H Recombinant Human TNFRSF12A Protein, His&GST-tagged E.coli N-His&GST Inquiry

    Tnfrsf12a involved in several pathways and played different roles in them. We selected most pathways Tnfrsf12a participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Tnfrsf12a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IFNB; CCL27B; IL29; IL18RAP; CCR9; TNFRSF13C; CCR10; IL3RA; TNFSF9; TNFSF13B

    Tnfrsf12a has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Tnfrsf12a itself. We selected most functions Tnfrsf12a had, and list some proteins which have the same functions with Tnfrsf12a. You can find most of the proteins on our site.

    Function Related Protein
    protein binding HIST1H1E; CCHCR1; KCNS2; SKAP1; MYLIP; EDA2R; MYL6B; STX10; NDUFS7; ANKRD1

    Tnfrsf12a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Tnfrsf12a here. Most of them are supplied by our site. Hope this information will be useful for your research of Tnfrsf12a.

    TNFSF12; SLC30A2; TRAF2; BIRC2; fliN

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