gtf2a1l
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  • Official Full Name
  • general transcription factor IIA, 1-like
  • Background
  • The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
  • Synonyms
  • GTF2A1L; general transcription factor IIA, 1-like; TFIIA-alpha and beta-like factor; ALF; TFIIA alpha/beta like factor; Stonin 1; General transcription factor II A 1 like factor; GTF2A1LF; SALF; TFIIA alpha and beta like factor; GTF2A1-like factor; OTTHUMP00000201062; OTTHUMP00000201165; TFIIA-alpha/beta-like factor; TFIIA large subunit isoform ALF; general transcription factor II A, 1-like factor; Limulus Antilipopolysaccharide Factor; LALF
Cat.#:GTF2A1L-418HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2A1L Protein, His-tagged
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Cat.#:GTF2A1L-458HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GTF2A1L Protein, GST-tagged
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Cat.#:GTF2A1L-7351MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GTF2A1L Protein
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Cat.#:GTF2A1L-4504CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GTF2A1L
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Cat.#:GTF2A1L-4478ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GTF2A1L
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Cat.#:ALF-240LTag:N/A
Source (Host):YeastSpecies:
Product nameRecombinant Limulus Antilipopolysaccharide Factor
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Cat.#:GTF2A1L-5705HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GTF2A1L 293 Cell Lysate
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Involved Pathway

GTF2A1L involved in several pathways and played different roles in them. We selected most pathways GTF2A1L participated on our site, such as Basal transcription factors, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2A1L were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Basal transcription factors
GTF2E1; TAF13; TAF12; TAF1L; GTF2H3-2; TAF9; TAF1; GTF2A1; GTF2H2C; TAF5L
Viral carcinogenesis
SRF; RBL2; TBPL1; CCND3; HIST1H2BE; UBE3A; CCNE1; HIST1H4B; MAD1L1; NFKB1

Protein Function

GTF2A1L has several biochemical functions, for example, DNA binding, protein binding, transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2A1L itself. We selected most functions GTF2A1L had, and list some proteins which have the same functions with GTF2A1L. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZFP2; ZFP775; KLF3; GATA1; ZNF621; ZKSCAN5; POLG; POGZ; FAM170A; LHX1B
Function protein binding
Related Protein MAP3K11; TRIM55; BUD13; BCAP31; RHOT2; SSX2IP; CCP110; SPTSSA; OPA1; CRB3
Function transcription coactivator activity
Related Protein APEX1; PIAS2; NACA; JUND; SIX3; CBFB; NR2F1; PIAS1; SOX17; YAP1