CA6

  • Official Full Name

    carbonic anhydrase VI

  • Overview

    The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown.
  • Synonyms

    CA6; carbonic anhydrase VI; carbonic anhydrase 6; CA VI; CA-VI; CAH6_HUMAN; Carbonate dehydratase VI; carbonic anhydrase VI nirs variant 1; carbonic anhydrase VI nirs variant 3; GUSTIN; MGC21256; Salivary carbonic anhydrase; Secreted carbonic anhydrase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Human milk
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • MYC
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CA6-527H Active Recombinant Human CA6, His-tagged Mammalian cells His
Human CA6-26132TH Recombinant Human CA6 Wheat Germ N/A 308 amino acids
Human CA6-0245H Recombinant Human CA6 Protein, GST-Tagged Wheat Germ GST
Human CA6-26443TH Recombinant Human CA6 Wheat Germ N/A 100 amino acids
Human CA6-266HCL Recombinant Human CA6 cell lysate N/A
Human CA6-2268H Recombinant Human CA6 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CA6-2742HF Recombinant Full Length Human CA6 Protein, GST-tagged In Vitro Cell Free System GST 308 amino acids
Human CA6-350H Recombinant Human CA6 Protein, His&GST-tagged E.coli N-His&GST Gln18-Asn308
Human CA6-804H Native Human CA6 Human milk N/A
Human CA6-2577H Recombinant Human CA6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CA6-45HF Recombinant Full Length Human CA6 Protein In Vitro Cell Free System 308 amino acids
Human CA6-2577H-B Recombinant Human CA6 Protein Pre-coupled Magnetic Beads HEK293
Mouse CAR6-2723M Recombinant Mouse CAR6 Protein Mammalian Cell His
Mouse Car6-7840M Recombinant Mouse Car6 protein, His-tagged E.coli His Thr194~Phe313 (Accession # P18761)
Mouse Car6-7839M Recombinant Mouse Car6 protein, His-tagged E.coli His Asp27~Ser181 (Accession # P18761)
Mouse CA6-1161M Recombinant Mouse CA6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Car6-826M Recombinant Mouse Car6 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse CA6-1161M-B Recombinant Mouse CA6 Protein Pre-coupled Magnetic Beads HEK293
Rat Car6-7841R Recombinant Rat Car6 protein, His & T7-tagged E.coli His/T7 Thr147~Ala275 (Accession # F1LQ08)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CA6 involved in several pathways and played different roles in them. We selected most pathways CA6 participated on our site, such as Nitrogen metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Nitrogen metabolismCA4A;CAR15;GLULA;CA6;GLULC;CAR13;CA4B;Car12;CA9

CA6 has several biochemical functions, for example, carbonate dehydratase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CA6 itself. We selected most functions CA6 had, and list some proteins which have the same functions with CA6. You can find most of the proteins on our site.

Function Related Protein
carbonate dehydratase activityCA13;CA4;CA15B;CAR1;CA2;CA12;Car8;Car14;Car4
zinc ion bindingRNF24;ESR2B;PHC2;VPS11;TCEA3;DTNA;ZFP622;RBCK1;LNX2A

CA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CA6.

Research Area

Related articles

Shen, L; Suresh, L; et al. Novel autoantibodies in Sjogren's syndrome. CLINICAL IMMUNOLOGY 145:251-255(2012).
Okudaira, T; Hirashima, M; et al. A modified version of galectin-9 suppresses cell growth and induces apoptosis of human T-cell leukemia virus type I-infected T-cell lines (Retracted article. See vol. 129, pg. 2762, 2011). INTERNATIONAL JOURNAL OF CANCER 120:2251-2261(2007).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
Are there known genetic mutations in the CA6 gene, and how do they influence protein function? 04/05/2021

Genetic variations might affect CA6's secretion or activity, necessitating functional assays for evaluation.

What is the primary physiological function of CA6? 02/04/2021

CA6 plays a role in the reversible conversion of CO2 to bicarbonate and protons, aiding in pH balance and CO2 transport.

Are there any known proteins or molecules that interact directly with CA6? 05/27/2020

Direct interaction partners for CA6 require further investigation, but it may have specific binding properties due to its unique location.

Where is CA6 predominantly located within the human body? 04/09/2020

CA6 is mainly secreted in saliva and is found in salivary glands.

What are the post-translational modifications identified on CA6? 12/21/2019

Specific post-translational modifications on CA6 can be explored through techniques like mass spectrometry.

How does the enzymatic activity of CA6 compare to other carbonic anhydrase isoforms? 03/31/2018

CA6's activity might be tailored for salivary pH regulation, potentially differing in kinetics from other isoforms.

Are there specific pathological conditions linked with CA6 dysregulation? 06/24/2017

Dysregulation of CA6 might influence oral health, pH regulation, or conditions affecting the salivary glands.

Customer Reviews (3)

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Reviews
12/15/2021

    Outstanding purification techniques, yield top-notch samples.

    09/26/2021

      Fast turnaround time, meets our project deadlines efficiently.

      07/01/2021

        Efficient sample handling, simplifies our daily workloads.

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