|Official Full Name||E2F transcription factor 8|
|Background||This gene encodes a member of a family of transcription factors which regulate the expression of genes required for;progression through the cell cycle. The encoded protein regulates progression from G1 to S phase by ensuring the;nucleus divides at the proper time. Multiple alternatively spliced variants, encoding the same protein, have been;identified.|
|Synonyms||E2F8; E2F transcription factor 8; transcription factor E2F8; FLJ23311; E2F 8; E2F family member 82; E2F-8; E2F8_HUMAN; OTTHUMP00000231893; OTTHUMP00000231894; E2F family member 8|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
E2F8 involved in several pathways and played different roles in them. We selected most pathways E2F8 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with E2F8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
E2F8 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by E2F8 itself. We selected most functions E2F8 had, and list some proteins which have the same functions with E2F8. You can find most of the proteins on our site.
|RNA polymerase II core promoter proximal region sequence-specific DNA binding||NPAS4; TBP; MITFB; CEBPG; NKX2; NEUROG3; HOXD13; HOXC11; MZF1; ZNF460|
|core promoter binding||RB1; HDAC4; NEUROG3; HNRNPU; KLF4; FOXP3; SPI1; NKX3; MED1; CALCOCO1|
|protein binding||BCL2L1; MAGEA2; ZNF148; HIF1AN; KLRC4-KLRK1; NUDT14; HDGF2; THBS2; LRRFIP1; RIC8A|
|protein homodimerization activity||XDH; TNNC1; ACOT7; RCHY1; ATF3; LSM1; GPD1C; GYS2; BNIP3; TSG101|
|transcription corepressor activity||ZNF593; GMNN; NEUROD2; MAP3K10; SIRT6; DR1; EID1; TRIM22; KLF12; LIMD1|
|transcription factor activity, sequence-specific DNA binding||SOX9; HLFA; XBP1; NFIXB; SIX2; GTF2H2; ZFP628; MEF2A; RFX8; ZNF500|
|transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding||NACC2; MZF1; CC2D1A; NFIL3-5; GATA3; ZFPM1; SREBF2; NR2C1; TBX15; PROX1A|
E2F8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with E2F8 here. Most of them are supplied by our site. Hope this information will be useful for your research of E2F8.
TFCP2; FHL3; E2F7; ZDHHC17