ACRBP
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Official Full Name
acrosin binding protein
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Overview
The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon. -
Synonyms
ACRBP; acrosin binding protein; acrosin-binding protein; cancer/testis antigen 23; CT23; OY TES 1; proacrosin binding protein sp32; SP32; cancer/testis antigen OY-TES-1; OY-TES-1; FLJ51160;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- HIS
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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| Human | ACRBP-155H | Recombinant Human ACRBP Protein, HIS-tagged | E.coli | HIS |
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| Human | ACRBP-187H | Recombinant Human ACRBP Protein, GST-Tagged | Wheat Germ | GST |
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| Human | ACRBP-9080HCL | Recombinant Human ACRBP 293 Cell Lysate | HEK293 | N/A |
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| Human | ACRBP-811HF | Recombinant Full Length Human ACRBP Protein, GST-tagged | In Vitro Cell Free System | GST | 543 amino acids |
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| Mouse | ACRBP-1219M | Recombinant Mouse ACRBP Protein | Mammalian Cell | His |
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| Mouse | ACRBP-267M-B | Recombinant Mouse ACRBP Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | ACRBP-267M | Recombinant Mouse ACRBP Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | ACRBP-465R | Recombinant Rat ACRBP Protein | Mammalian Cell | His |
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| Rat | ACRBP-121R | Recombinant Rat ACRBP Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | ACRBP-121R-B | Recombinant Rat ACRBP Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ACRBP Related Articles
ACRBP involved in several pathways and played different roles in them. We selected most pathways ACRBP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ACRBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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ACRBP has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by ACRBP itself. We selected most functions ACRBP had, and list some proteins which have the same functions with ACRBP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | GM4179;TSGA10;ZDBF2;DEFA23;ARMC5;VSTM2B;TNNI1C;LRRC8D;SYNGR2B |
ACRBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACRBP here. Most of them are supplied by our site. Hope this information will be useful for your research of ACRBP.
- Q&As
- Reviews
Q&As (10)
Ask a questionThe ACRBP gene expression is regulated by multiple factors during spermatogenesis, including androgens and retinoic acid.
The Cys-His repeats in the ACRBP protein are thought to be involved in the binding of acrosin, a protease involved in sperm function.
Mutations in the ACRBP gene have been associated with male infertility, and dysregulated expression of the gene has been implicated in several reproductive disorders.
The ACRBP protein contains several domains, including a signal peptide, a N-terminal proline-rich domain, a central domain with multiple repeats of a Cys-His motif, and a C-terminal domain with a conserved CUB (complement C1r/C1s, Uegf, and bone morphogenetic protein-1) domain.
The ACRBP gene product is involved in the regulation of acrosin activity during spermatogenesis.
The ACRBP protein can undergo several post-translational modifications, including phosphorylation, glycosylation, and proteolytic cleavage.
The ACRBP protein is transported and localized within the cell by a signal peptide that targets it to the endoplasmic reticulum and Golgi apparatus.
The tissue distribution of the ACRBP gene in non-human species varies depending on the species, but it is primarily expressed in the male reproductive system.
The CUB domain of the ACRBP protein is thought to be involved in protein-protein interactions with other molecules involved in sperm function.
The ACRBP gene is primarily expressed in the testis, specifically in the seminiferous tubules and epididymis.
Customer Reviews (5)
Write a reviewThe manufacturer's products have good batch control, and the quality of the protein is stable every time.
The samples provided by the manufacturer make it easier for me to choose the most suitable protein.
The manufacturer provides comprehensive after-sales service, and I am very satisfied with this.
The quality of the manufacturer's products is consistent, and I have always been their loyal customer.
The protein price is reasonable, and I feel that it is worth the money.
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