CAMK2D Protein, calcium/calmodulin-dependent protein kinase II delta


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Official Full Name calcium/calmodulin-dependent protein kinase II delta
Background The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
Synonyms CAMK2D; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin dependent protein kinase (CaM kinase) II delta , CAMKD; calcium/calmodulin-dependent protein kinase type II subunit delta; CaMK-II delta subunit; caMK-II subunit delta; CaM-k
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • DDK
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Camk2d-030M Recombinant Mouse Camk2d Protein, DDK-tagged Insect Cell DDK
    Mouse Camk2d-031M Recombinant Mouse Camk2d Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human CAMK2D-0331H Recombinant Human CAMK2D Protein, GST-Tagged Insect Cell GST
    Human CAMK2D-0332H Recombinant Human CAMK2D Protein, GST-Tagged Wheat Germ GST
    Human CAMK2D-266H Recombinant Human CAMK2D, GST-tagged, Active Sf9 Insect Cell GST
    Human CAMK2D-27263TH Recombinant Human CAMK2D N/A
    Human CAMK2D-7878HCL Recombinant Human CAMK2D 293 Cell Lysate HEK293 N/A
    Human CAMK2D-7879HCL Recombinant Human CAMK2D 293 Cell Lysate HEK293 N/A
    Mouse CAMK2D-2281M Recombinant Mouse CAMK2D Protein, DDK-tagged Insect Cell DDK
    Rat CAMK2D-1102R Recombinant Rat CAMK2D Protein Mammalian Cell His
    Chicken CAMK2D-3360C Recombinant Chicken CAMK2D Mammalian Cell His

    CAMK2D involved in several pathways and played different roles in them. We selected most pathways CAMK2D participated on our site, such as ErbB signaling pathway, Calcium signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAMK2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ErbB signaling pathway SOS1; PAK7; HRAS; MAP2K1; MYCB; STAT5A; HRASB; CBL; PIK3CB; PIK3R3
    Calcium signaling pathway BDKRB2; RYR1; PHKA2; TBXA2R; SLC25A6; SPHK1; RYR2; TNNC1; GRPR; TMEM8C
    cAMP signaling pathway CAMK2B; GRIA3; GPR81; PTCH1; OXTR; HHIP; FXYD1; MAPK8; BDNF; CNGA3
    HIF- signaling pathway PIK3CG; EGLN1; IL6; PRKCB; PIK3R2; HK3; INS; MKNK2; RELA; PIK3R5
    Oocyte meiosis PPP1CBL; PPP2R5C; CDC27; SMC1B; ANAPC1; YWHABL; PPP1CAA; MAPK1; SMC3; MAPK12
    Adrenergic signaling in cardiomyocytes MAPK13; GNAI1; ADCY6; PIK3R3A; VMHCL; SCN5A; MAPK12A; CREB5; PRKACG; SLC8A1
    Wnt signaling pathway WNT9B; SFRP2; CSNK1A1L; RHOAA; TCF7L1A; DVL3A; PLCB4; PRICKLE2B; TLE3A; FZD6
    Circadian entrainment RYR1; GNG13; PRKCA; GRIN2D; PRKACG; GRIA4; GNG12; MAPK1; GNG4; CAMK2D
    Long-term potentiation CALM3; GRM5; CAMK4; CALML3; RAP1B; RPS6KA6; RPS6KA2; CAMK2B; PRKCG; PPP3R2
    Neurotrophin signaling pathway AKT1; PIK3R2; RPS6KA5; CAMK4; IKBKB; SHC1; MAPK13; RAP1B; MAPK12; ARHGDIA
    Cholinergic synapse GNG8; CREB3; GNG3; Adcy4; CHRM1; KCNQ5; MAPK1; CHRNB2; PRKACG; PLCB2
    Dopaminergic synapse MAPK11; GNG5; GSK3B; KIF5C; GNG8; DDC; GNG7; CLOCK; PLCB1; PLCB4
    Olfactory transduction PDE1C; OR7D2; OR51B5; OLFR10; OLFR154; OR2C1; PRKACB; OR52B6; OLFR146; OLFR688
    Inflammatory mediator regulation of TRP channels CAMK2A; ACCN5; ASIC1; HTR2C; PLA2G6; GNAQ; PLCB3; CYP4A10; TRPA1; CAMK2B
    Insulin secretion ATP1A3; CAMK2B; PCLO; ATP1B4; INS1; ADCYAP1; CAMK2G; SNAP25; GIP; ATP1A4
    GnRH signaling pathway GNRHR4; PRKACAB; CALM1; MAPK12A; CALM4; GNAQ; GNRH2; MAP2K4A; PLD1A; PRKACB
    Melanogenesis CALM3; KIT; CALM; WNT16; PLCB2; WNT7A; HRAS; Kitl; CAMK2G; DVL1B
    Oxytocin signaling pathway PIK3R1; NPR2; PTGS2; CALM3; KRAS; RCAN1; MAPK7; ITPR1; GNAI2; CAMK2B
    Glucagon signaling pathway GCGR; PPP3CC; ACACB; PPP3R1; PKM; CREB3L1; PFKFB1; ACACA; PDHA2; PFKL
    Aldosterone synthesis and secretion HSD3B1; ATF6B; PRKCA; LDLR; CAMK1; PRKD3; PRKCE; DDX1; CACNA1H; CACNA1G
    Gastric acid secretion PLCB2; PRKACA; PRKACG; CA2; ITPR1; GNAI2; KCNJ16; ATP4A; MYLK4; ATP1A3
    Amphetamine addiction CREB3; CALM2; CAMK2G; CREB5; PPP3CB; CREB3L1; PDYN; CAMK4; SLC18A1; GRIN2B
    Tuberculosis IFNA1; FCGR2A; IFNA4; VDR; PPP3CA; ATP6AP1; Il23a; IFNA8; AKT1; IRAK2
    Proteoglycans in cancer ERBB4; ARHGEF1; CAV2; ACTG1; Casp3; SLC9A1; CTTN; MET; MAPK12; WNT9A
    Glioma TP53; PIK3R2; MAP2K2; PIK3CG; CAMK2G; KRAS; PIK3CD; AKT1; CALM4; SOS1

