galnt11
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  • Official Full Name
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
  • Background
  • Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward Muc1, Muc4.1, and EA2 than GALNT1. Does not appear to be involved in glycosylation of erythropoietin.
  • Synonyms
  • GALNT11; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11); polypeptide N-acetylgalactosaminyltransferase 11; FLJ21634; GALNAC-T11; pp-GaNTase 11; polypeptide GalNAc transferase 11; protein-UDP acetylgalactos
Cat.#:GALNT11-001HTag:His
Source (Host):CHOSpecies:Human
Product nameRecombinant Human GALNT11 Protein, His-tagged
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Cat.#:GALNT11-6181MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GALNT11 Protein
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Cat.#:GALNT11-4470ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GALNT11
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Involved Pathway

GALNT11 involved in several pathways and played different roles in them. We selected most pathways GALNT11 participated on our site, such as Mucin type O-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GALNT11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Mucin type O-Glycan biosynthesis
GALNTL5; C1GALT1C1; ST6GALNAC1; GALNT2; GALNTL6; GALNT9; GALNT5; ST3GAL2; WBSCR17; GALNT18
Metabolic pathways
ACAA1A; POLA2; TYR; DEGS2; ITGB1BP3; CHIA; GPI1; MTHFS; LCT; TYRP1B

Protein Function

GALNT11 has several biochemical functions, for example, Notch binding, carbohydrate binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GALNT11 itself. We selected most functions GALNT11 had, and list some proteins which have the same functions with GALNT11. You can find most of the proteins on our site.
Function
Related Protein
Function Notch binding
Related Protein NCOR2; HIF1AN; EGFL7; SNW1; AAK1; JAG1B; DLL4; NOTCH4; NOTCH1; DLL3
Function carbohydrate binding
Related Protein CLEC4A2; CLEC2B; CLEC5A; KLRF1; GCKR; KLRG1; Fcer2a; SI; GALNT9; CLEC12A
Function metal ion binding
Related Protein CA14; DMRT2; ZNF221; PPP3CC; ZFP746; BAK1; A3GALT2; DMRTA1; PON3; MTL5
Function polypeptide N-acetylgalactosaminyltransferase activity
Related Protein GALNT1; GALNT7; GALNT11; GALNTL2; GALNT10; C1GALT1C1; GALNT5; GALNTL4; GALNT3; GALNT13
Function transferase activity
Related Protein CAMKK1A; RAF1B; OXCT1A; SGK2B; GRK1A; ROCK2B; B3GNT2A; KAT6A; FUT9D; UGT5A5
Function transferase activity, transferring glycosyl groups
Related Protein EXT1B; GALNT18A; B3GAT1A; UGT5G2; A3GALT2; EXT1A; B3GNT2A; PIGB; C1GALT1B; PYGMA

Interacting Protein

GALNT11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GALNT11 here. Most of them are supplied by our site. Hope this information will be useful for your research of GALNT11.
Ywhaz; Hsd3b4

GALNT11 Related Articles

Yuasa, I; Umetsu, K; et al. Investigation of Japanese-specific alleles: Most are of Jomon lineage. LEGAL MEDICINE 17:52-55(2015).
Libisch, MG; Casas, M; et al. GALNT11 as a new molecular marker in chronic lymphocytic leukemia. GENE 533:270-279(2014).