• Official Full Name
  • Hermansky-Pudlak syndrome 5
  • Background
  • This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.
  • Synonyms
  • HPS5; Hermansky-Pudlak syndrome 5; Hermansky-Pudlak syndrome 5 protein; ruby-eye protein 2 homolog; alpha integrin binding protein 63; alpha-integrin-binding protein 63; AIBP63; KIAA1017
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HPS5 Protein, GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HPS5 Protein
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HPS5
Source (Host):Species:Human
Product nameRecombinant Human HPS5 293 Cell Lysate

Interacting Protein

HPS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of HPS5.
BUB1; FGFR1OP; Lck; PHKG2; CSNK2A2; BLM; Magoh; Ppp2r1a; SMC6; Rassf1

HPS5 Related Articles

Jedlitschky, G; Tirschmann, K; et al. The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage. BLOOD 104:3603-3610(2004).
Ward, DM; Shiflett, SL; et al. Use of expression constructs to dissect the functional domains of the CHS/Beige protein: Identification of multiple phenotypes. TRAFFIC 4:403-415(2003).
Moriyama, K; Bonifacino, JS; et al. Pallidin is a component of a multi-protein complex involved in the biogenesis of lysosome-related organelles. TRAFFIC 3:666-677(2002).
Israels, SJ; Odaibo, FS; et al. Deficient thromboxane synthesis and response in platelets from premature infants. PEDIATRIC RESEARCH 41:218-223(1997).