Recombinant Human TNFRSF17
Cat.No. : | TNFRSF17-2604H |
Product Overview : | Recombinant Human Tumor Necrosis Factor Receptor Superfamily, Member 17 produced inE.Coliis a single, non-glycosylated, polypeptide chain containing 50 amino acids and having a molecular mass of 5.3 kDa. The TNFRSF17 is purified by standard chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | TNFRSF17-2604H |
Description : | TNFRSF17 is a receptor for tnfsf13b/blys/baff and tnfsf13/april. TNFRSF17 promotes b-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 activates nf-kappa-b and jnk. TNFRSF17 is a member of the TNF-receptor superfamily. TNFRSF17 is expressed in mature B lymphocytes, and is invloved in B cell development and autoimmune response. TNFRSF17 specifically binds to the tumor TNFSF13B/TALL-1/BAFF, which causes NF-kappaB and MAPK8/JNK activation. TNFRSF17 binds to a variety of TRAF family members, and therefore transduces signals for cell survival and proliferation. TNFRSF17 is a type III membrane protein having 1 extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. |
Source : | E.Coli. |
Purity : | Greater than 98% as determined by SDS-PAGE. |
Sequence : | AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA. |
Physical Appearance : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Formulation : | 1mg of TNFRSF17 Human contains 20mM PBS, pH-7.4, and 130mM NaCl. |
Solubility : | It is recommended to reconstitute the lyophilized TNFRSF17 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
Storage : | Lyophilized TNFRSF17 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TNFRSF17 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze/thaw cycles. |
Gene Name : | TNFRSF17 tumor necrosis factor receptor superfamily, member 17 [ Homo sapiens ] |
Synonyms : | TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF17; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B-cell maturation protein |
Gene ID : | 608 |
mRNA Refseq : | NM_001192 |
Protein Refseq : | NP_001183 |
MIM : | 109545 |
UniProt ID : | Q02223 |
Chromosome Location : | 16p13.1 |
Pathway : | Cytokine-cytokine receptor interaction; Intestinal immune network for IgA production |
Function : | protein binding; receptor activity; tumor necrosis factor receptor activity |
Products Types
◆ Recombinant Protein | ||
TNFRSF17-240H | Active Recombinant Human TNFRSF17 Protein, His-Avi-tagged, Biotinylated | +Inquiry |
TNFRSF17-5253H | Recombinant Human TNFRSF17 Protein | +Inquiry |
TNFRSF17-100R | Recombinant Rhesus macaque TNFRSF17 Protein, Fc-tagged | +Inquiry |
TNFRSF17-322H | Active Recombinant Human TNFRSF17 Protein, LIgG2b Fc-tagged, low endotoxin | +Inquiry |
TNFRSF17-04H | Active Recombinant Human TNFRSF17 Protein, Fc-tagged, Atto 647N conjugated | +Inquiry |
◆ Lysates | ||
TNFRSF17-1489RCL | Recombinant Rat TNFRSF17 cell lysate | +Inquiry |
TNFRSF17-2593MCL | Recombinant Mouse TNFRSF17 cell lysate | +Inquiry |
TNFRSF17-1253CCL | Recombinant Cynomolgus TNFRSF17 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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