LCE1A belongs to the late cornified envelope (LCE) gene cluster within the epidermal differentiation complex (EDC) on;chromosome 1. The LCE cluster contains multiple conserved genes that encode stratum corneum proteins, and these genes;are expressed relatively late during fetal assembly of the skin cornified envelope (Jackson et al., 2005 (PubMed;15854049)). For further information on the LCE gene cluster, see GENE FAMILY below.
LCE1A; late cornified envelope 1A; late cornified envelope protein 1A; LEP1; Late envelope protein 1; LCE1A_HUMAN
LCE1A Related Articles
Clements, SE; Techanukul, T; et al. Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology. BRITISH JOURNAL OF DERMATOLOGY 167:134-144(2012).
Tong, L; Corrales, RM; et al. Expression and regulation of cornified envelope proteins in human corneal epithelium. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 47:1938-1946(2006).