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Official Full Name eukaryotic translation initiation factor 2C, 3
Background This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded;protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in;short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely;related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript;variants encoding distinct isoforms have been identified for this gene.
Synonyms EIF2C3; eukaryotic translation initiation factor 2C, 3; protein argonaute-3; 5730550L01Rik; Ago 3; Ago3; AGO3_HUMAN; Argonaute3; eIF 2C 3; eIF-2C 3; eIF2C 3; EIF2C3 protein; Eukaryotic translation initiation factor 2C 3; Eukaryotic translation initiation factor 2C3; FLJ12765; hAgo3; MGC86946; mAgo3; argonaute 3; Piwi/Argonaute family protein meIF2C3; AW048688; C130014L07Rik
    • Species :
    • Human
    • Mouse
    • Source :
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EIF2C3-3166H Recombinant Human EIF2C3 Protein, GST-tagged Wheat Germ GST
    Human EIF2C3-5174H Recombinant Human EIF2C3, His tagged Insect Cell His
    Human EIF2C3-6666HCL Recombinant Human EIF2C3 293 Cell Lysate HEK293 N/A
    Mouse EIF2C3-5085M Recombinant Mouse EIF2C3 Protein Mammalian Cell His

    eif2c3 involved in several pathways and played different roles in them. We selected most pathways eif2c3 participated on our site, such as Gene Expression, Gene Silencing by RNA, Post-transcriptional silencing by small RNAs, which may be useful for your reference. Also, other proteins which involved in the same pathway with eif2c3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gene Expression SEC61B; KHSRP; LAMTOR1; PPARAA; ZMAT5; ZNF213; TRMT112; ZNF689; ZNF547; SAP30BP
    Gene Silencing by RNA TNRC6B; TSN; TSNAX; AGO3B; MYBL1; DDX4; MAEL; DPY19L2; TDRD1; HENMT1
    Post-transcriptional silencing by small RNAs TNRC6B; EIF2C3; AGO3B

    eif2c3 has several biochemical functions, for example, RNA binding, double-stranded RNA binding, miRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by eif2c3 itself. We selected most functions eif2c3 had, and list some proteins which have the same functions with eif2c3. You can find most of the proteins on our site.

    Function Related Protein
    double-stranded RNA binding OASL; OAS3; MBNL1; TLR3; OASL1; ILF3; DICER1; PRKRIP1; CLTC; ADARB1
    miRNA binding AGO3; TARBP2; DICER1; AGO1; MEF2C; LIN28A; EIF2C3; PNPT1; AGO4; SOX2
    nucleic acid binding NARS2; ZBTB18; ZFP184; YY1B; ZSCAN4F; ZFPM2; HNRPL; ZFP426; RAVER1; NYNRIN
    poly(A) RNA binding AKAP8; KIAA1967; EIF3A; TRIM56; ETF1A; DYNC1LI1; RPL5; CSNK1E; NKAP; IFIT2
    single-stranded RNA binding STRBP; DDX58; HMGB1; HNRNPA1; PIWIL1; ZFP36; ANXA1; DLX2; HNRNPF; TLR8

    eif2c3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with eif2c3 here. Most of them are supplied by our site. Hope this information will be useful for your research of eif2c3.


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