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HOXB8

  • Official Full Name

    homeobox B8

  • Overview

    This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
  • Synonyms

    HOXB8; homeobox B8; homeo box B8 , HOX2, HOX2D; homeobox protein Hox-B8; Homeobox protein Hox B8; Homeobox protein HoxB8; HOX 2; Hox 2.4; HOX 2D; HOX B8; HOX2; Hox2.4; HOX2D; homeo box 2D; homeo box B8; OTTHUMP00000216943; homeobox protein Hox-2D; homeobox protein Hox-2.4; Hox-2.4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HOXB8-4968H Recombinant Human HOXB8 Protein, GST-tagged Wheat Germ GST
Human HOXB8-5420HCL Recombinant Human HOXB8 293 Cell Lysate HEK293 N/A
Human HOXB8-1894H Recombinant Human HOXB8 Protein, His-tagged E.coli His
Human HOXB8-3721HF Recombinant Full Length Human HOXB8 Protein, GST-tagged In Vitro Cell Free System GST 243 amino acids
Rhesus Macaque HOXB8-2132R Recombinant Rhesus monkey HOXB8 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HOXB8-1953R Recombinant Rhesus Macaque HOXB8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HOXB8-1953R-B Recombinant Rhesus Macaque HOXB8 Protein Pre-coupled Magnetic Beads HEK293
Chicken HOXB8-6473C Recombinant Chicken HOXB8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HOXB8 involved in several pathways and played different roles in them. We selected most pathways HOXB8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXB8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

HOXB8 has several biochemical functions, for example, sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXB8 itself. We selected most functions HOXB8 had, and list some proteins which have the same functions with HOXB8. You can find most of the proteins on our site.

Function Related Protein
sequence-specific DNA bindingZIC3;MSX2;SPIB;PBX1A;THRAA;PBX3B;SIX9;POU3F2B;DBX1A
transcription factor activity, sequence-specific DNA bindingPOU1F1;PBX1A;ELK1;FOXD1;RHOXF1;HOXC8;SOX13;SLAMF7;ZFP110

HOXB8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXB8 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXB8.

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