Recombinant Human CA3 Protein (M1-K260), His/Strep tagged

• Cat.No.: CA3-1051H
• Product Overview: Recombinant Human 6His-strepII-TEV-GG-CA3(M1-K260 end) Protein was expressed in E. coli.

Specification

• Description: Reversible hydration of carbon dioxide.
• Source: E. coli
• Species: Human
• Tag: His&Strep
• Form: Liquid
• Protein Length: M1-K260
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: CA3 carbonic anhydrase III, muscle specific [ Homo sapiens (human) ]
• Official Symbol: CA3
• Synonyms: CA3; carbonic anhydrase III, muscle specific; carbonic anhydrase 3; CAIII; Car3; CA-III; carbonate dehydratase III; FLJ36434
• Gene ID: 761
• mRNA Refseq: NM_005181
• Protein Refseq: NP_005172
• MIM: 114750
• UniProt ID: P07451

Reviews

09/23/2022

Outstanding protein sequencing capabilities, unrivaled accuracy.

05/23/2022

Precise purification techniques, yield exceptional samples.

05/25/2021

Efficient sample handling, optimizes our laboratory workflow.

Q&As

In which tissues is CA3 expression most prominently observed?

CA3 is primarily found in skeletal muscles.

What post-translational modifications are characteristic of CA3?

Post-translational modifications, like phosphorylation or glycosylation, can be identified using mass spectrometry.

Are there known inhibitors that specifically target CA3?

Specific inhibitors for CA3 are yet to be fully elucidated and would be determined using enzymatic assays.

How does CA3 participate in metabolic processes within the cell?

CA3 plays a role in CO2 and bicarbonate equilibrium, crucial for metabolic pathways like glycolysis and the citric acid cycle.

How does CA3 enzymatic activity differ from other carbonic anhydrase isoforms?

While CA3 has a similar mechanism, its activity and affinity might differ from other isoforms, requiring comparative studies.

Are there any pathological conditions directly linked to CA3 dysregulation?

CA3 dysregulation might be linked to muscle diseases or metabolic disorders, requiring further research.

What is the primary physiological role of CA3 in cells?

CA3 catalyzes the reversible hydration of carbon dioxide, aiding in pH regulation and CO2 transport.