    CAMK2D has several biochemical functions, for example, ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CAMK2D itself. We selected most functions CAMK2D had, and list some proteins which have the same functions with CAMK2D. You can find most of the proteins on our site.

    Function Related Protein
    calmodulin binding RASGRF2; DDX5; CAMK2G1; GRIN1; MAPKAPK2A; SPHK1; CAMK2A; ATP2B4; PCDP1; MYO5A
    calmodulin-dependent protein kinase activity CAMK1G; PNCK; PTK2B; MYLK3; MAPKAPK5; MAPKAPK2; CAMK2D2; CAMKK2; CAMK2B1; MYLK2
    ion channel binding SLC14A2; PDE4D; NOS1; HSP90AB1; KCNH1; KCNIP2; YWHAH; CALM1; PPP1R9B; YES1
    nitric-oxide synthase binding CAMK2D; CD74; SLC6A4; DMD; ACTB; NOS1AP; CAV3; CDH2; SLC14A2; CAV1
    protein binding FOXP3; FCN2; ITGB7; TGOLN2; LCOR; NEDD9; TNFAIP1; RCN1; SGTB; TRPC4AP
    protein homodimerization activity NAGA; NR4A3; DST; TRIM8; Defa-rs7; HPGD; TPD52L2; CAMK2G; HSD17B4; ABCG1
    protein serine/threonine kinase activity PKMYT1; CSNK1A1; SBK3; RPS6KB2; CDC42BPG; ICK; CLK4; SGK2A; CSNK1DB; NUAK2
    sodium channel inhibitor activity NEDD4; CAMK2D; PCSK9; SCN1B; NEDD4L; SLC14A2

    CAMK2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAMK2D here. Most of them are supplied by our site. Hope this information will be useful for your research of CAMK2D.


    Hidalgo, CG; Chung, CS; et al. The multifunctional Ca2+/calmodulin-dependent protein kinase II delta (CaMKII delta) phosphorylates cardiac titin's spring elements. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 54:90-97(2013).
    Chen, QW; Edvinsson, L; et al. Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells. BMC CELL BIOLOGY 10:-(2009).

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