CA6
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Official Full Name
carbonic anhydrase VI
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Overview
The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown. -
Synonyms
CA6; carbonic anhydrase VI; carbonic anhydrase 6; CA VI; CA-VI; CAH6_HUMAN; Carbonate dehydratase VI; carbonic anhydrase VI nirs variant 1; carbonic anhydrase VI nirs variant 3; GUSTIN; MGC21256; Salivary carbonic anhydrase; Secreted carbonic anhydrase;
- Recombinant Proteins
- Cell & Tissue Lysates
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- Human milk
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- GST
- His
- Fc
- Avi
- Myc
- T7
- DDK
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CA6-527H | Active Recombinant Human CA6, His-tagged | Mammalian cells | His | Gln18-Asn308 |
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| Human | CA6-26132TH | Recombinant Human CA6 | Wheat Germ | Non | 308 amino acids |
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| Human | CA6-0245H | Recombinant Human CA6 Protein, GST-Tagged | Wheat Germ | GST |
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| Human | CA6-26443TH | Recombinant Human CA6 | Wheat Germ | Non | 100 amino acids |
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| Human | CA6-266HCL | Recombinant Human CA6 cell lysate | Non |
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| Human | CA6-2268H | Recombinant Human CA6 Protein, MYC/DDK-tagged | HEK293 | Myc&DDK |
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| Human | CA6-2742HF | Recombinant Full Length Human CA6 Protein, GST-tagged | In Vitro Cell Free System | GST | 308 amino acids |
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| Human | CA6-350H | Recombinant Human CA6 Protein, His&GST-tagged | E.coli | His&GST | Gln18-Asn308 |
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| Human | CA6-804H | Native Human CA6 | Human milk | Non |
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| Human | CA6-613H | Recombinant Human CA6 protein, His&Myc-tagged | E.coli | His&Myc | 18-308a.a. |
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| Human | CA6-2577H | Recombinant Human CA6 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Human | CA6-45HF | Recombinant Full Length Human CA6 Protein | In Vitro Cell Free System | 308 amino acids |
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| Human | CA6-2577H-B | Recombinant Human CA6 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | CAR6-2723M | Recombinant Mouse CAR6 Protein | Mammalian Cell | His |
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| Mouse | Car6-7840M | Recombinant Mouse Car6 protein, His-tagged | E.coli | His | Thr194~Phe313 |
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| Mouse | Car6-7839M | Recombinant Mouse Car6 protein, His-tagged | E.coli | His | Asp27~Ser181 |
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| Mouse | CA6-1161M | Recombinant Mouse CA6 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Mouse | Car6-826M | Recombinant Mouse Car6 Protein, MYC/DDK-tagged | HEK293T | Myc&DDK |
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| Mouse | CA6-1161M-B | Recombinant Mouse CA6 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | Car6-7841R | Recombinant Rat Car6 protein, His & T7-tagged | E.coli | His&T7 | Thr147~Ala275 |
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- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
CA6 involved in several pathways and played different roles in them. We selected most pathways CA6 participated on our site, such as Nitrogen metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Nitrogen metabolism | CAR13;GLUD2;CA6;GLUD1B;CA2;GLULA;Car8;CAR7;Car12 |
CA6 has several biochemical functions, for example, carbonate dehydratase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CA6 itself. We selected most functions CA6 had, and list some proteins which have the same functions with CA6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbonate dehydratase activity | CA15A;Car14;CA7;CA4A;CA2;Car9;CA14;CA8;CA13 |
| zinc ion binding | RBM4.2;CXXC1B;LMO7B;ADAMTS7;MAP3K7IP3;BIRC3;NR2F5;ZMIZ2;APEX2 |
CA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CA6.
Research Area
Related articles
- Reviews
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Q&As (7)
Ask a questionGenetic variations might affect CA6's secretion or activity, necessitating functional assays for evaluation.
CA6 plays a role in the reversible conversion of CO2 to bicarbonate and protons, aiding in pH balance and CO2 transport.
Direct interaction partners for CA6 require further investigation, but it may have specific binding properties due to its unique location.
CA6 is mainly secreted in saliva and is found in salivary glands.
Specific post-translational modifications on CA6 can be explored through techniques like mass spectrometry.
CA6's activity might be tailored for salivary pH regulation, potentially differing in kinetics from other isoforms.
Dysregulation of CA6 might influence oral health, pH regulation, or conditions affecting the salivary glands.
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