"EIF4EBP1" Related Products

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Recombinant Human EIF4EBP1

Cat. No.: EIF4EBP1-1397H
Product Overview: Recombinant Human EIF4EBP1 protein was expressed in E.coli and purified by using conventional chromatography techniques. MW = 14.7 kDa (138aa).
Description: eIF4E-BP1, also known as eukaryotic translation initiation factor 4E-binding protein 1, is a member of a family of translation repressor proteins. This protein regulates eukaryotic translation initiation factor 4E (eIF4E) activity by preventing its assembly into the eIF4F complex and mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Source: E.coli.
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSGGSSCSQT PSRAIPATRR VVLGDGVQLP PGDYSTTPGG TLFSTTPGGT RIIYDRKFLM ECRNSPVTKT PPRDLPTIPG VTSPSSDEPP MEASQSHLRN SPEDKRAGGE ESQFEMDI
Form: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol.
Purity: > 95% by SDS – PAGE.
Concentration: 1 mg/ml (determined by Bradford assay).
Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method).
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 [ Homo sapiens ]
Synonyms: EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; BP-1; 4EBP1; 4E-BP1; PHAS-I; MGC4316; eIF4E-binding protein 1; phosphorylated heat- and acid-stable protein regulated by insulin 1; Eukaryotic translation initiation factor 4E-binding protein 1
Gene ID: 1978
mRNA Refseq: NM_004095
Protein Refseq: NP_004086
MIM: 602223
UniProt ID: Q13541
Chromosome Location: 8p12
Pathway: Acute myeloid leukemia; ErbB signaling pathway; Insulin signaling pathway; mTOR signaling pathway
Function: eukaryotic initiation factor 4E binding; protein binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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