Tnfrsf10b Protein

Tnfrsf10b

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Tnfrsf10b

Official Full Name tumor necrosis factor receptor superfamily, member 10b
Background The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Synonyms TNFRSF10B; tumor necrosis factor receptor superfamily, member 10b; DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; tumor necrosis factor receptor superfamily member 10B; Fas-like protein; death receptor 5; cytotoxic TRAIL receptor-2; TNF receptor superfamily member 10b; apoptosis inducing receptor TRAIL-R2; apoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; death domain containing receptor for TRAIL/Apo-2L; tumor necrosis factor receptor-like protein ZTNFR9; p53-regulated DNA damage-inducible cell death receptor(killer);
    • Species :
    • Chicken
    • Homo sapiens (Human)
    • Human
    • Mouse
    • Rat
    • Rhesus monkey
    • Source :
    • E.coli
    • E.coli expression system
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • Sf21 Insect Cell
    • Tag :
    • Avi-His
    • Fc
    • Fc/His
    • His
    • hIgG1
    • hIgG4
    • Avi
    • GST
    • His-Avi
    • HlgG1 Fc
    • human
    • IgG1
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    • N-His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TNFRSF10B-460H Active Recombinant Human TNFRSF10B, Fc Chimera HEK293 Fc Inquiry
    Human TNFRSF10B-518H Active Recombinant Human TNFRSF10B E.coli N/A Inquiry
    Human TNFRSF10B-598H Active Recombinant Human TNFRSF10B, Fc-tagged, Biotinylated Human Cell Fc Inquiry
    Human TNFRSF10B-2350H Recombinant Human TNFRSF10B, His tagged Human Cell His Inquiry
    Human TNFRSF10B-27023TH Recombinant Human TNFRSF10B, Fc-tagged HEK293 Fc Inquiry
    Human TNFRSF10B-28127TH Recombinant Human TNFRSF10B, Fc-tagged Fc Inquiry
    Human TNFRSF10B-28129TH Recombinant Human TNFRSF10B, Fc-tagged HEK293 Fc Inquiry
    Human TNFRSF10B-28130TH Recombinant Human TNFRSF10B, Fc-tagged Fc Inquiry
    Human TNFRSF10B-309H Recombinant Human TNFRSF10B Protein, His-tagged HEK293 His Inquiry
    Human TNFRSF10B-310H Recombinant Human TNFRSF10B Protein, Fc/His-tagged HEK293 Fc/His Inquiry
    Human TNFRSF10B-311H Recombinant Human TNFRSF10B protein E.coli N/A Inquiry
    Human TNFRSF10B-51H Recombinant Human TRAIL-R2, Fc Chimera HEK293 Fc Inquiry
    Human TNFRSF10B-56H Recombinant Human TNFRSF10B protein, Fc-tagged, FITC-labeled HEK293 Fc Inquiry
    Human TNFRSF10B-7761H Recombinant Human TNFRSF10B protein, His & GST-tagged E.coli His/GST Inquiry
    Human TNFRSF10B-884H Recombinant Human TNFRSF10B, Fc-His tagged Human Cell Fc/His Inquiry
    Mouse Tnfrsf10b-178M Recombinant Mouse Tnfrsf10b Sf21 Insect Cell N/A Inquiry
    Mouse Tnfrsf10b-3292M Recombinant Mouse Tnfrsf10b, His tagged Human Cell His Inquiry
    Mouse Tnfrsf10b-3321M Recombinant Mouse Tnfrsf10b, Fc-His tagged Human Cell Fc/His Inquiry
    Mouse Tnfrsf10b-7762M Recombinant Mouse Tnfrsf10b protein, His-tagged E.coli His Inquiry
    Mouse Tnfrsf10b-7763M Recombinant Mouse Tnfrsf10b protein, His-tagged E.coli His Inquiry
    Rhesus monkey TNFRSF10B-1637R Recombinant Rhesus Monkey TNFRSF10B Protein HEK293 N/A Inquiry
    Rhesus monkey TNFRSF10B-1638R Recombinant Rhesus Monkey TNFRSF10B Protein, hIgG1-tagged HEK293 hIgG1 Inquiry
    Rhesus monkey TNFRSF10B-1639R Recombinant Rhesus Monkey TNFRSF10B Protein, hIgG4-tagged HEK293 hIgG4 Inquiry
    Chicken TNFRSF10B-5691C Recombinant Chicken TNFRSF10B Mammalian Cell His Inquiry
    Human TNFRSF10B-2829HCL Recombinant Human TNFRSF10B cell lysate Human Cell N/A Inquiry
    Mouse TNFRSF10B-2397MCL Recombinant Mouse TNFRSF10B cell lysate Human Cell N/A Inquiry
    Homo sapiens (Human) RFL25566HF Recombinant Full Length Human Tumor Necrosis Factor Receptor Superfamily Member 10B(Tnfrsf10B) Protein, His-Tagged E.coli expression system His Inquiry
    Human TNFRSF10B-2136H Recombinant Human TNFRSF10B Protein, His-tagged E.coli N-His Inquiry
    Human TNFRSF10B-2350HAF488 Recombinant Human TNFRSF10B Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
    Human TNFRSF10B-2350HAF555 Recombinant Human TNFRSF10B Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
    Human TNFRSF10B-2350HAF647 Recombinant Human TNFRSF10B Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
    Human TNFRSF10B-2350HF Recombinant Human TNFRSF10B Protein, His-tagged, FITC conjugated HEK293 His
    Rat Tnfrsf10b-2745R Recombinant Rat Tnfrsf10b Protein, His-tagged E.coli N-His Inquiry
    Mouse Tnfrsf10b-3292MAF488 Recombinant Mouse Tnfrsf10b Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
    Mouse Tnfrsf10b-3292MAF555 Recombinant Mouse Tnfrsf10b Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
    Mouse Tnfrsf10b-3292MAF647 Recombinant Mouse Tnfrsf10b Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
    Mouse Tnfrsf10b-3292MF Recombinant Mouse Tnfrsf10b Protein, His-tagged, FITC conjugated HEK293 His
    Mouse Tnfrsf10b-3293M Recombinant Mouse Tnfrsf10b(Asn53-Ser177) Protein, C-Avi-6*His-tagged, Biotinylated HEK293 Avi-His Inquiry
    Mouse Tnfrsf10b-3321MAF488 Recombinant Mouse Tnfrsf10b Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Fc/His
    Mouse Tnfrsf10b-3321MAF555 Recombinant Mouse Tnfrsf10b Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Fc/His
    Mouse Tnfrsf10b-3321MAF647 Recombinant Mouse Tnfrsf10b Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Fc/His
    Mouse Tnfrsf10b-3321MF Recombinant Mouse Tnfrsf10b Protein, Fc/His-tagged, FITC conjugated HEK293 Fc/His
    Human TNFRSF10B-884HAF488 Recombinant Human TNFRSF10B Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Fc/His
    Human TNFRSF10B-884HAF555 Recombinant Human TNFRSF10B Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Fc/His
    Human TNFRSF10B-884HAF647 Recombinant Human TNFRSF10B Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Fc/His
    Human TNFRSF10B-884HF Recombinant Human TNFRSF10B Protein, Fc/His-tagged, FITC conjugated HEK293 Fc/His
    Human TNFRSF10B-1148H Recombinant Human TNFRSF10B Protein (Met1-Glu182), HlgG1 Fc-tagged HEK293 HlgG1 Fc Inquiry
    Human TNFRSF10B-1435H Recombinant Human TNFRSF10B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Human TNFRSF10B-1999H Recombinant Human TNFRSF10B Protein, MYC/DDK-tagged HEK293 Myc/DDK Inquiry
    Human TNFRSF10B-2350HB Recombinant Human TNFRSF10B protein, His-tagged, Biotinylated HEK293 His Inquiry
    Human TNFRSF10B-377H Recombinant Human TNFRSF10B protein, Fc-tagged HEK293 human/IgG1/Fc Inquiry
    Human TNFRSF10B-599H Recombinant Human TNFRSF10B Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi Inquiry
    Human TNFRSF10B-763H Recombinant Human TNFRSF10B protein, His-Avi-tagged HEK293 His-Avi Inquiry
    Mouse Tnfrsf10b-6544M Recombinant Mouse Tnfrsf10b Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry

