• Official Full Name
  • C1q and tumor necrosis factor related protein 6
  • Background
  • Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.
  • Synonyms
  • ZACRP6; C1q and tumor necrosis factor related protein 6; C1QT6_HUMAN; C1QTNF6; Complement C1q tumor necrosis factor related protein 6; Complement C1q tumor necrosis factor-related protein 6; CTRP 6; CTRP6; OTTHUMP00000197772; OTTHUMP00000197774; PRO1151; UNQ581; complement-c1q tumor necrosis factor-related protein 6
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human C1QTNF6, His-tagged
Source (Host):HEK293Species:Human
Product nameRecombinant Human C1QTNF6, FLAG-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat C1QTNF6 Protein
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human C1QTNF6, His-tagged
Source (Host):Species:Human
Product nameRecombinant Human C1QTNF6 293 Cell Lysate

Protein Function

C1QTNF6 has several biochemical functions, for example, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C1QTNF6 itself. We selected most functions C1QTNF6 had, and list some proteins which have the same functions with C1QTNF6. You can find most of the proteins on our site.
Related Protein
Function identical protein binding
Related Protein S100A1; LDHA; CALHM1; ROBO1; RELA; TNF; RBM10; CCDC155; UGP2; TRP53
Function protein binding
Related Protein STAG1; PSMB2; SGK1; C19orf10; STARD10; CLPP; NHEJ1; PTPN11; MVK; cgr2b

Interacting Protein

C1QTNF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C1QTNF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of C1QTNF6.
SGTA; Ring1; PML; ANAPC15; Ppp6r1; Mad2l1bp; Ndel1; VPS16; Cenph

C1QTNF6 Related Articles

Zhao, SX; Xue, LQ; et al. Robust evidence for five new Graves disease risk loci from a staged genome-wide association analysis. HUMAN MOLECULAR GENETICS 22:3347-3362(2013).
Johnen, G; Rozynek, P; et al. Cross-Contamination of a UROtsa Stock with T24 Cells - Molecular Comparison of Different Cell Lines and Stocks. PLOS ONE 8:-(2013).