ADCY4 Protein, adenylate cyclase 4


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Official Full Name adenylate cyclase 4
Synonyms ADCY4; adenylate cyclase 4; adenylate cyclase type 4; AC4; ADCY4_HUMAN; Adenylate cyclase type IV; Adenylyl cyclase 4; Adenylyl cyclase; ATP pyrophosphate lyase 4; ATP pyrophosphate lyase; ATP pyrophosphate-lyase 4; mKIAA4004
    • Species :
    • Mouse
    • Rat
    • Source :
    • E.coli
    • E.Coli or Yeast
    • Tag :
    • GST
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Adcy4-6926M Recombinant Mouse Adcy4 protein, His & T7-tagged E.coli His/T7
    Rat Adcy4-3175R Recombinant Rat Adcy4, GST-tagged E.Coli or Yeast GST

    ADCY4 involved in several pathways and played different roles in them. We selected most pathways ADCY4 participated on our site, such as Purine metabolism, Rap signaling pathway, Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADCY4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Purine metabolism AK3; PKM; IMPDH1; PDE8B; PDE2A; POLR3G; NT5C2; ENTPD4; POLA2; GMPS
    Rap signaling pathway CDH1; INSR; FGF21; GRIN2B; Itgam&Itgb2; VEGFB; FGF4; MAPK12; ACTG1; KIT
    Calcium signaling pathway HTR2B; PPP3CC; CACNA1D; NOS2; DRD1B; CALM; ATP2B1; PHKG2; ATP2A2A; CHRM5A
    cGMP-PKG signaling pathway PPP1CB; MEF2C; GATA4; PLCB2; ATP1A4; ATP1A2; ATP1B2; SLC8A2; PRKG1; KCNJ8
    cAMP signaling pathway CALML5; PTGER3; MAP2K2; RAC1; MLLT4; HTR4; NFKBIA; ATP1A2; GRIN2D; ATP1A3
    Chemokine signaling pathway RAC2; PRKACG; CXCR1; WAS; CCL23; XCR1; GNB3; STAT5B; FGR; CX3CL1
    Phospholipase D signaling pathway GRB2; PIP5K1A; PIK3CG; TSC1; CYTH4; RALB; PIK3CD; FCER1G; AGTR1B; ARF6
    Oocyte meiosis INSB; CDC23; PPP3R2; CDC26; RPS6KA1; Adcy4; PPP2R5EA; PPP1R2P9; PLCZ1; PPP3CCB
    Adrenergic signaling in cardiomyocytes TPM2; SCN1BB; PPP2R2CA; CACNB3; ATP1A3B; ADCY1; ACTC1A; CALM1B; AGTR1; ADCY7
    Vascular smooth muscle contraction PRKCBB; CALM3B; ROCK2A; EDNRAA; PRKACAA; MYL9B; AGTR1A; ROCK2B; CACNA1D; PPP1R12C
    Platelet activation P2RY1; GNAI3; PRKACG; RHOA; MAPK11; TBXAS1; GP1BB; COL24A1; ITGA2B; GP5
    Circadian entrainment MTNR1A; CAMK2A; GNGT1; KCNJ6; KCNJ5; RPS6KA5; GNG3; KCNJ9; GUCY1B3; GRIA3
    Retrograde endocannabinoid signaling MAPK1; GNAI2; ABHD6; PRKACA; GNB3; GNG12; MAPK13; GNG11; GRM1; PLCB4
    Glutamatergic synapse GNB2; GRM1; PLCB4; GNAI1; GRIA2; PLA2G4A; HOMER1; GNG12; GLS2; PLCB1
    Cholinergic synapse CREB3L3; CHRM3; ACHE; GNB3; PRKACB; AKT2; PIK3CB; NRAS; ATF4; GNA11
    Taste transduction TAS2R120; TAS2R124; PRKACB; GNG3; TAS2R106; TAS1R2; TAS2R129; ASIC2; TAS2R125; TAS1R1
    Inflammatory mediator regulation of TRP channels Adcy4; TRPA1; HTR2C; PTGER2; TRPV2; PLCB1; PRKCG; PIK3CB; CYP2C50; HRH1
