• Official Full Name
  • Bromodeoxyuridine
  • Background
  • Bromodeoxyuridine (5-bromo-2-deoxyuridine, BrdU) is a synthetic nucleoside which is an analogue of thymidine. BrdU is commonly used in the detection of proliferating cells in living tissues. BrdU can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. Antibodies specific to BrdU can then be used to detect the incorporated chemical; thus indicating cells that were actively replicating their DNA. Binding of the antibody requires denaturation of the DNA by heat or acid.
  • Synonyms
  • Bromodeoxyuridine; 5-bromo-2'-deoxyuridine; BrdU; BUdR; BrdUrd

BrdU Related Articles

Yu, Q; Liu, LZ; et al. SDF-1 alpha/CXCR4 Axis Mediates The Migration of Mesenchymal Stem Cells to The Hypoxic-Ischemic Brain Lesion in A Rat Model. CELL JOURNAL 16:440-447(2015).
van der Heide, LP; Wijchers, PJEC; et al. FoxK2 is Required for Cellular Proliferation and Survival. JOURNAL OF CELLULAR PHYSIOLOGY 230:1013-1023(2015).