Cytokine and Receptor Analysis

Creative BioMart has a revolutionary new platform, which is designed for enrichment and highly sensitive detection of cytokine-secreting cells. We also offer a wide selection of tools to study cytokines, chemokines, and their receptors. These include active proteins, antibodies, ELISAs, Multiplex Assays, Primers, and more.

Our new platform allows:

• Magnetic enrichment of viable cytokine-secreting cells for enhanced detection sensitivity of one antigen-specific T cell per million cells.
• Isolated cells can immediately be used for downstream applications, e.g., cell culture and analysis.
• Analysis of cytokine secretion at single-cell level.
• Simultaneous phenotyping of cytokine-secreting cells for detailed information on subsets and activation status.
• Detection of co-expression of different cytokines.
• Simultaneous staining with peptide tetramers for analysis of cell function

Creative BioMart offers a suite of singleplex and multiplex cytokine and chemokine kits for a wide range of species:

Human Cytokines: Basic FGF, CTACK, Eotaxin, Eotaxin-3, G-CSF, GM-CSF, GRO-α, HGF, ICAM-1, IFNg, IFN-α2, IFN-γ, IL-10, IL-12 (p70), IL-13, IL-15, IL-16, IL-17, IL-17A, IL-18, IL-1ra, IL-1α, IL-1β, IL-2, IL-2Rα, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IP-10, LIF, MCP-1 (MCAF), MCP-3, MCP-4, M-CSF, MDC, MIF, MIG, MIP-1α, MIP-1β, PDGF-BB, RANTES, SCF, SCGF-β, SDF-1α, TARC, TNF-α, TNF-β, TRAIL, VCAM-1, VEG, VEGF, β-NGF;

Mouse Cytokines: Basic FGF, CD40, Eotaxin, G-CSF, GM-CSF, IFNg, IFN-γ, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-17, IL-17A, IL-17F, IL-18, IL-1α, IL-1β, IL-2, IL-21, IL-22, IL-3, IL-4, IL-5, IL-6, IL-9, KC/GRO/CINC, MCP-1 (MCAF), MIP-1α, MIP-1β, MIP-2, PDGF-BB, RANTES, TNF-α, VEGF;

RAT Cytokines: EPO, G-CSF, GM-CSF, GRO/KC, IFN-γ, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-17, IL-17A, IL-18, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IP-10, MCP-1, M-CSF, MIP-1α, MIP-2, MIP-3α, RANTES, TNF-α, VEGF.

Human chemokines: 6Ckine/CCL21, BCA-1/CXCL13, CTACK/CCL27, ENA-78/CXCL5, Eotaxin/CCL11, Eotaxin-2/CCL24, Eotaxin-3/CCL26, Fractalkine/CX3CL1, GCP-2/CXCL6, GM-CSF, Gro-α/CXCL1, Gro-β/CXCL2, I-309/CCL1, IFN-ϒ, IL-10, IL-16, IL-1β, IL-2, IL-4, IL-6, IL-8/CXCL8, IP-10/CXCL10, I-TAC/CXCL11, MCP-1/CCL2, MCP-2/CCL8, MCP-3/CCL7, MCP-4/CCL13, MDC/CCL22, MIF, MIG/CXCL9, MIP-1α/CCL3, MIP-1δ/CCL15, MIP-3α/CCL20, MIP-3β/CCL19, MPIF-1/CCL23, SCYB16/CXCL16, SDF-1α+β/CXCL12, TARC/CCL17, TECK/CCL25, TNF-α.

Our new platform enables the detection of inflammatory biomarkers in single and multiplex formats. As the next generation of electrochemiluminescence detection, Creative BioMart offers cytokine and chemokine assays that

• Ultra-low detection limits;
• Four logs of linear dynamic range are provided;
• Minimal sample volumes are required;
• Easily handle complex matrices.