Cancer marker is also called tumor marker, tumor biomarker or cancer biomarker. Cancer marker or cancer marker refers to endogenous proteins or metabolites that are indicative of the presence of cancer, progression characteristics and response to therapies in the body. Most cancer markers are produced by normal cells as well as by cancer cells. However, they are expressed at a much higher level when cancer occurs. Thus a biomarker may be possible to indicate the presence of cancer for cancer diagnosis, prognosis and epidemiology. Currently cancer diagnosis and prognosis are dependent on genetic, epigenetic and imaging biomarkers. These biomarkers are present in the blood, plasma and/or serum in an elevated level in the presence of cancerous cells. Biomarkers are widely used in cancer research to determine the seriousness of cancer in a patient, usually determined by the level of cancers cells in the body. They are also helpful in determining the patient response to a particular treatment helping physicians to plan out the best phases of treatment. Cancer markers also help to monitor the effect of the treatment for patients, indicating the effectiveness of the treatment over time. The current image based tests such as CT and MRI are highly costly. Cancer markers are gaining a lot of interest as it has the ability to detect cancerous cells at an early stage, resulting in lower cost for patient care and improving survival rates.
During the last decade, with the exploration in carcinogenesis and tumor progression field, a large number of potential cancer markers have been found. However, only few cancer markers are acceptable by FDA. As a primary manufacturer of recombinant proteins, Creative Biomart provides cancer markers related recombinant proteins of several sources, grades and formulations for research applications.