creb3l2
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  • Official Full Name
  • cAMP responsive element binding protein 3-like 2
  • Background
  • CREB3L2 is a member of the old astrocyte specifically induced substance (OASIS) DNA binding and basic leucine zipper dimerization (bZIP) family of transcription factors, which includes CREB3 (MIM 606443) and CREB4 (MIM 607138).
  • Synonyms
  • CREB3L2; cAMP responsive element binding protein 3-like 2; cyclic AMP-responsive element-binding protein 3-like protein 2; BBF2H7; TCAG_1951439; Basic transcription factor 2; BBF2 human homolog on chromosome 7; BZIB transcription factor; cAMP responsive element binding protein 3 like 2; cAMP-responsive element-binding protein 3-like protein 2; FUS/BBF2H7 protein; MGC131709; MGC71006; OTTHUMP00000208572; OTTHUMP00000208573; B-ZIB transcription factor; cAMP-responsive element-binding
Cat.#:CREB3L2-1845HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CREB3L2 Protein, GST-tagged
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Cat.#:CREB3L2-11561HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CREB3L2, GST-tagged
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Cat.#:CREB3L2-3889MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CREB3L2 Protein
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Cat.#:CREB3L2-1590RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CREB3L2 Protein
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Cat.#:CREB3L2-5131ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CREB3L2
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Cat.#:CREB3L2-7288HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CREB3L2 293 Cell Lysate
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Involved Pathway

CREB3L2 involved in several pathways and played different roles in them. We selected most pathways CREB3L2 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CREB3L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
cGMP-PKG signaling pathway
ATP2B4; CALM2; GNAI1; OPRD1; GTF2I; SLC25A4; PIK3R1; MYLK4; MEF2B; CALM1
cAMP signaling pathway
FFAR2; BRAF; GLI3; NPY1R; SUCNR1; GLP1R; GRIA1; RAC2; PDE4C; PIK3R2
PIK-Akt signaling pathway
EIF4E1B; HSP90B1; LAMA4; PDGFRB; IFNAR2; VTN; INSR; IFNAR1; NFKB1; TLR4
AMPK signaling pathway
PRKAA2; ELAVL1; STRADB; CCNA1; ADIPOQ; ADIPOR2; HMGCR; Scd1; TBC1D1; RPS6KB1
Adrenergic signaling in cardiomyocytes
Adcy4; TPM4A; CREM; CACNG1; ATP1A3A; AGTR1; PIK3R3; CREB3L3A; ADCY1; CACNA2D2
TNF signaling pathway
TRAF1; CXCL1; CXCL5; ATF4; MAP2K4; MAP2K3; MMP9; Casp3; PIK3R2; CASP8
Cholinergic synapse
AKR1C1; KCNQ1; SLC5A7; GNG7; MAPK1; CAMK2D; KCNJ4; GNG12; PIK3CA; GNG2
Dopaminergic synapse
CREB3L1; CALM2; DRD1; PPP2R2D; PRKCB; GNAI1; KIF5A; CALY; MAPK13; SLC6A3
Insulin secretion
GNA11; PDX1; CAMK2G; PCLO; KCNN3; ATF4; FXYD2; ATP1A3; PLCB4; SLC2A2
Estrogen signaling pathway
SHC1; PIK3R5; SOS1; CREB3L3; MAP2K1; PRKACB; NOS3; RAF1; CALML5; CALML3
Melanogenesis
Fzd4; GNAO1A; CALM2A; WNT6; CREB1A; WNT9A; GNAIA; ADCY1B; CAMK2G1; WNT8B
Thyroid hormone synthesis
PRKCA; TSHR; FXYD2; ATF4; LRP2; ATP1A3; ATP1A1; SLC26A4; GPX8; ATP1B2
Glucagon signaling pathway
PLCB4; PPP3CA; PRMT1; LDHA; PRKAG2; PHKG1; CAMK2B; CAMK2D; GNAS; CALML3
Aldosterone synthesis and secretion
HSD3B2; CYP11B2; PDE2A; NR4A1; CREB5; GNA11; PLCB4; ADCY9; CAMK2B; CALM4
Insulin resistance
PYGM; PTPN11A; PRKAA1; ACACB; PIK3CG; SLC2A4; G6PC3; GYS1; PIK3CD; PPP1R3B
Vasopressin-regulated water reabsorption
GNAS; CREB3L1; AVPR2; CREB5; DCTN5; PRKACB; DYNC2LI1; DYNC1LI1; AQP2; RAB5C
Huntingtons disease
CREB3L3; ATP5G1; NDUFB4; COX7C; CASP8; DNAI2; HTT; NDUFB5; TRP53; UQCRFS1
Cocaine addiction
MAOA; GRIA2; RELA; ATF6B; FOSB; GRIN2A; MAOB; RGS9; PRKACA; GNAI3
Amphetamine addiction
CREB3L3; CAMK2B; PPP3CA; CREB3L1; GRIA2; SLC18A2; CAMK2G; ATF4; DRD1; PPP3R2
Alcoholism
HIST1H2BQ; HDAC1; HIST1H3A; HIST1H2BA; GM14479; GNG5; HIST1H2AH; SOS1; MAPK1; GM14478
Hepatitis B
IFNA8; MAPK1; FAS; TLR2; MAVS; VDAC3; PIK3R5; IFNA6; CCNA2; CCNA1
Viral carcinogenesis
DNAJA3; YWHAE; DLG1; PRKACG; HIST1H2BB; CDC20; EP300; RBPJL; HDAC7; YWHAH
Prostate cancer
HSP90B1; MAPK1; SPINK1; ARAF; PDGFB; PIK3CA; SMARCD1; PDPK1; CREB3L1; BAD

Protein Function

CREB3L2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, cAMP response element binding, transcription regulatory region DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CREB3L2 itself. We selected most functions CREB3L2 had, and list some proteins which have the same functions with CREB3L2. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein MXD1; TBX3; POU4F3; ETV2; NEUROD6; MAFA; NRF1; NPAS4; PLAG1; JUNBB
Function cAMP response element binding
Related Protein CREB3L2; CREB1; CREB3L1; CREB3L3A; CREB3L3L; ATF6B; ATF6; JUN; CREB3L3; CREB3
Function transcription regulatory region DNA binding
Related Protein SOX6; GATA6; RFX3; TFAP2A; SMAD6; MTERF3; HIVEP2; ARID5A; HIVEP2A; ZFHX3
Function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein FOXL2; SOX9; ZIC3; NR2E1; SOX11; TRP53; EGR1; MITF; NR4A3; CREB3

Interacting Protein

CREB3L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CREB3L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CREB3L2.
Dynll1; RGS16; GAS7; GCFC2; PXN; q5nfy4_fratt; RND1; PTP4A1; CEP19; GULP1; ZNF212