• Official Full Name
  • F-box protein 9
  • Background
  • This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5 terminus.
  • Synonyms
  • FBXO9; F-box protein 9; F box only protein 9; F-box only protein 9; FBX9; NY REN 57; F-box protein Fbx9; cross-immune reaction antigen 1; renal carcinoma antigen NY-REN-57; VCIA1; NY-REN-57; dJ341E18.2; KIAA0936; DKFZp434C0118
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FBXO9 Protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FBXO9, GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FBXO9 Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FBXO9 Protein
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FBXO9 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FBXO9
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FBXO9
Source (Host):Species:Human
Product nameRecombinant Human FBXO9 293 Cell Lysate

Protein Function

FBXO9 has several biochemical functions, for example, protein binding, ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO9 itself. We selected most functions FBXO9 had, and list some proteins which have the same functions with FBXO9. You can find most of the proteins on our site.
Related Protein
Function protein binding
Related Protein LBP; F10; CORO1A; ITSN1; APOO; SPI1B; 2610109H07Rik; CACFD1; LOXL3; STAM
Function ubiquitin-protein transferase activity
Related Protein RNF141; TRAF2; PEX12; TRIM24; RNF146; KLHL20; PJA2; MIB2; TRIP12; RNF220

Interacting Protein

FBXO9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO9 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO9.
HSP90AB1; SKP1; hmsH; pckA

FBXO9 Related Articles

Lee, KW; Kwak, SH; et al. F-box only protein 9 is required for adipocyte differentiation. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 435:239-243(2013).
Fernandez-Saiz, V; Targosz, BS; et al. SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma. NATURE CELL BIOLOGY 15:72-U164(2013).