CA1

  • Official Full Name

    carbonic anhydrase I

  • Overview

    Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.
  • Synonyms

    CA1; carbonic anhydrase I; carbonic anhydrase 1; Car1; JW0122; CA 1; CA I; CA-I; CAB; CAH1_HUMAN; CAI; CAN; Car 1; Carbonate dehydratase I; Carbonic anhydrase B; Carbonic dehydratase; ECK0125; yadF; OTTHUMP00000227973; OTTHUMP00000227974; OTTHUMP00000227976; OTTHUMP00000227977; OTTHUMP00000227978; OTTHUMP00000227979; OTTHUMP00000227981; Car-1; AW555628;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Capsicum annuum (Bell pepper)
  • Human
  • Mouse
  • Rat
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Strep
  • His|SUMO
  • SUMO
  • Myc
  • DDK
  • MYC
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CA1-811H Recombinant Human CA1 Protein E.coli N/A
Human CA1-179H Recombinant Human Carbonic Anhydrase I E.coli N/A
Human CA1-1677H Recombinant Human Carbonic Anhydrase I, His-tagged Human His
Human CA1-10612H Recombinant Human CA1, GST-tagged E.coli GST 1-261a.a.
Human CA1-0227H Recombinant Human CA1 Protein, GST-Tagged Wheat Germ GST
Human CA1-2505H Recombinant Human Carbonic Anhydrase I, His-tagged E.coli His 1-261aa
Human CA1-7917HCL Recombinant Human CA1 293 Cell Lysate HEK293 N/A
Human CA1-2731HF Recombinant Full Length Human CA1 Protein, GST-tagged In Vitro Cell Free System GST 261 amino acids
Human CA1-0468H Recombinant Human CA1 Protein (Ala2-Phe261), N-His-tagged E.coli N-His Ala2-Phe261
Human CA1-0274H Recombinant Human CA1 Protein (M1-F261), Tag Free E.coli No tag M1-F261
Human CA1-6515H Recombinant Human CA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CA1-0469H Recombinant Human CA1 Protein (Full Length), N-His-tagged E.coli N-His Full Length
Human CA1-2614H Recombinant Human CA1 protein, His-SUMO-tagged E.coli His-SUMO 2-261aa
Human CA1-0275H Recombinant Human CA1 Protein (M1-F261), His/Strep tagged E.coli His/Strep M1-F261
Human CA1-5356H Recombinant Human CA1 protein, His-tagged Yeast His 2-261aa
Human CA1-2503H Recombinant Human CA1 protein(11-260 aa), C-His-tagged E.coli C-His 11-260 aa
Mouse Car1-7864M Recombinant Mouse Car1 protein, His-tagged E.coli His Asp15~Gln223 (Accession # P13634)
Mouse CAR1-2711M Recombinant Mouse CAR1 Protein Mammalian Cell His
Mouse CA1-1151M-B Recombinant Mouse CA1 Protein Pre-coupled Magnetic Beads HEK293
Mouse CA1-1151M Recombinant Mouse CA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Car1-764M Recombinant Mouse Car1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat CAR1-1131R Recombinant Rat CAR1 Protein Mammalian Cell His
Rat CA1-715R-B Recombinant Rat CA1 Protein Pre-coupled Magnetic Beads HEK293
Rat CA1-1347R Recombinant Rat CA1 Protein (2-261 aa), His-tagged Yeast His 2-261 aa
Rat Ca1-2615R Recombinant Rat Ca1 protein, His-tagged E.coli His 2-261aa
Rat CA1-375R Recombinant Rat CA1 Protein (2-261 aa), His-SUMO-tagged E.coli His/SUMO 2-261 aa
Rat CA1-715R Recombinant Rat CA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Capsicum annuum (Bell pepper) RFL22792CF Recombinant Full Length Capsicum Annuum Beta-Carotene Hydroxylase 1, Chloroplastic(Ca1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (9-315)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CA1 involved in several pathways and played different roles in them. We selected most pathways CA1 participated on our site, such as Nitrogen metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Nitrogen metabolismCA3;CAR15;CAR5A;Car8;CPS1;CA4A;CA13;CAR13;GLULB

CA1 has several biochemical functions, for example, arylesterase activity, carbonate dehydratase activity, hydro-lyase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CA1 itself. We selected most functions CA1 had, and list some proteins which have the same functions with CA1. You can find most of the proteins on our site.

Function Related Protein
arylesterase activityPON2;CAR1;Car2;CA1;APMAP;C20orf3;PON3;PON1;CA2
carbonate dehydratase activityCar8;CA15A;CA8;CAR1;CA4;CA5;Car4;Car14;CA6
hydro-lyase activityL3HYPDH;HIBCH;CAR1;CA1
protein bindingTARDBP;ACTN4;RCBTB2;HSFY1;TBXAS1;KIRREL3;GZMA;ZNF10;TRPC4AP
zinc ion bindingADAMTS9;PIAS3;BHMT;PITRM1;MTA2;NR2F6B;NR1I3;MT1;RERE

CA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CA1.

TFCP2; HSD17B7; MAPK6

Research Area

Related articles

Czeh, B; Varga, ZKK; et al. Chronic Stress Reduces the Number of GABAergic Interneurons in the Adult Rat Hippocampus, Dorsal-Ventral and Region-Specific Differences. HIPPOCAMPUS 25:393-405(2015).
Wang, WC; Cheng, CF; et al. Immunohistochemical Localization of DPP10 in Rat Brain Supports the Existence of a Kv4/KChIP/DPPL Ternary Complex in Neurons. JOURNAL OF COMPARATIVE NEUROLOGY 523:608-628(2015).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
How does CA1 protein's phosphorylation change during synaptic stimulation? 04/13/2022

CA1 protein's phosphorylation changes with synaptic stimulation, impacting its function.

What impact do post-translational modifications have on CA1 protein's subcellular localization and synaptic function? 08/22/2021

Post-translational modifications can alter CA1 protein's subcellular localization and synaptic function.

How do epigenetic factors influence CA1 protein's function in memory formation? 07/12/2021

Epigenetic factors influence CA1 protein's function in memory formation via modifications.

What is CA1 protein's specific role in regulating memory processes? 07/27/2018

CA1 protein plays a specific role in memory processes, aiding memory formation.

What is CA1 protein's specific role in regulating synaptic plasticity? 01/07/2018

CA1 protein regulates synaptic plasticity by modulating synaptic strength.

How do genetic factors regulate CA1 protein expression? 10/13/2017

Genetic factors regulate CA1 protein expression, affecting its levels.

Can we develop a high-resolution imaging technique to monitor CA1 protein dynamics within dendritic spines? 10/03/2016

Developing high-resolution imaging techniques for monitoring CA1 protein dynamics is feasible.

Customer Reviews (3)

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Reviews
05/19/2022

    Swift protein purification, expedites our research timelines.

    04/23/2021

      Efficient analysis, aids our understanding of protein function.

      09/17/2020

        Reliable protein assays, critical for our scientific investigations.

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