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Official Full Name eukaryotic translation initiation factor 3, subunit A
Background Eukaryotic translation initiation factor 3 subunit A is a protein that in humans is encoded by the EIF3A gene. EIF3A has been shown to interact with EIF3EIP, EIF4B, DISC1, FBXO32, EIF3D, EIF3C, EIF4G2, EIF3B, EIF3J, EIF3S6, EIF3F, EIF3G, EIF3H, EIF3I and EIF3K.
Synonyms eif3a; eukaryotic translation initiation factor 3, subunit A; ncl; eif3; tif32; eif3s10; Nucleolin; eIF3-p170; eif3-theta; nucleolin; Eukaryotic translation initiation factor 3 subunit 10; oocyte nuclear protein
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EIF3A-3177H Recombinant Human EIF3A Protein, GST-tagged Wheat Germ GST
    Human EIF3A-6664HCL Recombinant Human EIF3A 293 Cell Lysate HEK293 N/A
    Mouse Eif3a-1929M Recombinant Mouse Eif3a protein, His & T7-tagged E.coli His/T7
    Mouse EIF3A-5091M Recombinant Mouse EIF3A Protein Mammalian Cell His
    Rat EIF3A-2055R Recombinant Rat EIF3A Protein Mammalian Cell His

    eif3a involved in several pathways and played different roles in them. We selected most pathways eif3a participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with eif3a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA transport NUP160; SNUPN; EIF3B; SMN; TPR; PAIP1; RPP38; KPNB1; EIF4A1A; EIF3S10

    eif3a has several biochemical functions, for example, poly(A) RNA binding, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by eif3a itself. We selected most functions eif3a had, and list some proteins which have the same functions with eif3a. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding TES; RBM12; NIP7; SRP19; S100A4; MECP2; YTHDC1; DUSP11; EXOSC9; HRSP12
    protein binding TPRGL; REEP6; PDIA3; GK; RPS7; KRTAP3-3; AIG1; TNNI3; MYL6B; PIGK
    structural molecule activity CAV1; CLDNI; INAA; KRT95; CLDN5B; CLTB; CLDN17; NUMA1; CLDN10B; SEMG1
    contributes_to translation initiation factor activity EIF3F; EIF2B2; EIF3D; EIF3M; EIF3E; EIF3A; EIF3EB; EIF3I; EIF3HA; EIF2B5

    eif3a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with eif3a here. Most of them are supplied by our site. Hope this information will be useful for your research of eif3a.


    Yin, JY; Meng, XG; et al. Association of positively selected eIF3a polymorphisms with toxicity of platinum-based chemotherapy in NSCLC patients. ACTA PHARMACOLOGICA SINICA 36:375-384(2015).
    Aylett, CHS; Boehringer, D; et al. Structure of a Yeast 40S-eIF1-eIF1A-eIF3-eIF3j initiation complex. NATURE STRUCTURAL & MOLECULAR BIOLOGY 22:269-271(2015).

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