camk2d
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  • Official Full Name
  • calcium/calmodulin-dependent protein kinase II delta
  • Background
  • The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
  • Synonyms
  • CAMK2D; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin dependent protein kinase (CaM kinase) II delta , CAMKD; calcium/calmodulin-dependent protein kinase type II subunit delta; CaMK-II delta subunit; caMK-II subunit delta; CaM-k
Cat.#:CAMK2D-0331HTag:GST
Source (Host):Insect CellSpecies:Human
Product nameRecombinant Human CAMK2D Protein, GST-Tagged
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Cat.#:CAMK2D-0332HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CAMK2D Protein, GST-Tagged
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Cat.#:CAMK2D-2281MTag:DDK
Source (Host):Insect cellsSpecies:Mouse
Product nameRecombinant Mouse CAMK2D Protein, DDK-tagged
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Cat.#:CAMK2D-27263THTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human CAMK2D
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Cat.#:CAMK2D-1102RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CAMK2D Protein
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Cat.#:CAMK2D-3360CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CAMK2D
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Cat.#:CAMK2D-266HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human CAMK2D, GST-tagged, Active
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Cat.#:CAMK2D-7878HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human CAMK2D 293 Cell Lysate
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Cat.#:CAMK2D-7879HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human CAMK2D 293 Cell Lysate
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Involved Pathway

CAMK2D involved in several pathways and played different roles in them. We selected most pathways CAMK2D participated on our site, such as ErbB signaling pathway, Calcium signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAMK2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ErbB signaling pathway
HBEGFB; MAPK8A; PAK2; PRKCA; GSK3AA; MAPK9; CAMK2D; RPS6KB1; CBLC; HBEGFA
Calcium signaling pathway
PLCG2; PPP3CCA; STIM1A; CACNA1H; MYLK4; ITPR3; ORAI1; PTAFR; PRKACBB; RYR1
cAMP signaling pathway
CAMK2D; PAK1; ACOX3; PRKACA; GRIN2D; FXYD1; HCAR3; GRIN1; AKT2; MAPK8
HIF- signaling pathway
MTOR; INS; EGLN1; TCEB2; PIK3CA; PIK3R5; CUL2; HMOX1; IL6R; HK1
Oocyte meiosis
CAMK2D; CALM4; CPEB1B; ADCY2B; SPDYB; PRKACAB; CCNB2; YWHAB; INS2; PPP2R5EB
Adrenergic signaling in cardiomyocytes
CACNG8; ATP1B1A; PIK3CA; GNAS; ATP1B2B; ATP1B2A; PPP2R5EA; MYH7; ACTC1A; PIK3R2
Wnt signaling pathway
CHD8; SMAD4; FZD6; NFATC4; CAMK2B; WNT4; CAMK2G1; FZD8B; FZD3; AXIN1
Circadian entrainment
NOS1AP; GRIA3; PER1; Adcy4; ADCYAP1R1; CALM1; MAPK1; CACNA1H; PER2; GRIN2C
Long-term potentiation
PPP1CA; CAMK2G; PPP3CC; HRAS; GNAQ; GRIA1; PLCB1; RAP1A; MAP2K2; PRKCB
Neurotrophin signaling pathway
BDNF; BAX; PIK3R5; MAPK10; NFKBIB; Fasl; CALM1; CALM2; PIK3R1; NTRK1
Cholinergic synapse
NRAS; PLCB1; MAPK3; ITPR1; GNG13; CAMK2A; KRAS; PRKCG; KCNQ2; CHRM2
Dopaminergic synapse
GNAO1; PPP2R2C; PRKACB; GNGT2; CALM1; PLCB4; MAPK8; ITPR3; PPP1CB; ARRB2
Olfactory transduction
OLFR486; OR1L6; OLFR469; PDE1B; CAMK2D; OLFR5; OLFR493; CALM1; OR2C1; OR10A5
Inflammatory mediator regulation of TRP channels
PLCG2; ASIC5; NGF; CALM3; ACCN3; CYP2C39; ACCN5; Adcy4; PIK3R5; BDKRB2
Insulin secretion
TRPM4; INS2; GPR119; KCNN3; GNA11; ATP1B1; GNAS; PLCB4; KCNMB4; SNAP25
GnRH signaling pathway
RAF1B; MAP3K4; MAP2K6; PRKCBB; RAF1; HBEGFA; MAP2K1; MAP2K7; GNAS; MAPK8B
Melanogenesis
FZD3A; FZD9; CAMK2D; CALM3A; TCF7L2; CREB3L3L; POMCA; GNAQ; GNAS; FZD3B
Oxytocin signaling pathway
MEF2C; PLA2G4C; PLA2G4F; NRAS; CD38; PPP1CA; PPP3CB; OXT; CAMKK2; CALML3
Glucagon signaling pathway
CALM1; PPP3CC; SMEK1; LDHC; PHKB; PRKAB2; CAMK2G; SLC2A1; CREB3L2; CPT1C
Aldosterone synthesis and secretion
PDE2A; CREB3L1; ITPR1; CAMK4; LDLR; PLCB4; KCNK9; ATF6B; CALML5; HSD3B1
Gastric acid secretion
MYLK3; ATP1B3; KCNJ2; PRKCA; CAMK2D; Car2; ATP1B2; ITPR3; KCNJ1; SST
Amphetamine addiction
PRKACA; MAOA; CAMK2A; CALML5; SLC14A2; CALM4; DRD1A; PDYN; GRIN2D; GRIN3B
Tuberculosis
HLA-DOB; IFNA4; NOS2; NFYA; IFNB1; NFKB1; IFNA17; RFXANK; FCGR2B; MAPK11
Proteoglycans in cancer
PIK3CG; MMP2; MAPK1; PRKCA; SOS1; FZD5; PDPK1; WNT8A; WNT9A; TFAP4
Glioma
PIK3CD; PDGFA; CALM2; CAMK2G; KRAS; IGF1; Pdgfa&Pdgfb; TGFA; HRAS; PIK3CB

