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Official Full Name tumor necrosis factor receptor superfamily, member 10a
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Synonyms TNFRSF10A; tumor necrosis factor receptor superfamily, member 10a; DR4; APO2; CD261; TRAILR1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; TRAIL-R1; TRAIL receptor 1; death receptor 4; cytotoxic TRAIL receptor; TNF-related apoptosis-inducing ligand receptor 1; tumor necrosis factor receptor superfamily member 10a variant 2;
    • Species :
    • Human
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Sf21 Insect Cell
    • Tag :
    • Fc
    • Fc Chimera
    • His
    • His-Avi
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TNFRSF10A-112H Recombinant Human TNFRSF10A E.coli N/A
    Human TNFRSF10A-212H Recombinant Human TNFRSF10A protein, His-Avi-tagged HEK293 His-Avi
    Human TNFRSF10A-212HB Recombinant Human TNFRSF10A protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
    Human TNFRSF10A-2180HCL Recombinant Human TNFRSF10A cell lysate Human Cell N/A
    Human TNFRSF10A-248H Recombinant Human TNFRSF10A, Fc Chimera Sf21 Insect Cell Fc Chimera
    Human TNFRSF10A-249H Recombinant Human TNFRSF10A, Fc Chimera CHO Fc Chimera
    Human TNFRSF10A-27024TH Recombinant Human TNFRSF10A, Fc-tagged Fc
    Human TNFRSF10A-312H Recombinant Human TNFRSF10A Protein E.coli N/A
    Human TNFRSF10A-3131H Recombinant Human TNFRSF10A, Fc tagged Human Cell Fc
    Human TNFRSF10A-3168H Recombinant Human TNFRSF10A, His tagged Human Cell His
    Human TNFRSF10A-49H Recombinant Human TRAIL-R1, Fc Chimera HEK293 Fc
    Human TNFRSF10A-524H Recombinant Human TNFRSF10A, Fc-tagged HEK293 Fc
    Human TNFRSF10A-597H Recombinant Human TNFRSF10A, Fc-tagged, Biotinylated Human Cell Fc
    Human TNFRSF10A-883H Recombinant Human TNFRSF10A, Fc-His tagged Human Cell Fc/His

    tnfrsf10a involved in several pathways and played different roles in them. We selected most pathways tnfrsf10a participated on our site, such as Cytokine-cytokine receptor interaction, Apoptosis, Natural killer cell mediated cytotoxicity, which may be useful for your reference. Also, other proteins which involved in the same pathway with tnfrsf10a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IL5; CNTFR; ACKR3B; CXCL3; IL2RA; Il2; VEGFAA; LOC100033925; CCR8L; PRLR
    Natural killer cell mediated cytotoxicity TNFRSF10D; PTPN11; NFATC1; FASLG; PPP3R2; IFNGR2; FCGR3B; Ifna11; ITGAL; ULBP1
    Measles IRF3; PIK3R5; SLAMF1; OAS1A; CCND3; AKT1; IFNA8; IFNA5; IL12B; STAT1
    Influenza A IKBKE; GSK3B; IFNA6; CXCL10; NXT1; IFNA16; MAPK10; CCL2; PML; STAT1

    tnfrsf10a has several biochemical functions, for example, TRAIL binding, death receptor activity, protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by tnfrsf10a itself. We selected most functions tnfrsf10a had, and list some proteins which have the same functions with tnfrsf10a. You can find most of the proteins on our site.

    Function Related Protein
    TRAIL binding TNFRSF10A; TNFRSF10B; Tnfrsf22; TNFRSF10C; TNFRSF10D
    death receptor activity NGFR; TNFRSF10A
    protease binding CFLAR; CAST; Serpina1b; TIMP2; UBC; SERPINE1; CRADD; TYSND1; PEO1; SERPINB9
    protein binding PIWIL1; FSHB; ACLY; GNAS; PCP4; NUAK1; DSN1; FOXL2; PDPK1; IFIT1
    receptor activity P2RY2; NRXN3; GRIA2A; GRIA2B; CD1D; TLR3; CD93; KLRC4-KLRK1; LILRB4; CADM1A
    transcription factor binding RELA; TFDP1A; NFKBIA; FOXO4; HDAC7; HES4; PIAS2; HMGA1; RBL1; GATA6
    tumor necrosis factor-activated receptor activity CD40; TNFRSF1B; NGFR; EDA2R; TNFRSF14; TNFRSF18; TNFRSF10C; TNFRSF21; NGFRB; TNFRSF10D

    tnfrsf10a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with tnfrsf10a here. Most of them are supplied by our site. Hope this information will be useful for your research of tnfrsf10a.



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