    Tnfrsf10b involved in several pathways and played different roles in them. We selected most pathways Tnfrsf10b participated on our site, such as Cytokine-cytokine receptor interaction, p signaling pathway, Apoptosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Tnfrsf10b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction TNFSF11; CD27; IL23; PRL; TNFSF13; CCR8; TGFB1A; CRFB16; BMP7; IL21R.1
    p signaling pathway RCHY1; CASP3A; CCNB3; APAF1; TSC2; TP73; BAI1; CYCS; CCND2; CCNE1
    Apoptosis PANK1A; RELA; STK24; BOK; Fasl; CASP12; Gzmg; BIRC2; JUN; PRKAR1A
    Natural killer cell mediated cytotoxicity HRAS; KIR2DS3; SAMD3; VAV3; ITGB2; PTK2B; SHC4; FCGR3; FCGR3A; SYK
    Measles CCND1; IFNA14; IL1A; DDX58; MAP3K7; STAT5B; HSPA8; IFNA1; FCGR2B; CCND2
    Influenza A TNFRSF10B; TBK1; TNFSF10; IRAK4; FAS; MAPK3; HSPA1L; HLA-DRB3; SLC25A6; HLA-DPA1

    Tnfrsf10b has several biochemical functions, for example, TRAIL binding, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Tnfrsf10b itself. We selected most functions Tnfrsf10b had, and list some proteins which have the same functions with Tnfrsf10b. You can find most of the proteins on our site.

    Function Related Protein
    TRAIL binding TNFRSF10D; TNFRSF10A; TNFRSF10B; TNFRSF10C; Tnfrsf22
    protein binding ACSS1; TMA16; ZNF136; RBM3; ABCD1; KATNAL1; KCNE1; C6orf211; TSKS; CAMP
    receptor activity CSF2RA; BTLA; GRIN1B; LRP2; LILRB3; VMN1R46; PVRL1A; TLR1; PVRL3B; TLR3
    tumor necrosis factor-activated receptor activity Tnfrsf26; TNFRSF10D; NGFR; RELT; TNFRSF14; TNFRSF9A; CD27; LTBR; HDR; TNFRSFA

    Tnfrsf10b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Tnfrsf10b here. Most of them are supplied by our site. Hope this information will be useful for your research of Tnfrsf10b.

    TNFSF10

    Meng, XW; Koh, BD; et al. Poly(ADP-ribose) Polymerase Inhibitors Sensitize Cancer Cells to Death Receptor-mediated Apoptosis by Enhancing Death Receptor Expression. JOURNAL OF BIOLOGICAL CHEMISTRY 289:20543-20558(2014).
    Seirafian, S; Prod'homme, V; et al. Human cytomegalovirus suppresses Fas expression and function. JOURNAL OF GENERAL VIROLOGY 95:933-939(2014).

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