Limitin, also called, Interferon (IFN)-Zeta, is an interferon-like cytokine that suppresses B lymphopoiesis through ligation of the interferon-alpha/beta (IFN-alpha/beta) receptor. limitin not only modified the proliferation and function of peripheral T lymphocytes, natural killer cells, and bone marrow stromal cells but also had antiviral activity.
Ifnz has several biochemical functions, for example, cytokine activity, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ifnz itself. We selected most functions Ifnz had, and list some proteins which have the same functions with Ifnz. You can find most of the proteins on our site.
Function cytokine activity
Related Protein GPI; IL22; IL17C; IFNE; GDF3; IFNA8; CSF1B; MSTN; EDN1; GPI1
Function type I interferon receptor binding
Related Protein Ifna15; IFNB1; IFNA3; GM13287; Gm13290; IFNA2; IFNA6; IFNW1; IFNA1; IFNPHI2
Ifnz Related Articles
Wang, CY; Hu, WX; et al. Adoptive Antitumor Immunotherapy In Vitro and In Vivo Using Genetically Activated erbB2-specific T Cells. JOURNAL OF IMMUNOTHERAPY 37:351-359(2014).
Connelley, TK; Longhi, C; et al. NKp46(+)CD3(+) Cells: A Novel Nonconventional T Cell Subset in Cattle Exhibiting Both NK Cell and T Cell Features. JOURNAL OF IMMUNOLOGY 192:3868-3880(2014).