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CAMK2D

  • Official Full Name

    calcium/calmodulin-dependent protein kinase II delta

  • Overview

    The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
  • Synonyms

    CAMK2D; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin dependent protein kinase (CaM kinase) II delta , CAMKD; calcium/calmodulin-dependent protein kinase type II subunit delta; CaMK-II delta subunit; caMK-II subunit delta; CaM-k;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • MYC
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CAMK2D-266H Recombinant Human CAMK2D, GST-tagged, Active Sf9 Insect Cell GST
Human CAMK2D-0331H Active Recombinant Human CAMK2D Protein, GST-Tagged Insect Cell GST
Human CAMK2D-27263TH Recombinant Human CAMK2D N/A
Human CAMK2D-0332H Recombinant Human CAMK2D Protein, GST-Tagged Wheat Germ GST
Human CAMK2D-7878HCL Recombinant Human CAMK2D 293 Cell Lysate HEK293 N/A
Human CAMK2D-7879HCL Recombinant Human CAMK2D 293 Cell Lysate HEK293 N/A
Human CAMK2D-760H Recombinant Human CAMK2D Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CAMK2D-9327HF Active Recombinant Full Length Human CAMK2D Protein, GST-tagged Insect (sf21) GST 1-478
Human CAMK2D-0169H Recombinant Human CAMK2D Protein (A2-I499), Tag Free Insect Cell No tag A2-I499
Human CAMK2D-2739H Recombinant Human CAMK2D Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CAMK2D-0170H Recombinant Human CAMK2D Protein (A2-I499), GST tagged Insect Cell GST A2-I499
Human CAMK2D-2785HF Recombinant Full Length Human CAMK2D Protein, GST-tagged In Vitro Cell Free System GST 478 amino acids
Mouse CAMK2D-2281M Recombinant Mouse CAMK2D Protein, DDK-tagged Insect Cell DDK
Mouse Camk2d-030M Recombinant Mouse Camk2d Protein, DDK-tagged Insect Cell DDK
Mouse Camk2d-031M Recombinant Mouse Camk2d Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat CAMK2D-1102R Recombinant Rat CAMK2D Protein Mammalian Cell His
Rat CAMK2D-766R Recombinant Rat CAMK2D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CAMK2D-766R-B Recombinant Rat CAMK2D Protein Pre-coupled Magnetic Beads HEK293
Chicken CAMK2D-3360C Recombinant Chicken CAMK2D Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CAMK2D Related Articles

