• Official Full Name
  • homeobox B8
  • Background
  • This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
  • Synonyms
  • HOXB8; homeobox B8; homeo box B8 , HOX2, HOX2D; homeobox protein Hox-B8; Homeobox protein Hox B8; Homeobox protein HoxB8; HOX 2; Hox 2.4; HOX 2D; HOX B8; HOX2; Hox2.4; HOX2D; homeo box 2D; homeo box B8; OTTHUMP00000216943; homeobox protein Hox-2D; homeobox protein Hox-2.4; Hox-2.4
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HOXB8 Protein, His-tagged
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HOXB8 Protein, GST-tagged
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey HOXB8 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HOXB8
Source (Host):Species:Human
Product nameRecombinant Human HOXB8 293 Cell Lysate

Protein Function

HOXB8 has several biochemical functions, for example, sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXB8 itself. We selected most functions HOXB8 had, and list some proteins which have the same functions with HOXB8. You can find most of the proteins on our site.
Related Protein
Function sequence-specific DNA binding
Related Protein AHR; RERE; EMX3; GSC; IRX3B; MAFGA; GSX2; NR1D4A; ZNF500; ATF4B2
Function transcription factor activity, sequence-specific DNA binding
Related Protein NKX2-1; HOXC4; HNF1B; NFAT5; ZFP11; HMGA1A; PPARAA; CREB3L3L; ZNF274; TCF3A