EIF5A

  • Official Full Name

    eukaryotic translation initiation factor 5A

  • Overview

    Eukaryotic translation initiation factor 5A-1 is a protein that in humans is encoded by the EIF5A gene.
  • Synonyms

    EIF5A; eukaryotic translation initiation factor 5A; eukaryotic translation initiation factor 5A-1; EIF 5A; EIF5A1; MGC99547; MGC104255; eIF 4D; eIF 5A 1; eIF 5A1; eIF-4D; eIF-5A; eIF-5A-1; eIF-5A1; eIF4D; eIF5AI; Eukaryotic initiation factor 5A; Eukaryotic initiation factor 5A isoform 1; Eukaryotic translation initiation factor 5A 1; IF5A1_HUMAN; Rev binding factor; Rev-binding factor; uORF A; uORF;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Strep
  • Myc
  • DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EIF5A-362H Recombinant Human Eukaryotic Translation Initiation Factor 5A E.coli N/A
Human EIF5A-28549TH Recombinant Human EIF5A E.coli N/A
Human EIF5A-12388H Recombinant Human EIF5A, GST-tagged E.coli GST 1-154a.a.
Human EIF5A-27179TH Recombinant Human EIF5A, His-tagged E.coli His
Human EIF5A-3213H Recombinant Human EIF5A Protein, GST-tagged Wheat Germ GST
Human EIF5A-273H Recombinant Human EIF5A protein(Met1-Lys154), His-tagged E.coli N-His Met1-Lys154
Human EIF5A-6641HCL Recombinant Human EIF5A 293 Cell Lysate HEK293 N/A
Human EIF5A-1946HFL Recombinant Full Length Human EIF5A Protein, C-Flag-tagged Mammalian cells Flag
Human EIF5A-4870H Recombinant Human EIF5A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EIF5A-2862H Recombinant Human EIF5A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EIF5A-6427H Recombinant Human EIF5A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EIF5A-0709H Recombinant Human EIF5A Protein (M1-K154), Tag Free E.coli No tag M1-K154
Human EIF5A-4299HF Recombinant Full Length Human EIF5A Protein, GST-tagged In Vitro Cell Free System GST 154 amino acids
Human EIF5A-831H Recombinant Human EIF5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human EIF5A-831H-B Recombinant Human EIF5A Protein Pre-coupled Magnetic Beads HEK293
Human EIF5A-0710H Recombinant Human EIF5A Protein (M1-K154), His/Strep tagged E.coli His/Strep M1-K154
Mouse EIF5A-5117M Recombinant Mouse EIF5A Protein Mammalian Cell His
Mouse Eif5a-2792M Recombinant Mouse Eif5a Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse EIF5A-2726M-B Recombinant Mouse EIF5A Protein Pre-coupled Magnetic Beads HEK293
Mouse EIF5A-2726M Recombinant Mouse EIF5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat EIF5A-2070R Recombinant Rat EIF5A Protein Mammalian Cell His
Rat EIF5A-1727R Recombinant Rat EIF5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat EIF5A-1727R-B Recombinant Rat EIF5A Protein Pre-coupled Magnetic Beads HEK293
Zebrafish EIF5A-12397Z Recombinant Zebrafish EIF5A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

EIF5A involved in several pathways and played different roles in them. We selected most pathways EIF5A participated on our site, such as Gamma carboxylation, hypusine formation and arylsulfatase activation, Hypusine synthesis from eIF5A-lysine, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gamma carboxylation, hypusine formation and arylsulfatase activationOTOP2;ARSI;DOHH;DPH5;EEF2;ARSJ;FURINA;ARSE;GAS6
Hypusine synthesis from eIF5A-lysineDHPS;EIF5A2;DOHH;EIF5A
Metabolism of proteinsADAMTS1;ADAMTSL3;SEC63;IGFBP5B;SPON1B;SEC22C;ST3GAL3A;MUC4;EEF1A2
Post-translational protein modificationLMAN2L;NAPB;YKT6;DPH5;ALG14;MIA3;SMC5;ARSH;MUCL1
Translation FactorsEEF1B2;EIF2B1;PAIP1;EEF1D;EIF5A;EEF2B;EEF1G;EIF4EBP2;EEF1A2

EIF5A has several biochemical functions, for example, RNA binding, U6 snRNA binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF5A itself. We selected most functions EIF5A had, and list some proteins which have the same functions with EIF5A. You can find most of the proteins on our site.

Function Related Protein
RNA bindingTERT;HNRNPUL1;D19BWG1357E;SUZ12;PKZ;SRSF10;RBMS1;HNRNPK;RBM48
U6 snRNA bindingSART3;LSM4;LSM8;LSM7;DDX39B;PRPF8;LSM2;RBM22;EIF5A
poly(A) RNA bindingKPNB1;PPAN;SAMD4A;APOBEC3C;MACF1;MEPCE;TNRC6B;ZNF326;EIF3H
protein N-terminus bindingID1;SCT;UNC13A;SYNGR3;PPP1CC;ERCC6;RPA2;KCNQ2;PEX5
protein bindingGRIP1;ARAP3;NKD1;ZGPAT;KDM2B;BCS1L;DGCR8;TIPRL;ACVR2B
ribosome bindingEIF6;ERI1;SBDS;EIF5A2;EIF2S1;EIF5A;EFTUD1;RICTOR;ETF1A
translation elongation factor activityEEF1G;EEFSEC;EEF1A1A;EIF5A2;EFTUD1;EEF1D;HBS1L;EEF1A1L1;EEF1B2

EIF5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF5A here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF5A.

MEOX2; CRX; DHPS; REL; KAT2B; Pds5a; Csnk1e; gerLA; XRN2; GABARAP; SOD1; NS

Research Area

Related articles

Carvajal-Gamez, BI; Quintas-Granados, LI; et al. Translation initiation factor eIF-5A; the hypusine-containing protein, is phosphorylated on serine and tyrosine and O-glycosylated in Trichomonas vaginalis. MICROBIAL PATHOGENESIS 52:177-183(2012).
Kim, YS; Lee, SS; et al. Immunohistochemical Array for Clear Cell Type Mucoepidermoid Carcinoma. KOREAN JOURNAL OF PATHOLOGY 44:284-294(2010).
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