CAMK2D involved in several pathways and played different roles in them. We selected most pathways CAMK2D participated on our site, such as ErbB signaling pathway, Calcium signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAMK2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ErbB signaling pathwayCAMK2A;MAP2K2A;CDKN1BB;PAK7;GRB2B;AKT3A;CAMK2B1;MAPK8B;CDKN1BA
Calcium signaling pathwaySLC25A6;GRIN1B;DRD1B;ADCY2B;PDGFRB;GRIN2C;CACNA1B;PTAFR;PLCB4
cAMP signaling pathwayMAPK9;TNNI3;HTR1B;CNGA3;FFAR2;RAC2;GIPR;RAP1B;PLN
HIF- signaling pathwayANGPT1;PIK3CA;TLR4;TIMP1;MAPK3;INS2;IL6;EIF4E2;PIK3R2
Oocyte meiosisINS;SGOL1;SMC1A;YWHAE2;PPP3CCB;ITPR1;CDC23;CAMK2G;CDC16
Adrenergic signaling in cardiomyocytesBCL2;GNAIA;ATP1A2;GNAS;MAPK11;PPP2R5A;PIK3CA;ATP1A2A;ATF4B1
Wnt signaling pathwayWNT8A;RAC1B;PRKCG;GPC4;DAAM1B;FZD7B;MAPK8;CUL1;CCND1
Circadian entrainmentCACNA1H;GRIN2C;MTNR1B;KCNJ9;GRIA3;PER2;PRKG1;GNAI1;GRIN1
Long-term potentiationGRIN2A;PRKCA;PPP1R1A;CALML5;PPP3R1;RAP1B;HRAS;CAMK4;CAMK2D
Neurotrophin signaling pathwaySHC2;MAPK13;RPS6KA1;NGFRAP1;BAX;IRAK2;CALM1;BCL2;TP53
Cholinergic synapseCHRNB2;JAK2;CHRNA4;CREB3L2;PIK3CB;PRKACA;GNAO1;CHRM3;CREB3L1
Dopaminergic synapseGNB2;GNG13;PRKACG;PPP1CC;GNG3;PPP2R2A;CALM2;GRIA1;GSK3A
Olfactory transductionOLFR493;ARRB2;OLFR867;OR3A2;GNG13;OR2L2;RGS2;OR11A1;OLFR149
Inflammatory mediator regulation of TRP channelsPLCB4;ALOX12;PIK3R3;PPP1CA;CYP2C50;ALOX12E;PRKACG;CYP4A12A;TRPV2
Insulin secretionADCYAP1;STX1A;VAMP2;PRKCB;PRKACB;KCNN4;PRKCG;INS1;SNAP25
GnRH signaling pathwayGNA11B;ELK1;CACNA1SA;CALM2;NRAS;MAP2K2;CAMK2G1;CGNRH-R;MAPK8
MelanogenesisCALM3B;FZD3A;FZD9;WNT4A;WNT8B;WNT1;POMCA;Fzd4;CALM
Oxytocin signaling pathwayOXTR;PPP3CB;RYR1;CAMKK2;GNAS;PRKCA;EEF2K;CAMK1G;CACNB4
Aldosterone synthesis and secretionHSD3B6;CYP11A1;ITPR2;CAMK2B;CAMK2D;ITPR3;CYP21A1;AGTR1;CALM3
Gastric acid secretionMYLK4;CCKBR;KCNJ2;Car2;GNAI3;ATP1A1;SSTR2;KCNK2;KCNJ10
TuberculosisIL12B;LSP1;TRAF6;ITGAM;IFNA21;FCGR2A;IFNA2;NFKB1;CD209
Proteoglycans in cancerWNT2;MAPK3;RPS6KB1;FLNA;PRKACG;ITGB3;IL12B;MRAS;PRKCB
GliomaPDGFA;GRB2;Pdgfa&Pdgfb;PLCG1;PDGFRA;PRKCB;SHC3;MAP2K2;CALM3

CAMK2D has several biochemical functions, for example, ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CAMK2D itself. We selected most functions CAMK2D had, and list some proteins which have the same functions with CAMK2D. You can find most of the proteins on our site.

Function Related Protein
ATP bindingCDK17;SIK3;CLK1;FAM20B;UBE2R2;SRPK1;MYHC4;MAP3K2;PDGFRA
calmodulin bindingPPP3R1;CAMKK2;RGS2;SNTB1;TRPM4;PHKB;SLC14A2;PHKG1A;PPP3CA
calmodulin-dependent protein kinase activityCAMKK2;CAMK2D;MKNK1;CAMK1GB;DAPK1;CAMK1GA;CAMK1D;CAMK2D2;CAMKK1
ion channel bindingACTN3;CTNNB1;PKP2;SCN5A;FAM115A;KCNC1;KCNJ11;PACS1A;SLC8A1
nitric-oxide synthase bindingDNM2;CD74;CALM1;CALM2;CAV3;SCN5A;SNTA1;SLC14A2;ACTB
protein bindingFGFR1OP2;TIFA;KLF10;PPP1R1A;CUL1;MT1A;TNFRSF12A;FAM212A;EIF2S1
protein homodimerization activityNOG;ABCD1;CADM1;CEBPE;MID1;TERFA;HSD17B4;DCK;PTPRO
protein serine/threonine kinase activityCAMK1DB;TSSK2;CAMKK1B;ADCK4;PRKACAB;BMPR1AA;RPS6KA1;KSR2;TAOK3
sodium channel inhibitor activitySCN1B;PCSK9;NEDD4;SLC14A2;NEDD4L;CAMK2D
titin bindingANKRD2;CALM;CAPN3;ANKRD1;MYBPC3;CALM1;CALM3;ANKRD23;OBSCN

CAMK2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAMK2D here. Most of them are supplied by our site. Hope this information will be useful for your research of CAMK2D.

SCN5A; TNPO2; DNAL4

Hidalgo, CG; Chung, CS; et al. The multifunctional Ca2+/calmodulin-dependent protein kinase II delta (CaMKII delta) phosphorylates cardiac titin's spring elements. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 54:90-97(2013).
Chen, QW; Edvinsson, L; et al. Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells. BMC CELL BIOLOGY 10:-(2009).
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