Protein Function

CAMK2D has several biochemical functions, for example, ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CAMK2D itself. We selected most functions CAMK2D had, and list some proteins which have the same functions with CAMK2D. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein UBE2F; FLAD1; MCM6; FGFR1B; STYK1; TTLL4; HELLS; STK35L; KCNJ10; MOV10B.2
Function calmodulin binding
Related Protein MKNK1; MYO1E; MAPKAPK2A; PHKG1; SPATA17; RYR2; ATPIF1; MYO1C; CAMKK1; OBSCN
Function calmodulin-dependent protein kinase activity
Related Protein DCX; PNCK; CAMK4; CAMKK2; MAPKAPK2; CAMKK1; MKNK2; MAPKAPK5; CAMK2B; DAPK1
Function ion channel binding
Related Protein CALM1; PPP1R9B; PHPT1; FHL1; RNF207; ACTN2; KCNE4; PACS1; ACTN1; HTT
Function nitric-oxide synthase binding
Related Protein DNM2; CD74; SLC6A4; DNM3; CAV3; CALM1; SLC14A2; CDH2; ACTB; NOS1AP
Function protein binding
Related Protein HYPK; GALR2; SCARF1; DYRK1A; ACVR2B; MT1A; WDR12; MCPH1; UPF1; BUB3
Function protein homodimerization activity
Related Protein CREB3L3; ENPP1; LRP6; TYW5; ACCS; PYCARD; CCBL1; LSM1; ALDH5A1; GSTA4
Function protein serine/threonine kinase activity
Related Protein OBSCN; NEK5; MAPK14; MAPK4; PKN1; MAP2K6; STK36; EIF2AK2; STK38A; NUAK1
Function sodium channel inhibitor activity
Related Protein SCN1B; NEDD4; SLC14A2; PCSK9; CAMK2D; NEDD4L
Function titin binding
Related Protein CALM3; MYBPC3; CALM; ACTN2; ANKRD2; ANKRD1B; CAMK2D; ANKRD23; CALM1; OBSCN

Interacting Protein

CAMK2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAMK2D here. Most of them are supplied by our site. Hope this information will be useful for your research of CAMK2D.
SCN5A; TNPO2; DNAL4

CAMK2D Related Articles

Hidalgo, CG; Chung, CS; et al. The multifunctional Ca2+/calmodulin-dependent protein kinase II delta (CaMKII delta) phosphorylates cardiac titin's spring elements. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 54:90-97(2013).
Chen, QW; Edvinsson, L; et al. Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells. BMC CELL BIOLOGY 10:-(2009).