ca5b

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ca5b

Official Full Name carbonic anhydrase VB, mitochondrial
Background Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide.They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.They show extensive diversity in tissue distribution and in their subcellular localization.CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA.It has a wider tissue distribution than CA VA, which is restricted to the liver.The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.
Synonyms CA5B; carbonic anhydrase VB, mitochondrial; carbonic anhydrase 5B, mitochondrial; Carbonate dehydratase VB; Carbonic anhydrase VB; CA VB; carbonic dehydratase; CA-VB
    • Species :
    • Human
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CA5B-0243H Recombinant Human CA5B Protein, GST-Tagged Wheat Germ GST
    Human CA5B-10623H Recombinant Human CA5B, GST-tagged E.coli GST
    Human CA5B-1125H Recombinant Human CA5B, His tagged E.coli His
    Human CA5B-2267H Recombinant Human CA5B Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CA5B-265HCL Recombinant Human CA5B cell lysate N/A
    Human CA5B-463H Recombinant Human CA5B Protein E.coli N/A
    Human CA5B-577H Recombinant Human CA5B Protein, His-tagged E.coli His
    Rat Ca5b-7838R Recombinant Rat Ca5b protein, His-tagged E.coli His
    Rat CAR5B-1135R Recombinant Rat CAR5B Protein Mammalian Cell His

    ca5b involved in several pathways and played different roles in them. We selected most pathways ca5b participated on our site, such as Metabolism, Nitrogen metabolism, Reversible hydration of carbon dioxide, which may be useful for your reference. Also, other proteins which involved in the same pathway with ca5b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism KCNC2; CYP3C1; ATP5L; COL4A3BP; ARL2; ELA2; NDUFAF5; ADHFE1; MAPK1IP1L; SLC26A1
    Nitrogen metabolism CA1; GLUD1; Car8; CAR7; CAR1; CA3; CA12; CAR6; GLULC; CA7
    Reversible hydration of carbon dioxide CA13; CA5B

    ca5b has several biochemical functions, for example, carbonate dehydratase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ca5b itself. We selected most functions ca5b had, and list some proteins which have the same functions with ca5b. You can find most of the proteins on our site.

    Function Related Protein
    carbonate dehydratase activity Car12; CA12; CA5A; Car9; CA4B; CA5; CAR1; Car8; Car2; CAR5A
    zinc ion binding BTR16; RNF115; MORC3B; RNF26; TRIML1; USP16; PHF14; KDM4A; FUS; MORC3

    ca5b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ca5b here. Most of them are supplied by our site. Hope this information will be useful for your research of ca5b.

    Durdagi, S; Scozzafava, G; et al. Inhibition of mammalian carbonic anhydrases I-XIV with grayanotoxin III: solution and in silico studies. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 29:469-475(2014).
    van Karnebeek, CD; Sly, WS; et al. Mitochondrial Carbonic Anhydrase VA Deficiency Resulting from CA5A Alterations Presents with Hyperammonemia in Early Childhood. AMERICAN JOURNAL OF HUMAN GENETICS 94:453-461(2014).

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