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CREB3L2

  • Official Full Name

    cAMP responsive element binding protein 3-like 2

  • Overview

    CREB3L2 is a member of the old astrocyte specifically induced substance (OASIS) DNA binding and basic leucine zipper dimerization (bZIP) family of transcription factors, which includes CREB3 (MIM 606443) and CREB4 (MIM 607138).
  • Synonyms

    CREB3L2; cAMP responsive element binding protein 3-like 2; cyclic AMP-responsive element-binding protein 3-like protein 2; BBF2H7; TCAG_1951439; Basic transcription factor 2; BBF2 human homolog on chromosome 7; BZIB transcription factor; cAMP responsive element binding protein 3 like 2; cAMP-responsive element-binding protein 3-like protein 2; FUS/BBF2H7 protein; MGC131709; MGC71006; OTTHUMP00000208572; OTTHUMP00000208573; B-ZIB transcription factor; cAMP-responsive element-binding;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Danio rerio (Zebrafish) (Brachydanio rerio)
  • Human
  • Mouse
  • Rat
  • Xenopus laevis (African clawed frog)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CREB3L2-11561H Recombinant Human CREB3L2, GST-tagged E.coli GST 1-247a.a.
Human CREB3L2-1845H Recombinant Human CREB3L2 Protein, GST-tagged Wheat Germ GST
Human CREB3L2-7288HCL Recombinant Human CREB3L2 293 Cell Lysate HEK293 N/A
Human CREB3L2-2263HF Recombinant Full Length Human CREB3L2 Protein, GST-tagged In Vitro Cell Free System GST 247 amino acids
Mouse CREB3L2-3889M Recombinant Mouse CREB3L2 Protein Mammalian Cell His
Mouse CREB3L2-1965M-B Recombinant Mouse CREB3L2 Protein Pre-coupled Magnetic Beads HEK293
Mouse CREB3L2-1965M Recombinant Mouse CREB3L2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CREB3L2-1590R Recombinant Rat CREB3L2 Protein Mammalian Cell His
Rat CREB3L2-1247R Recombinant Rat CREB3L2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CREB3L2-1247R-B Recombinant Rat CREB3L2 Protein Pre-coupled Magnetic Beads HEK293
Danio rerio (Zebrafish) (Brachydanio rerio) RFL36301DF Recombinant Full Length Danio Rerio Cyclic Amp-Responsive Element-Binding Protein 3-Like Protein 2(Creb3L2) Protein, His-Tagged E.coli expression system His Full Length (1-519)
Xenopus laevis (African clawed frog) RFL30438XF Recombinant Full Length Xenopus Laevis Cyclic Amp-Responsive Element-Binding Protein 3-Like Protein 2(Creb3L2) Protein, His-Tagged E.coli expression system His Full Length (1-525)
Zebrafish CREB3L2-5131Z Recombinant Zebrafish CREB3L2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CREB3L2 involved in several pathways and played different roles in them. We selected most pathways CREB3L2 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CREB3L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
cGMP-PKG signaling pathwayGNAI1;GNA11;PLN;ATP1B1;CALM4;GNAI3;BAD;PPP3R1;PRKG1
cAMP signaling pathwayCAMK2D;GRIA3;SLC9A1;ROCK2;TSHR;PRKACG;ATP2B4;AKT1;ACOX1
PIK-Akt signaling pathwayITGA9;PDGFA;FOXO3;CCND1;ITGB4;THBS1;PPP2R1A;Itga10&Itgb1;HGF
AMPK signaling pathwaySIRT1;PIK3CD;PPP2R1A;PIK3R3;PPP2R3C;PCK1;GYS2;IGF1R;PFKL
Adrenergic signaling in cardiomyocytesACTC1A;ATP1A1B;TPM1;CACNG4;GNAIA;KCNE1;PPP2R2BB;PPP2CB;CACNA1DA
TNF signaling pathwayTRAF2;MAP3K14;VEGFC;VCAM1;NFKB1;AKT2;PIK3CB;RIPK1;SOCS3
Cholinergic synapsePIK3R5;CHRNA6;KCNJ3;GNG7;CREB3L3;KRAS;ITPR3;PLCB4;PRKCA
Dopaminergic synapsePRKCB;CREB5;PPP2R5C;MAPK9;GNG12;GSK3A;GNAQ;CREB3L4;PPP1CB
Insulin secretionCREB3L2;RYR2;GNAQ;PCLO;ATP1A3;GIP;ATP1B1;ADCYAP1;KCNN1
Estrogen signaling pathwayHSPA1A;CALM1;KCNJ5;GNAO1;MAP2K2;GNAI3;AKT1;FKBP4;CREB3L1
MelanogenesisPRKACAA;CAMK2D;PRKACG;PLCB2;FZD10;FZD2;TCF7;MAPK1;GNAO1B
Thyroid hormone synthesisGNAQ;TPO;PRKACB;CREB3L2;GSR;SLC5A5;ASGR2;FXYD2;CREB3L3
Aldosterone synthesis and secretionCAMK1G;CAMK2G;CALML3;PRKACB;CREB3L2;PRKCA;ITPR3;HSD3B1;CACNA1H
Insulin resistanceG6PC3;MLXIPL;INSB;PYGB;PYGM;CREB3L3L;RPS6KB2;SLC2A2;PTPRF
Huntingtons diseaseHAP1;TRP53;mt-Atp8;ATP5D;VDAC2;DNALC4;ATP5C1;GRIN1;COX6A1
Cocaine addictionGRIN2C;CREB3L2;CREB3L4;SLC18A2;SLC6A3;PRKACB;CREB3;DRD1A;DLG4
AlcoholismH2AFB2;HIST1H4H;HIST1H3E;GM14477;HIST1H3C;H3F3B;HRAS;GNG10;SOS1
Hepatitis BKRAS;MAPK9;TIRAP;TGFB2;NFKB1;FAS;SMAD4;PTK2B;CCNA1
Viral carcinogenesisHDAC8;IKBKG;TRAF5;PIK3CA;GTF2A1L;CDC20;SCIN;UBE3A;IRF7
Prostate cancerBAD;FOXO1;PDGFA;IKBKB;EP300;MAP2K2;HSP90B1;BRAF;Ar

CREB3L2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, cAMP response element binding, transcription regulatory region DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CREB3L2 itself. We selected most functions CREB3L2 had, and list some proteins which have the same functions with CREB3L2. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA bindingJUND;SOX10;POU2F2;SIX4;MYOD1;TFE3;DLX4;PGR;OTX2
cAMP response element bindingCREB3L3L;CREB3L4;ATF6B;CREB3L2;CREB3;E4F1;JUN;CREB3L3;CREB3L3A
transcription regulatory region DNA bindingTHRA;ZNF174;KLF2A;SMAD3;CDK9;SALL4;SNCA;BASP1;TRP63
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingKLF5;DLX5;NR3C1;TFE3A;TRP53;SRF;NCOA3;TCF4;NEUROD6

CREB3L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CREB3L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CREB3L2.

Dynll1; RGS16; GAS7; GCFC2; PXN; q5nfy4_fratt; RND1; PTP4A1; CEP19; GULP1; ZNF212

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