TNFRSF21

  • Official Full Name

    tumor necrosis factor receptor superfamily, member 21

  • Overview

    This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013]
  • Synonyms

    TNFRSF21; tumor necrosis factor receptor superfamily, member 21; DR6; CD358; BM-018; tumor necrosis factor receptor superfamily member 21; death receptor 6; TNFR-related death receptor 6;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Rabbit
  • Sf21 Insect Cell
  • C
  • Fc
  • hFc
  • His
  • Fc|His
  • His (Fc)
  • Avi
  • His|HIgG
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TNFRSF21-599H Active Recombinant Human TNFRSF21, Fc-tagged, Biotinylated Human Cell Fc
Human TNFRSF21-687H Active Recombinant Human TNFRSF21 protein(Met1-Leu350), hFc-tagged HEK293 C-hFc Met1-Leu350
Human TNFRSF21-1038H Active Recombinant Human TNFRSF21 Protein, Fc Chimera Sf21 Insect Cell Fc
Human TNFRSF21-28132TH Recombinant Human TNFRSF21, Fc-tagged Fc
Human TNFRSF21-1604H Recombinant Human TNFRSF21 Sf21 Insect Cell N/A
Human TNFRSF21-3321H Recombinant Human TNFRSF21, His-tagged E.coli His C-291aa
Human TNFRSF21-228H Recombinant Human TNFRSF21, Fc-tagged HEK293 Fc
Human TNFRSF21-2236H Active Recombinant Human TNFRSF21 protein, His-tagged HEK293 His Met1-Leu350
Human TNFRSF21-50H Recombinant Human TNFRSF21, Fc Chimera HEK293 Fc
Human TNFRSF21-688H Recombinant Human TNFRSF21 protein HEK293 N/A Met1-Leu350
Human TNFRSF21-943H Recombinant Human TNFRSF21 Protein, His-tagged HEK293 His
Human TNFRSF21-2977HCL Recombinant Human TNFRSF21 cell lysate Human Cell N/A
Human TNFRSF21-206H Recombinant Human TNFRSF21 Protein, Fc-tagged HEK293 Fc 655
Human TNFRSF21-001H Recombinant Human TNFRSF21 Protein, hIgG-His-tagged Insect Cell His/HIgG
Human TNFRSF21-052H Recombinant Human TNFRSF21 Protein, C-His-tagged E.coli C-His
Human TNFRSF21-3601H Recombinant Human TNFRSF21 protein, His-SUMO-tagged E.coli His-SUMO 371-655aa
Human TNFRSF21-4200H Recombinant Human TNFRSF21 Protein (Met1-Leu350), C-His tagged Mammalian cells C-His Met1-Leu350
Human CAB11620RH Rabbit Monoclonal Antibody to Human Tumor Necrosis Factor Receptor Superfamily, Member 21 Rabbit N/A
Human TNFRSF21-5812H Recombinant Human TNFRSF21 Protein (Gln42-Leu350), C-Fc tagged Mammalian cells C-Fc Gln42-Leu350
Mouse Tnfrsf21-867M Active Recombinant Mouse Tnfrsf21 Protein, Fc Chimera Mammalian cells Fc
Mouse Tnfrsf21-1066M Recombinant Mouse Tnfrsf21 protein, His-tagged E.coli His Lys406~His605 (Accession # Q9EPU5)
Mouse Tnfrsf21-3281M Active Recombinant Mouse Tnfrsf21 protein(Met1-His349), His-tagged HEK293 C-His Met1-His349
Mouse TNFRSF21-2424MCL Recombinant Mouse TNFRSF21 cell lysate Human Cell N/A
Mouse Tnfrsf21-6701M Recombinant Mouse Tnfrsf21 Protein (Gln42-His349), C-His and Fc tagged Mammalian cells C-His and Fc Gln42-His349
Mouse Tnfrsf21-2033M Recombinant Mouse Tnfrsf21 Protein, Fc/His-tagged HEK293 Fc/His
Mouse Tnfrsf21-121M Recombinant Mouse Tnfrsf21 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Tnfrsf21-121M-B Recombinant Mouse Tnfrsf21 Protein Pre-coupled Magnetic Beads HEK293
Rat TNFRSF21-6199R Recombinant Rat TNFRSF21 Protein Mammalian Cell His
Rat TNFRSF21-5856R-B Recombinant Rat TNFRSF21 Protein Pre-coupled Magnetic Beads HEK293
Rat TNFRSF21-5856R Recombinant Rat TNFRSF21 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TNFRSF21-363R Recombinant Rat TNFRSF21 protein(Met1-His349), hFc-tagged HEK293 C-hFc Met1-His349
Cynomolgus Monkey TNFRSF21-1230C Active Recombinant Cynomolgus TNFRSF21 Protein, His-tagged HEK293 His
Homo sapiens (Human) RFL22666HF Recombinant Full Length Human Tumor Necrosis Factor Receptor Superfamily Member 21(Tnfrsf21) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (42-655)
Zebrafish TNFRSF21-3819Z Recombinant Zebrafish TNFRSF21 Mammalian Cell His
Chicken TNFRSF21-2777C Recombinant Chicken TNFRSF21 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • TNFRSF21 Related Signal Pathway

TNFRSF21 involved in several pathways and played different roles in them. We selected most pathways TNFRSF21 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNFRSF21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionFLT4;IL12BA;PRL;GH2;CXCR4;IFNA1;IFNPHI1;BMP7B;IFNA2

TNFRSF21 has several biochemical functions, for example, protein binding, tumor necrosis factor-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TNFRSF21 itself. We selected most functions TNFRSF21 had, and list some proteins which have the same functions with TNFRSF21. You can find most of the proteins on our site.

Function Related Protein
protein bindingSH2D1B;STK40;RPP25;AMHR2;DNER;SFMBT1;MAP3K7;KAT6B;MKI67
tumor necrosis factor-activated receptor activityTNFRSF1B;HDR;TNFRSF11B;TNFRSF25;TNFRSF10C;TNFRSF10A;Tnfrsf26;FAS;RELT

TNFRSF21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNFRSF21 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNFRSF21.

APP; TRADD; STX11; MATR3; WASH2P; polg_hcvjf_rna

Gene Family

TNF

Research Area

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