Recombinant Human TNFRSF17 Protein

Cat.No. : TNFRSF17-5253H
Product Overview : Recombinant Human TNFRSF17 Protein (5-54 domain) without tag was expressed in E. coli.
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Description : The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
Source : E. coli
Species : Human
Molecular Mass : Recombinant BCMA is a monomer protein consisting of 50 amino acid residue subunits, and migrates as an approximately 5 kDa protein under non-reducing and reducing conditions in SDS-PAGE.
AA Sequence : MLQMAGQCSQNEYFDSLLHACIPCQ LRCSSNTPPLTCQRYCNASVTNSVK GTNAILWTCL
Endotoxin : Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 1 ng/μg (1 EU/μg).
Purity : >95%, as determined by SDS-PAGE and HPLC
Storage : The lyophilized protein is stable for at least years from date of receipt at -20 centigrade. Upon reconstitution, this product can be stored in working aliquots at -20 centigrade for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Storage Buffer : Recombinant BCMA was lyophilized from a.2 μm filtered% acetonitrile, 1% TFA solutionpH.5.
Reconstitution : A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 1 mg/mL. This solution can then be diluted into other buffers.
Gene Name : TNFRSF17 TNF receptor superfamily member 17 [ Homo sapiens (human) ]
Official Symbol : TNFRSF17
Synonyms : TNFRSF17; TNF receptor superfamily member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B cell maturation antigen; B-cell maturation factor; B-cell maturation protein
Gene ID : 608
mRNA Refseq : NM_001192
Protein Refseq : NP_001183
MIM : 109545
UniProt ID : Q02223

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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