EIF2A

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EIF2A

Official Full Name eukaryotic translation initiation factor 2A, 65kDa
Background EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al.,;2002 (PubMed 12133843)).
Synonyms EIF2A; eukaryotic translation initiation factor 2A, 65kDa; eukaryotic translation initiation factor 2A; EIF 2A; 65 kDa eukaryotic translation initiation factor 2A; CDA02; EIF-2A; MST089; MSTP004; MSTP089
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EIF2A-12348H Recombinant Human EIF2A, GST-tagged E.coli GST
    Human EIF2A-18H Recombinant Human EIF2A protein, His-tagged E.coli His
    Human EIF2A-28490TH Recombinant Human EIF2A, His-tagged E.coli His
    Human EIF2A-30H Recombinant Human EIF2A Sf9 Insect Cell N/A
    Human EIF2A-3145H Recombinant Human EIF2A Protein, GST-tagged Wheat Germ GST
    Human EIF2A-338H Recombinant Human EIF2A Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human EIF2A-6675HCL Recombinant Human EIF2A 293 Cell Lysate HEK293 N/A
    Mouse Eif2a-2770M Recombinant Mouse Eif2a Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse EIF2A-5074M Recombinant Mouse EIF2A Protein Mammalian Cell His
    Chicken EIF2A-2977C Recombinant Chicken EIF2A Mammalian Cell His
    Zebrafish EIF2A-3075Z Recombinant Zebrafish EIF2A Mammalian Cell His

    EIF2A involved in several pathways and played different roles in them. We selected most pathways EIF2A participated on our site, such as IL-6 Signaling Pathway, TGF-beta receptor signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    IL-6 Signaling Pathway DAXX; BMX; CDK5R1B; EIF2A
    TGF-beta receptor signaling EIF2A; STRAP; TGFBR3; DAB2

    EIF2A has several biochemical functions, for example, protein binding, ribosome binding, tRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF2A itself. We selected most functions EIF2A had, and list some proteins which have the same functions with EIF2A. You can find most of the proteins on our site.

    Function Related Protein
    protein binding RHOBTB3; MED8; TAE1; CD2BP2; KDM2B; ENTPD1; GTF3C3; CCDC22; KDM6B; VDR
    ribosome binding CPEB2; SEC61A1; EIF2S1; IGHMBP2; ERI1; CPEB1; BAG6; ETF1A; WIBG; YTHDF1
    tRNA binding EIF2AK4; RPL35A; TERT; EIF2A; TRMT11; CARS; MARS; TRNT1; PTCD1; AIMP1
    translation initiation factor activity EIF3JA; EIF4A2; GTPBP1; EIF4A1; GTPBP1L; EIF4EB; EIF3J; AGO2; EIF3JB; EIF3BA

    EIF2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF2A here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF2A.

    MLH1; q81z87_bacan; MAST3; ABL1; NEDD8; ESR2; UPF1

    Dametto, P; Lakkaraju, AKK; et al. Neurodegeneration and Unfolded-Protein Response in Mice Expressing a Membrane-Tethered Flexible Tail of PrP. PLOS ONE 10:-(2015).
    Wu, CX; Wang, SJ; et al. The Z alpha domain of PKZ from Carassius auratus can bind to d(GC)(n) in negative supercoils. FISH & SHELLFISH IMMUNOLOGY 28:783-788(2010).

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