TNFRSF10D
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Official Full Name
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain -
Overview
The tumor necrosis factor receptor family, which includes TNF-RI, Fas, DR3, DR4, DR5, and DR6, plays an important role in the regulation of apoptosis in various physiological systems (1,2). The receptors are activated by a family of cytokines that include -
Synonyms
TNFRSF10D;tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain;tumor necrosis factor receptor superfamily member 10D;CD264;DcR2;TRAILR4;TRUNDD;TRAIL receptor 4;decoy receptor 2;decoy with truncated death domai
Recombinant Proteins
- Human
- Rhesus macaque
- Cynomolgus
- HEK293
- Human Cells
- Mammalian Cells
- Yeast
- His
- Fc
- Non
- Avi
Involved Pathway
TNFRSF10D involved in several pathways and played different roles in them. We selected most pathways TNFRSF10D participated on our site, such as Cytokine-cytokine receptor interaction,Apoptosis,Natural killer cell mediated cytotoxicity, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNFRSF10D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Measles | IFNA14,PIK3CB,IFNA12,OAS2,MAP3K7,IFNA2,MAVS,CBLB,IFNG,STAT5A |
| Apoptosis | YWHAQ,BIRC8,IRF4A,CASP8,CLSPN,DAPK3,PRKACAA,DBNLB,BIRC2,AIFM1 |
| Natural killer cell mediated cytotoxicity | IFNAR1,IFNA21,IFNGR2,PPP3CB,GM-CSF,SHC2,GRB2,KLRA8,PTPN11,IFNA8 |
| Cytokine-cytokine receptor interaction | CCL20,CCL20B,PF4V1,LTBR,CSF1,TNFSF11,GHRA,TNFRSF9,LEPR,TGFB1A |
| Influenza A | IL6,FAS,IFNA7,PIK3CG,VDAC1,STAT1,TMPRSS4,MAVS,IFNA16,DDX58 |
Protein Function
TNFRSF10D has several biochemical functions, for example, TRAIL binding,transmembrane signaling receptor activity,tumor necrosis factor-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TNFRSF10D itself. We selected most functions TNFRSF10D had, and list some proteins which have the same functions with TNFRSF10D. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| TRAIL binding | TNFRSF10C,TNFRSF10B,TNFRSF10A,Tnfrsf22 |
| tumor necrosis factor-activated receptor activity | TNFRSF1A,LTBR,TNFRSF4,TNFRSF6B,TNFRSF14,TNFRSF11B,EDA2R,TNFRSFA,TNFRSF9,CD40 |
| transmembrane signaling receptor activity | OR4N4,EDAR,CD79A,KIR2DL4,CALCRLA,THBD,CD27,CLEC2D,EGFR,OR4D6 |
Interacting Protein
TNFRSF10D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNFRSF10D here. Most of them are supplied by our site. Hope this information will be useful for your research of TNFRSF10D.
TNFSF10;q6zrv1_human;PFAS;WDR1;CSDE1;SMC2;MTHFD1;IMPDH2;PLS3;MIF;DARS;GSPT1;VARS;CALR;TKT;KIF5B
TNFRSF10D Related Signal Pathway
Resources
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References
- Li, ZB; Guo, XW; et al. Methylation profiling of 48 candidate genes in tumor and matched normal tissues from breast cancer patients. BREAST CANCER RESEARCH AND TREATMENT 149:767-779(2015).
- Ratzinger, G; Mitteregger, S; et al. Association of TNFRSF10D DNA-Methylation with the Survival of Melanoma Patients. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 15:11984-11995(2014).
