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ERVFRD-1

  • Official Full Name

    endogenous retrovirus group FRD, member 1

  • Overview

    Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels,;suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus;provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope;glycoprotein gene which appears to have been selectively preserved. The genes protein product plays a major role in;placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope;protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a;heterodimer.
  • Synonyms

    ERVFRD-1; endogenous retrovirus group FRD, member 1; HERV-FRD_6p24.1 provirus ancestral Env polyprotein; envFRD; ERVFRDE1; HERV FRD; HERV W/FRD; syncytin 2; envelope polyprotein; endogenous retrovirus group FRD member 1; HERV-FRD provirus ancestral Env po;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ERVFRD-1-3492H Recombinant Human ERVFRD-1 Protein, GST-tagged Wheat Germ GST
Human ERVFRD-1-4694HF Recombinant Full Length Human ERVFRD-1 Protein, GST-tagged In Vitro Cell Free System GST 538 amino acids
  • ERVFRD-1 Related Articles

ERVFRD-1 involved in several pathways and played different roles in them. We selected most pathways ERVFRD-1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ERVFRD-1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ERVFRD-1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ERVFRD-1 itself. We selected most functions ERVFRD-1 had, and list some proteins which have the same functions with ERVFRD-1. You can find most of the proteins on our site.

Function Related Protein

ERVFRD-1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERVFRD-1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERVFRD-1.

Vargas, A; Zhou, SF; et al. Syncytin proteins incorporated in placenta exosomes are important for cell uptake and show variation in abundance in serum exosomes from patients with preeclampsia. FASEB JOURNAL 28:3703-3719(2014).
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