• Official Full Name
  • exocyst complex component 2
  • Background
  • The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts.
  • Synonyms
  • EXOC2; exocyst complex component 2; SEC5 like 1 (S. cerevisiae) , SEC5L1; FLJ11026; Sec5p; SEC5-like 1; exocyst complex component Sec5; SEC5; SEC5L1
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat EXOC2 Protein
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey EXOC2 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken EXOC2
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish EXOC2

EXOC2 Related Articles

Evers, C; Maas, B; et al. Mosaic Deletion of EXOC6B: Further Evidence for An Important Role of the Exocyst Complex in the Pathogenesis of Intellectual Disability. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:3088-3094(2014).
Liu, DM; Novick, P; et al. Bem1p contributes to secretory pathway polarization through a direct interaction with Exo70p. JOURNAL OF CELL BIOLOGY 207:59-72(2014).