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Official Full Name carbonic anhydrase I
Background Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.
Synonyms CA1; carbonic anhydrase I; carbonic anhydrase 1; Car1; JW0122; CA 1; CA I; CA-I; CAB; CAH1_HUMAN; CAI; CAN; Car 1; Carbonate dehydratase I; Carbonic anhydrase B; Carbonic dehydratase; ECK0125; yadF; OTTHUMP00000227973; OTTHUMP00000227974; OTTHUMP00000227976; OTTHUMP00000227977; OTTHUMP00000227978; OTTHUMP00000227979; OTTHUMP00000227981; Car-1; AW555628
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • SUMO
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CA1-0227H Recombinant Human CA1 Protein, GST-Tagged Wheat Germ GST
    Human CA1-10612H Recombinant Human CA1, GST-tagged E.coli GST
    Human CA1-1677H Recombinant Human Carbonic Anhydrase I, His-tagged Human His
    Human CA1-179H Recombinant Human Carbonic Anhydrase I E.coli N/A
    Human CA1-2505H Recombinant Human Carbonic Anhydrase I, His-tagged E.coli His
    Human CA1-6515H Recombinant Human CA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CA1-7917HCL Recombinant Human CA1 293 Cell Lysate HEK293 N/A
    Human CA1-811H Recombinant Human CA1 Protein E.coli N/A
    Mouse CAR1-2711M Recombinant Mouse CAR1 Protein Mammalian Cell His
    Rat CA1-1347R Recombinant Rat CA1 Protein (2-261 aa), His-tagged Yeast His
    Rat CA1-375R Recombinant Rat CA1 Protein (2-261 aa), His-SUMO-tagged E.coli His/SUMO
    Rat CAR1-1131R Recombinant Rat CAR1 Protein Mammalian Cell His

    ca1 involved in several pathways and played different roles in them. We selected most pathways ca1 participated on our site, such as Nitrogen metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ca1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Nitrogen metabolism CA4B; CA12; CAHZ; CAR13; CA9; GLUD2; Car9; CA5; GLUD1; GLULB

    ca1 has several biochemical functions, for example, arylesterase activity, carbonate dehydratase activity, hydro-lyase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ca1 itself. We selected most functions ca1 had, and list some proteins which have the same functions with ca1. You can find most of the proteins on our site.

    Function Related Protein
    arylesterase activity C20orf3; PON2; APMAP; CA2; Car2; PON3; CA1; CAR1; PON1
    carbonate dehydratase activity CA2; CA15C; Car12; CA12; CAR3; CA4A; CA4; CA5A; Car8; Car2
    hydro-lyase activity HIBCH; CA1; CAR1; L3HYPDH
    protein binding METTL9; HELZ2; CXCR4; TRIM25; HSPB7; NEK11; SHANK3; AVPI1; PMF1; RNF31
    zinc ion binding TAB3; APOBEC1; LONRF2; BRPF1; RORB; PHF21A; DPF2L; LMX1BB; FTR67; RNF26

    ca1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ca1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ca1.

    TFCP2; HSD17B7; MAPK6

    Czeh, B; Varga, ZKK; et al. Chronic Stress Reduces the Number of GABAergic Interneurons in the Adult Rat Hippocampus, Dorsal-Ventral and Region-Specific Differences. HIPPOCAMPUS 25:393-405(2015).
    Wang, WC; Cheng, CF; et al. Immunohistochemical Localization of DPP10 in Rat Brain Supports the Existence of a Kv4/KChIP/DPPL Ternary Complex in Neurons. JOURNAL OF COMPARATIVE NEUROLOGY 523:608-628(2015).

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