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Official Full Name eukaryotic translation initiation factor 3, subunit K
Background The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits,;including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and;promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 (PubMed 14519125)).
Synonyms EIF3K; eukaryotic translation initiation factor 3, subunit K; EIF3S12, eukaryotic translation initiation factor 3, subunit 12; eukaryotic translation initiation factor 3 subunit K; ARG134; HSPC029; M9; PLAC 24; PRO1474; PTD001; eIF-3 p25; eIF-3 p2
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EIF3K-001HCL Recombinant Human EIF3K cell lysate Insect Cell N/A
    Human EIF3K-27408TH Recombinant Human EIF3K, His-tagged E.coli His
    Human EIF3K-3191H Recombinant Human EIF3K Protein, GST-tagged Wheat Germ GST
    Human EIF3K-3482H Recombinant Human EIF3K, His-tagged E.coli His
    Human EIF3K-5518H Recombinant Human EIF3K Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human EIF3K-8658H Recombinant Human EIF3K, His-GST tagged Insect Cell His
    Mouse Eif3k-2782M Recombinant Mouse Eif3k Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse EIF3K-5100M Recombinant Mouse EIF3K Protein Mammalian Cell His
    Rhesus Macaque EIF3K-1425R Recombinant Rhesus monkey EIF3K Protein, His-tagged Mammalian Cell His
    Zebrafish EIF3K-2361Z Recombinant Zebrafish EIF3K Mammalian Cell His
    CBCRY12 Eukaryotic translation initiation factor 3 subunit K E.coli N/A

    eif3k involved in several pathways and played different roles in them. We selected most pathways eif3k participated on our site, such as Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, Cap-dependent Translation Initiation, Eukaryotic Translation Initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with eif3k were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S EIF4G1; EIF4EBP1; EIF4H; FAUB; EIF4A1; EIF4E; EIF4EB; EIF3K; EIF1AX; EIF2S1
    Cap-dependent Translation Initiation EIF5; EIF1AXA; EIF2S1A; EIF4A2; FAUB; EIF3K; EIF2B1; EIF4B; EIF2S1; EIF1AX
    Eukaryotic Translation Initiation EIF4A1; EIF1AX; EIF2S1A; EIF4EB; EIF4B; RPL35; FAUB; EIF4A2; EIF5; EIF2B1
    Formation of a pool of free 40S subunits FAUB; EIF3K; EIF1AX; RPL35; EIF1AXA
    Formation of the ternary complex, and subsequently, the 43S complex EIF2S3; EIF2S1; FAUB; EIF2S1A; EIF1AX; EIF3K; EIF1AXA
    GTP hydrolysis and joining of the 60S ribosomal subunit RPL35; EIF3K; EIF2S1A; EIF4H; EIF1AX; EIF5; EIF4B; FAUB; EIF4A1; EIF1AXA
    Gene Expression POP7; ZNF692; ESR2B; ZNF621; C7orf59; ZNF471; COX5B; WDR4; BRF1B; PRDM7
    L13a-mediated translational silencing of Ceruloplasmin expression FAUB; EIF4H; EIF1AX; EIF2S3; EIF2S1A; EIF3K; EIF1AXA

    eif3k has several biochemical functions, for example, RNA binding, ribosome binding, contributes_to translation initiation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by eif3k itself. We selected most functions eif3k had, and list some proteins which have the same functions with eif3k. You can find most of the proteins on our site.

    Function Related Protein
    RNA binding RPL21; SUZ12; PPP5C; DHX34; PDCD4; CPSF3; AKAP1; RNASEL4; Akap17b; C14orf166
    ribosome binding WIBG; MTRF1; IGHMBP2; NARG1; ERI1; BAG6; EIF5A; MTRF1L; SEC61A1; CPEB1B
    contributes_to translation initiation factor activity EIF2B1; EIF3C; EIF3F; EIF3BA; EIF2B2; EIF2B5; EIF3H; EIF3E; EIF3S10; EIF3G

    eif3k has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with eif3k here. Most of them are supplied by our site. Hope this information will be useful for your research of eif3k.

    Eif3a; Ywhae

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