CA14

  • Official Full Name

    carbonic anhydrase XIV

  • Overview

    Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide.They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.They show extensive diversity in tissue distribution and in their subcellular localization.CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles.
  • Synonyms

    CA14; carbonic anhydrase XIV; carbonic anhydrase 14; CA 14; CA XIV; Carbonate dehydratase XIV; CAXIV; UNQ690/PRO1335; CA-XIV; carbonic dehydratase; CAR14; AW536446;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Rabbit
  • Wheat Germ
  • C
  • Myc
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CA14-10617H Recombinant Human CA14, GST-tagged E.coli GST 19-293a.a.
Human CA14-0236H Recombinant Human CA14 Protein, GST-Tagged Wheat Germ GST
Human CA14-262H Recombinant Human CA14 protein, His-tagged HEK293 His Ala16-Met290
Human CA14-2485H Recombinant human CA14, His-tagged E.coli His
Human CA14-2802HCL Recombinant Human CA14 cell lysate Human Cell N/A
Human CA14-269H Recombinant Human CA14 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human CAB11486RH Rabbit Anti-Human Carbonic Anhydrase XIV Monoclonal Antibody Rabbit N/A
Human CA14-118H Recombinant Human CA14 Protein, His-tagged HEK293 His 337
Human CA14-2030H Recombinant Human CA14 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CA14-0138H Recombinant Human CA14 Protein (Gly19-Met290), N-His-tagged E.coli N-His Gly19-Met290
Human CA14-2737HF Recombinant Full Length Human CA14 Protein, GST-tagged In Vitro Cell Free System GST 337 amino acids
Mouse Car14-822M Active Recombinant Mouse Car14 Protein, His-tagged HEK293 His
Mouse CAR14-2716M Recombinant Mouse CAR14 Protein Mammalian Cell His
Mouse CA14-3064MCL Recombinant Mouse CA14 cell lysate Human Cell N/A
Mouse CA14-1156M-B Recombinant Mouse CA14 Protein Pre-coupled Magnetic Beads HEK293
Mouse Car14-1960M Recombinant Mouse Car14 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse CA14-1156M Recombinant Mouse CA14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CAB11490RM Rabbit Anti-Mouse Carbonic Anhydrase 14 Monoclonal Antibody Rabbit N/A
Rhesus Macaque CA14-596R Recombinant Rhesus monkey CA14 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CA14-424R-B Recombinant Rhesus Macaque CA14 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CA14-424R Recombinant Rhesus Macaque CA14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish CA14-3586Z Recombinant Zebrafish CA14 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CA14 involved in several pathways and played different roles in them. We selected most pathways CA14 participated on our site, such as Nitrogen metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CA14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Nitrogen metabolismCA14;CA6;Car14;Car2;CA1;CA13;GLULB;GLUD1A;CAHZ

CA14 has several biochemical functions, for example, carbonate dehydratase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CA14 itself. We selected most functions CA14 had, and list some proteins which have the same functions with CA14. You can find most of the proteins on our site.

Function Related Protein
carbonate dehydratase activityCA15A;Car2;CA7;CA6;CA5A;CA12;Car4;CAHZ;CAR15
metal ion bindingHDAC7A;INSM1B;FEZF2;PCXB;ESRRGB;BMP1B;ADAR;SLC2A4RG;SCRT2

CA14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CA14 here. Most of them are supplied by our site. Hope this information will be useful for your research of CA14.

ZNF273

  • Reviews
  • Q&As

Customer Reviews (3)

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Reviews
08/19/2022

    Reliable source, ensures reproducibility in our research.

    11/10/2020

      Efficient services, optimize our protein-related studies.

      10/01/2020

        Responsive customer support, aids in problem-solving effectively.

        Q&As (7)

        Ask a question
        Are there any known small molecule modulators specific to CA14's activity? 10/16/2022

        Specific modulators can be identified through high-throughput screening assays targeting CA14 and validated using in vitro and in vivo models.

        What unique functional attributes differentiate CA14 from other carbonic anhydrase isoforms? 02/14/2022

        CA14's unique functional attributes can be discerned using comparative enzymatic assays and structural analyses against other isoforms.

        How do changes in cellular pH or ion concentrations influence CA14 activity? 09/26/2020

        Influence of pH or ions on CA14 can be analyzed using enzymatic assays under varying conditions and ion-sensitive probes.

        Are there any known disease associations where CA14 mutations or dysregulation play a pivotal role? 05/02/2020

        Disease associations can be determined through genetic studies, patient tissue analyses, and literature reviews focusing on CA14's relevance in pathological conditions.

        In what tissues or cell types is CA14 predominantly expressed, and how does this correlate with its physiological role? 09/17/2019

        Predominant tissue or cell-type expression can be determined using tissue microarrays, qPCR, or proteomic databases, correlating findings with potential physiological implications.

        What are the consequences of CA14 overexpression or knockdown in cellular and organismal models? 02/16/2018

        Consequences of overexpression or knockdown can be assessed using phenotypic analyses, cellular viability assays, and in vivo studies in organisms with altered CA14 expression.

        Are there specific cellular pathways where CA14 plays a crucial modulatory role? 07/15/2017

        CA14's role in cellular pathways can be explored using pathway enrichment analyses, proteomic studies, and pathway-specific assays in CA14-modified cells.

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