• Official Full Name

    carbonic anhydrase VII

  • Overview

    Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the salivary glands. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms.
  • Synonyms

    CA7; carbonic anhydrase VII; carbonic anhydrase 7; CA 7; CA VII; CA-VII; CAH7_HUMAN; Car7; Carbonate dehydratase VII; Carbonic dehydratase; CAVII; OTTHUMP00000174821; OTTHUMP00000242940; carbonic dehydratase VII;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Strep
  • Myc
  • DDK
  • MYC
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CA7-557H Active Recombinant Human CA7 Protein, His-tagged E.coli His Thr2-Ala264
Human CA7-51H Recombinant Human CA7 E.coli N/A
Human CA7-707H Recombinant Human CA7 E.coli N/A
Human CA7-0247H Recombinant Human CA7 Protein, GST-Tagged Wheat Germ GST
Human CA7-2499H Active Recombinant Human CA7 protein(Met1-Ala264), His-tagged E.coli C-His Met1-Ala264
Human CA7-7913HCL Recombinant Human CA7 293 Cell Lysate HEK293 N/A
Human CA7-2743HF Recombinant Full Length Human CA7 Protein, GST-tagged In Vitro Cell Free System GST 264 amino acids
Human CA7-1052H Recombinant Human CA7 Protein (M1-A264), Tag Free E.coli No tag M1-A264
Human CA7-1284H Recombinant Human CA7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CA7-1053H Recombinant Human CA7 Protein (M1-A264), His/Strep tagged E.coli His/Strep M1-A264
Mouse Car7-7842M Recombinant Mouse Car7 protein, His-tagged E.coli His Ser58~Pro217 (Accession # Q9ERQ8)
Mouse CAR7-2724M Recombinant Mouse CAR7 Protein Mammalian Cell His
Mouse CA7-1162M-B Recombinant Mouse CA7 Protein Pre-coupled Magnetic Beads HEK293
Mouse Car7-769M Recombinant Mouse Car7 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse CA7-1162M Recombinant Mouse CA7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Car7-7843R Recombinant Rat Car7 protein, His-tagged E.coli His Arg29~Asp173 (Accession # B2RZ61)
Zebrafish CA7-11069Z Recombinant Zebrafish CA7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CA7 involved in several pathways and played different roles in them. We selected most pathways CA7 participated on our site, such as Nitrogen metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CA7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Nitrogen metabolismCar12;GLULB;CAR5A;CA5;GLUL;CA7;Car8;CAR6;Car9

CA7 has several biochemical functions, for example, carbonate dehydratase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CA7 itself. We selected most functions CA7 had, and list some proteins which have the same functions with CA7. You can find most of the proteins on our site.

Function Related Protein
carbonate dehydratase activityCA15B;CAR5A;Car12;CA4;CAR15;CA2;CA4A;Car14;CAR3
zinc ion bindingTRIM35-39;FTR72;MORC2A;L3MBTL4;LIN28B;RORCB;TNP2;LHX4;ZDHHC1

CA7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CA7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CA7.

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  • Q&As

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        Q&As (7)

        Ask a question
        What distinguishes the enzymatic function of CA7 from other carbonic anhydrase family members? 12/02/2022

        CA7 facilitates the reversible hydration of carbon dioxide, but its specific kinetics might differ from other isoforms.

        How does CA7 contribute to cellular pH balance and metabolism? 11/08/2020

        CA7 aids in CO2 transport and pH regulation, playing a crucial role in metabolic processes.

        Have any diseases or conditions been associated with aberrant CA7 expression or activity? 12/26/2019

        Dysregulation or mutations in CA7 might influence metabolic balance in tissues, potentially impacting conditions related to liver function or metabolism.

        Are there compounds known to specifically inhibit CA7 activity? 12/13/2018

        While some general carbonic anhydrase inhibitors might affect CA7, isoform-specific inhibitors would require further research.

        In which specific human tissues is CA7 expression most prevalent? 04/28/2018

        CA7 is primarily expressed in the liver, among other tissues.

        What post-translational modifications are characteristic of CA7? 01/10/2018

        Potential modifications like phosphorylation or acetylation can be identified using techniques like mass spectrometry.

        Are there any genetic mutations in the CA7 gene known to influence its enzymatic functionality? 03/06/2017

        Specific mutations could alter CA7's enzyme kinetics or stability, requiring in vitro functional assays for verification.

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