EIF5A
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Official Full Name
eukaryotic translation initiation factor 5A
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Overview
Eukaryotic translation initiation factor 5A-1 is a protein that in humans is encoded by the EIF5A gene. -
Synonyms
EIF5A; eukaryotic translation initiation factor 5A; eukaryotic translation initiation factor 5A-1; EIF 5A; EIF5A1; MGC99547; MGC104255; eIF 4D; eIF 5A 1; eIF 5A1; eIF-4D; eIF-5A; eIF-5A-1; eIF-5A1; eIF4D; eIF5AI; Eukaryotic initiation factor 5A; Eukaryotic initiation factor 5A isoform 1; Eukaryotic translation initiation factor 5A 1; IF5A1_HUMAN; Rev binding factor; Rev-binding factor; uORF A; uORF;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- Fc
- Avi
- Strep
- Myc
- DDK
- N
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
EIF5A involved in several pathways and played different roles in them. We selected most pathways EIF5A participated on our site, such as Gamma carboxylation, hypusine formation and arylsulfatase activation, Hypusine synthesis from eIF5A-lysine, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gamma carboxylation, hypusine formation and arylsulfatase activation | ARSK;SUMF2;DPH1;PROCA;OTOP2;DPH2;ARSH;EIF5A2;DPH3 |
| Hypusine synthesis from eIF5A-lysine | DOHH;EIF5A;DHPS;EIF5A2 |
| Metabolism of proteins | DDIT3;BCS1L;NANP;STT3A;MTX2;SLC38A8;SPON1;EIF5A2;ADAMTSL1 |
| Post-translational protein modification | MCFD2;ST6GALNAC1.2;MPDU1A;TMED10;MGAT4B;GCNT3;GNE;MAGT1;TRAPPC9 |
| Translation Factors | EEF1G;EIF4EBP2;EIF5A;EEF2B;EIF2B1;EEF1A2;PAIP1;EIF1;EEF1B2 |
EIF5A has several biochemical functions, for example, RNA binding, U6 snRNA binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF5A itself. We selected most functions EIF5A had, and list some proteins which have the same functions with EIF5A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | TERT;PRPF6;ASCC1;EXOSC5;PUF60B;RAD51AP1;RPL27A;DZIP3;PATL1 |
| U6 snRNA binding | LSM7;PRPF8;DDX39B;RBM22;LSM2;SART3;LSM8;PRPF4;LSM4 |
| poly(A) RNA binding | TRA2A;RPS18;HIST1H4F;NAP1L4;TWF2;PABPN1;RPS26;ZFP768;CCDC86 |
| protein N-terminus binding | TDRD7;THAP7;MEN1;SCT;SNF8;KCNQ2;SUV39H1;PHB2;STX1A |
| protein binding | PELI3;DEF6;BLOC1S1;FZD8;DDO;PTPN23;PDCD6IP;CSPG5;CLIP4 |
| ribosome binding | CPEB1A;WIBG;CPEB3;ETF1B;CPEB4;C12orf65;NAA16;RPSA;PPP1R2P9 |
| translation elongation factor activity | EEF1A1B;TSFM;EEF2A.1;EEF1E1;EEF1DB;EEF1D;EIF5A;EEF2A.2;ABTB1 |
EIF5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF5A here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF5A.
MEOX2; CRX; DHPS; REL; KAT2B; Pds5a; Csnk1e; gerLA; XRN2; GABARAP; SOD1; NS
Research Area
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