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Official Full Name eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
Background The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit. [provided by RefSeq, Jan 2010]
Synonyms EIF2S3; eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa; EIF2; EIF2G; eIF-2gA; EIF2gamma; eukaryotic translation initiation factor 2 subunit 3; eIF-2gX; eIF-2-gamma X; eukaryotic translation initiation factor 2G; eukaryotic translation initiation factor 2 subunit gamma X;
    • Species :
    • Chicken
    • Human
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EIF2S3-28379TH Recombinant Human EIF2S3 Wheat Germ N/A
    Human EIF2S3-3175H Recombinant Human EIF2S3 Protein, GST-tagged Wheat Germ GST
    Chicken EIF2S3-1407C Recombinant Chicken EIF2S3 Mammalian Cell His
    Zebrafish EIF2S3-11986Z Recombinant Zebrafish EIF2S3 Mammalian Cell His

    EIF2S3 involved in several pathways and played different roles in them. We selected most pathways EIF2S3 participated on our site, such as ABC-family proteins mediated transport, Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, Cap-dependent Translation Initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF2S3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ABC-family proteins mediated transport ABCF1; ABCA4A; ABCB8; APOA1B; ABCA8; ABCC2; ABCE1; ABCC9; KCNJ11; ABCG4B
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S EIF4E; EIF4A1; EIF4EBP1; EIF2S3; EIF2S1A; EIF3K; EIF4H; FAUB; EIF1AX; EIF4B
    Cap-dependent Translation Initiation EIF2B1; EIF1AX; FAUB; EIF4A1; EIF2S1A; EIF4H; EIF2S3; EIF5; EIF4E; EIF4EB
    Eukaryotic Translation Initiation EIF4B; EIF2B1; EIF2S1A; EIF5; EIF4A2; EIF4G1; EIF4A1; RPL35; EIF4EB; EIF4H
    Formation of the ternary complex, and subsequently, the 43S complex EIF2S1A; EIF2S1; EIF1AXA; EIF2S3; EIF1AX; EIF3K; FAUB
    GTP hydrolysis and joining of the 60S ribosomal subunit EIF1AXA; EIF4A1; EIF2S1A; EIF3K; EIF2S3; FAUB; EIF2S1; EIF4H; EIF5; EIF4A2
    Gene Expression IGF2BP3; CSTF2; ZNF785; ZNF471; LAMTOR1; GATAD2AB; ZNF354B; ZNF596; NR4A2B; METTL3
    L13a-mediated translational silencing of Ceruloplasmin expression EIF3K; EIF2S3; FAUB; EIF1AXA; EIF4H; EIF2S1A; EIF1AX

    EIF2S3 has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF2S3 itself. We selected most functions EIF2S3 had, and list some proteins which have the same functions with EIF2S3. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activity RAB6B; RAB34A; EEF1A1A; RAB9A; RAB1BA; EIF5; RHOA; RHEB; EEF2B; GNB5
    protein binding PXMP2; PTPN18; CD69; BID; RCOR1; POMP; ZNF114; GSE1; TICAM2; COA5
    translation factor activity, RNA binding GTF2H2; EEF2K; EIF1AX; EIF1; MTIF3; SOX11; EEF1A2; PPP1R2P9; CPEB3; EIF4G1
    translation initiation factor activity GTPBP1L; EIF5B; EIF2S2; EIF4A1; AGO2; EIF3B; EIF3J; EIF1AY; EIF1AXA; GTPBP1

    EIF2S3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF2S3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF2S3.

    EIF2S1; EIF2S2; EIF1B; GH1; HLA-B; CASP4; IKBKE; NDRG1; PRKAB1; TRAF6; yopM; ychF; ssrna_ug

    Chang, YT; Yao, CT; et al. Verification of gene expression profiles for colorectal cancer using 12 internet public microarray datasets. WORLD JOURNAL OF GASTROENTEROLOGY 20:17476-17482(2014).
    Chang, YT; Huang, CS; et al. Gene expression profile of peripheral blood in colorectal cancer. WORLD JOURNAL OF GASTROENTEROLOGY 20:14463-14471(2014).

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