• Official Full Name
  • hook homolog 1
  • Background
  • This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.
  • Synonyms
  • HOOK1; hook homolog 1 (Drosophila); protein Hook homolog 1; HK1; hHK1; h-hook1; MGC10642
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HOOK1 Protein, GST-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HOOK1
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HOOK1
Source (Host):Species:Human
Product nameRecombinant Human HOOK1 293 Cell Lysate

Protein Function

HOOK1 has several biochemical functions, for example, actin binding, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOOK1 itself. We selected most functions HOOK1 had, and list some proteins which have the same functions with HOOK1. You can find most of the proteins on our site.
Related Protein
Function actin binding
Related Protein DIAP3; SLC4A1; MYPN; CFL2L; TPM1; TLN2A; ENC1; CAPZA1A; WASB; CCR5
Function identical protein binding
Related Protein ZNF703; VPS4B; SIRT1; DIAP1; PTPRG; SOX10; SHARPIN; TRAF2; DAPK1; TRP53
Function protein binding
Related Protein PEAK1; SLC19A2; SYT2; IQCE; IRF2; DAK; BDKRB2; LRCH1; HIST1H2AL; SOAT1

Interacting Protein

HOOK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOOK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOOK1.

HOOK1 Related Articles

Richardson, SCW; Winistorfer, SC; et al. Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton. MOLECULAR BIOLOGY OF THE CELL 15:1197-1210(2004).