    Insulin secretion RAPGEF4; ATP1B2; PCLO; ATP1A2; KCNN4; PRKACA; ATP1A4; RAB3A; PRKACB; CREB3L2
    GnRH signaling pathway ITPR1; MAPK8; MMP14; MAP3K4; HRASB; SRC; PRKCBA; ATF4B1; MAP2K2A; CACNA1D
    Ovarian steroidogenesis IGF1R; INS; HSD3B5; SCARB1; IGF1; HSD3B2; PLA2G4A; Adcy4; INS1; LDLR
    Progesterone-mediated oocyte maturation ARAF; PPP1R2P9; ANAPC11; HSP90AA1.2; PDE3B; CDK1; RAF1A; CPEB3; MAPK12A; BRAF
    Estrogen signaling pathway GRM1; RAF1; PIK3R1; FKBP4; ITPR1; CALML3; PIK3CA; ITPR3; FOS; SHC3
    Melanogenesis FZD8A; HRASA; MAPK1; CAMK2B; TCF7L2; CAMK2D2; PLCB3; HRASB; TYRP1; FZD6
    Thyroid hormone synthesis GSR; PLCB1; TSHR; PAX8; ATP1B3; ATP1B2; ITPR3; GPX6; PLCB2; FXYD2
    Oxytocin signaling pathway PIK3CA; MYLK; MAP2K5; CAMKK1; CCND1; NFATC2; PLCB4; CAMK4; CAMK1D; PPP1CB
    Regulation of lipolysis in adipocytes IRS2; PRKG2; TSHR; IRS4; PLIN1; PIK3CA; PDE3B; PIK3CG; PNPLA2; LOC100328615
    Aldosterone synthesis and secretion GNAS; NPR1; ADCY3; PRKD1; AGTR1; LIPE; CAMK2A; ADCY7; PRKACA; ATF2
    Salivary secretion PLCB4; LYZ1; GNAQ; PLCB3; CST1; CST5; PRKCG; CALM3; GUCY1B3; ATP2B1
    Gastric acid secretion MYLK; ATP1B4; Adcy4; CALM1; PRKCA; KCNQ1; ATP1B2; ATP1B1; GAST; EZR
    Pancreatic secretion LOC780933; CPB2; PRSS1; CD38; PLCB4; GNAS; Slc4a2; CCKAR; AMY2A; SCTR
    Bile secretion ATP1B1; PRKACB; ADCY6; ATP1A3; ABCB4; KCNN2; SLCO1A2; SLC22A1; PRKACA; ABCB11
    Morphine addiction GABRD; PDE3A; GNAI1; GABRG1; GABRB1; PDE7B; GABRA5; GABRQ; GNAS; PDE3B
    HTLV-I infection GM-CSF; CD40; PDGFRB; POLE3; TBP; TBPL1; FZD3; GPS2; PDGFB; ZFP36
    Pathways in cancer Pdgfa&Pdgfb; PDGFA; TPR; HIF1A; RALBP1; FZD1; TGFA; TCEB1; PLCB2; STAT5B
    Dilated cardiomyopathy SGCB; CACNB3; ITGB5; TPM4; ITGAV; ITGA4; ITGB3; MYBPC3; CACNG1; ITGB4

    ADCY4 has several biochemical functions, for example, ATP binding, G-protein beta/gamma-subunit complex binding, adenylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADCY4 itself. We selected most functions ADCY4 had, and list some proteins which have the same functions with ADCY4. You can find most of the proteins on our site.

    Function Related Protein
    G-protein beta/gamma-subunit complex binding GNAI2A; GNA13; GNAS; PIK3R5; GNAT2; GNA13B; GNAZ; ADORA1; GNAI2B; GNAV1
    adenylate cyclase activity ADCY1; ADCY1B; ADCY9; GNAS; ADCY8; Adcy4; ADCY1A; ADCY7; ADCY6; ADCY3
    metal ion binding ZBED4; KLF12; ZRANB1B; ADHFE1; SMAD9; RHEBL1; KCND1; BCL11B; LONRF1L; CPPED1
    nucleotide binding CSTF2T; MAPK12A; PRKACAA; PRAC; SAFB; HNRPLL; ACTR1; ATP2B1; CDK14; HIPK3B

    ADCY4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADCY4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADCY4.

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