|Official Full Name||tumor necrosis factor receptor superfamily, member 12A|
|Background||Fibroblast growth factor-inducible 14 (Fn14) is the receptor for Tweak, a member of the TNF receptor family. It was first described as a weak inducer of apoptosis in some cell types. It is thought to promote angiogenesis and the proliferation of endothelial cells as well as modulating cellular adhesion to matrix proteins. Fn14 is highly expressed in glioma and some cancer cases of breast, pancreas, and liver. Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins|
|Synonyms||TNFRSF12A; tumor necrosis factor receptor superfamily, member 12A; tumor necrosis factor receptor superfamily member 12A; CD266; FN14; TweakR; tweak-receptor; FGF-inducible 14; type I transmembrane protein Fn14; fibroblast growth factor-inducible immediate-early response protein 14; tumor necrosis factor receptor superfamily, member 12|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
tnfrsf12a involved in several pathways and played different roles in them. We selected most pathways tnfrsf12a participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with tnfrsf12a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cytokine-cytokine receptor interaction||IL6ST; BMPR2; BMP2; PRL2; IFNE; TNFRSF13B; CSF2RA; CXCR4B; CCL15; IFNA21|
tnfrsf12a has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by tnfrsf12a itself. We selected most functions tnfrsf12a had, and list some proteins which have the same functions with tnfrsf12a. You can find most of the proteins on our site.
|protein binding||RNPS1; CETN1; CDC42EP5; MYO15; TRAF3IP2; RAB26; BTG2; FOXD3; TADA3; PSMF1|
tnfrsf12a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with tnfrsf12a here. Most of them are supplied by our site. Hope this information will be useful for your research of tnfrsf12a.
TNFSF12; SLC30A2; TRAF2; BIRC2; fliN