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HPS5

  • Official Full Name

    Hermansky-Pudlak syndrome 5

  • Overview

    This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.
  • Synonyms

    HPS5; Hermansky-Pudlak syndrome 5; Hermansky-Pudlak syndrome 5 protein; ruby-eye protein 2 homolog; alpha integrin binding protein 63; alpha-integrin-binding protein 63; AIBP63; KIAA1017;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HPS5-5017H Recombinant Human HPS5 Protein, GST-tagged Wheat Germ GST
Human HPS5-5394HCL Recombinant Human HPS5 293 Cell Lysate HEK293 N/A
Human HPS5-3631HF Recombinant Full Length Human HPS5 Protein, GST-tagged In Vitro Cell Free System GST 1015 amino acids
Mouse HPS5-7836M Recombinant Mouse HPS5 Protein Mammalian Cell His
Mouse Hps5-3437M Recombinant Mouse Hps5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse HPS5-4310M Recombinant Mouse HPS5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HPS5-4310M-B Recombinant Mouse HPS5 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HPS5-5624Z Recombinant Zebrafish HPS5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HPS5 Related Articles

HPS5 involved in several pathways and played different roles in them. We selected most pathways HPS5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HPS5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

HPS5 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by HPS5 itself. We selected most functions HPS5 had, and list some proteins which have the same functions with HPS5. You can find most of the proteins on our site.

Function Related Protein

HPS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of HPS5.

BUB1; FGFR1OP; Lck; PHKG2; CSNK2A2; BLM; Magoh; Ppp2r1a; SMC6; Rassf1

Jedlitschky, G; Tirschmann, K; et al. The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage. BLOOD 104:3603-3610(2004).
Ward, DM; Shiflett, SL; et al. Use of expression constructs to dissect the functional domains of the CHS/Beige protein: Identification of multiple phenotypes. TRAFFIC 4:403-415(2003).
Moriyama, K; Bonifacino, JS; et al. Pallidin is a component of a multi-protein complex involved in the biogenesis of lysosome-related organelles. TRAFFIC 3:666-677(2002).
Israels, SJ; Odaibo, FS; et al. Deficient thromboxane synthesis and response in platelets from premature infants. PEDIATRIC RESEARCH 41:218-223(1997).
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