apoa4
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  • Official Full Name
  • apolipoprotein A-IV
  • Background
  • Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro. [provided by RefSeq, Jul 2008]
  • Synonyms
  • APOA4; apolipoprotein A-IV; apo-AIV; apoA-IV; apolipoprotein A4;
Cat.#:APOA4-1332MTag:His
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse APOA4 Protein (21-395 aa), His-tagged
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Cat.#:APOA4-2037HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human APOA4 protein, His & GST-tagged
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Cat.#:APOA4-30HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human APOA4, His-tagged
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Cat.#:APOA4-692HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human APOA4 protein, GST-tagged
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Cat.#:APOA4-766HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human APOA4 Protein, His-tagged
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Cat.#:APOA4-9749HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human APOA4, GST-tagged
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Cat.#:APOA4-1782MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse APOA4 Protein
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Cat.#:Apoa4-2038MTag:His/S
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Apoa4 protein, His & S-tagged
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Cat.#:Apoa4-2039MTag:His/S
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Apoa4 protein, His & S-tagged
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Cat.#:APOA4-719RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat APOA4 Protein
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Cat.#:Apoa4-720RTag:His/GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Apoa4 protein, His/GST-tagged
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Cat.#:APOA4-6498CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken APOA4
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Cat.#:APOA4-2036CTag:His/T7
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle APOA4 protein, His & T7-tagged
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Cat.#:APOA4-2040PTag:His
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig APOA4 protein, His-tagged
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Cat.#:APOA4-3567PTag:His
Source (Host):Mammalian CellsSpecies:Pig
Product nameRecombinant Pig APOA4, His-tagged
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Cat.#:ApoA4-68HTag:
Source (Host):Species:Human
Product nameNative Human Apolipoprotein AIV
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Cat.#:APOA4-8788HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human APOA4 293 Cell Lysate
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Involved Pathway

APOA4 involved in several pathways and played different roles in them. We selected most pathways APOA4 participated on our site, such as Fat digestion and absorption, Vitamin digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with APOA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Fat digestion and absorption
Cel; DGAT2; PLA2G3; PNLIPRP2; ABCA1; DGAT1; APOA4; SCARB1; PLA2G2F; APOB
Vitamin digestion and absorption
SLC46A1; GIF; APOB; FOLH1; SLC19A1; RBP2; MMACHC; PNLIP; LRAT; BTD

Protein Function

APOA4 has several biochemical functions, for example, antioxidant activity, cholesterol binding, cholesterol transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by APOA4 itself. We selected most functions APOA4 had, and list some proteins which have the same functions with APOA4. You can find most of the proteins on our site.
Function
Related Protein
Function antioxidant activity
Related Protein TRP53INP1; KDM3B; PRDX2; HP; APOA4; CAT; SELS; PRDX6; TP53INP1; APOM
Function cholesterol binding
Related Protein APOEA; APOA2; APOC3; OSBPL8; TSPO2; PTCH1; SOAT1; APOA4B.2; CETP; APOEB
Function cholesterol transporter activity
Related Protein APOA4; APOEA; ABCA4A; APOA4B.2; ABCA7; ABCA13; ABCA1B; APOA5; ABCA4; ABCG1
Function copper ion binding
Related Protein SOD3A; PRND; ABP1; P2RX4; SNAI3; METTL17; S100A5; CUTC; P2RX2; DCT
Function lipid binding
Related Protein TRIP10; ACOT11B; APOA4B.1; LTC4S; PSAP; MARK2; UNC119B; VCP; PFN4; RASGRP2
Function lipid transporter activity
Related Protein APOL3; SLCO2A1; APOA4; ATP8B1; GM2A; VTG4; APOC4; APOM; VTG6; VTG1
Function phosphatidylcholine binding
Related Protein SERPINA5; APOA1A; VPS24; APOA2; RPE65; PCTP; CETP; GPR12; APOA4B.2; GPR119
Function phosphatidylcholine-sterol O-acyltransferase activator activity
Related Protein APOA5; APOA1A; APOA4B.1; APOEB; APOC1; APOA1; APOA2; APOA4; APOA4B.2; APOE
Function protein binding
Related Protein PSEN1; TDRKH; HHLA3; KLF11; INO80; GNB2; OTUD7B; GRB7; CERK; NTF3
Function protein homodimerization activity
Related Protein HSPB6; Anks6; CD200; RAB11FIP4; TDG; NR2C1; SMAD2; SMAD4; JAM3; IL6ST

Interacting Protein

APOA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of APOA4.
NR1D1; d-mannose; g6pc_human_gene; ALB

APOA4 Related Articles

Tokuhara, D; Nochi, T; et al. Specific Expression of Apolipoprotein A-IV in the Follicle-Associated Epithelium of the Small Intestine. DIGESTIVE DISEASES AND SCIENCES 59:2682-2692(2014).
Zhao, HH; Yang, F; et al. Label Free Proteome Analysis of Plasma from Unstable Angina with Blood Stasis Syndrome Patients. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 31:285-292(2010).